Gene Information gene info

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GENE：ESD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ESD
FullNmae esterase D
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3465
EnsembleID ENSG00000139684
Uniprot P10768

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ESD pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ESD mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ESD immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ESD GO:0005515,GO:0005788,GO:0005829,GO:0008150,GO:0016788,GO:0018738,GO:0031410,GO:0042802,GO:0046294,GO:0047374,GO:0052689,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ESD hsa:2098 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ESD hsa:2098 path:hsa01200 Carbon metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ESD 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ESD 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC ESD 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ESD 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ESD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ESD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ESD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ESD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ESD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ESD 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 ESD 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D ESD 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D ESD 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005E1A16 ESD 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000140295 ESD 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075AAA0 ESD 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000050CCE0 ESD 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFBE3 ESD 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004214BB ESD 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA ESD 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000345DEB ESD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013D17D ESD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 ESD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 ESD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 ESD 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 ESD 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ESD DDA1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ESD GRB2 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ESD FN1 25348397 N/A physical interaction ComPPI
ESD HDAC1 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ESD FSD2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ESD ACO2 25348397 N/A physical interaction ComPPI
ESD ADH5 25348397 N/A physical interaction ComPPI
ESD ALDH1B1 25348397 N/A physical interaction ComPPI
ESD ALDH2 25348397 N/A physical interaction ComPPI
ESD ALDH4A1 25348397 N/A physical interaction ComPPI
ESD OAT 25348397 N/A physical interaction ComPPI
ESD PDCD6IP 25348397 N/A physical interaction ComPPI
ESD RAE1 25348397 N/A physical interaction ComPPI
ESD TKT 25348397 N/A physical interaction ComPPI
ESD TPI1 25348397 N/A physical interaction ComPPI
ESD GPI 25348397 N/A physical interaction ComPPI
ESD PITPNB 25348397 N/A physical interaction ComPPI
ESD UFM1 25348397 N/A physical interaction ComPPI
ESD NTRK1 25348397 N/A physical interaction ComPPI
ESD CRK 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ESD PLCG2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ESD KEAP1 25348397 N/A physical interaction ComPPI
ESD MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ESD TRAF6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ESD HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ESD VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
ESD OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
ESD KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
SMARCB1 ESD 24234451 30108113 association proximity-dependent biotin identification IntAct

Visualization










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