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GENE：HECTD3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HECTD3
FullNmae HECT domain E3 ubiquitin protein ligase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26117
EnsembleID ENSG00000126107
Uniprot Q5T447

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HECTD3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HECTD3 GO:0004842,GO:0004842,GO:0004842,GO:0005515,GO:0016567,GO:0019905,GO:0043161,GO:0043161,GO:0048471

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 HECTD3 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAVS HECTD3 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 HECTD3 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 HECTD3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 HECTD3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 HECTD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HECTD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HECTD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HECTD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003380CC HECTD3 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 HECTD3 19088304 22473208 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS00003D5391 HECTD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE HECTD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003E226A HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075D15B HECTD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004ACAAA HECTD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F HECTD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 HECTD3 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
STX8 HECTD3 25361965 interaction type N/A PTMCode2
HECTD3 STX8 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPL HECTD3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCDC130 HECTD3 25348397 N/A physical interaction ComPPI
HSP90AB1 HECTD3 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SMAD2 HECTD3 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
FOSL2 HECTD3 25348397 N/A physical interaction ComPPI
HSP90AA1 HECTD3 25348397 N/A physical interaction ComPPI
NTRK1 HECTD3 25348397 N/A physical interaction ComPPI
SERPINA5 HECTD3 25348397 N/A physical interaction ComPPI
BAG6 HECTD3 25348397 N/A physical interaction ComPPI
CASP8 HECTD3 25348397 N/A physical interaction ComPPI
PARD6B HECTD3 25348397 N/A physical interaction ComPPI
ZDHHC17 HECTD3 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
STX8 HECTD3 25348397 N/A physical interaction ComPPI
CCNG1 HECTD3 25348397 N/A physical interaction ComPPI
ANGPT2 HECTD3 25348397 N/A physical interaction ComPPI
CAVIN1 HECTD3 25348397 N/A physical interaction ComPPI
BRCA1 HECTD3 25348397 N/A physical interaction ComPPI
COPS7B HECTD3 25348397 N/A physical interaction ComPPI
MALT1 HECTD3 23358872 25348397 27898060 N/A physical interaction ComPPI,OmniPath
GAST HECTD3 25348397 N/A physical interaction ComPPI
MRPS34 HECTD3 25348397 N/A physical interaction ComPPI
CHRDL1 HECTD3 25348397 N/A physical interaction ComPPI
NKAP HECTD3 25348397 N/A physical interaction ComPPI
MAVS HECTD3 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS4X HECTD3 25348397 N/A physical interaction ComPPI
ZZEF1 HECTD3 25348397 N/A physical interaction ComPPI
TRIOBP HECTD3 25348397 N/A physical interaction ComPPI
EGFL6 HECTD3 25348397 N/A physical interaction ComPPI
NCAPH HECTD3 25348397 N/A physical interaction ComPPI
TP53 HECTD3 25348397 N/A physical interaction ComPPI
ODAD4 HECTD3 25348397 N/A physical interaction ComPPI
MRPS24 HECTD3 25348397 N/A physical interaction ComPPI
HSP90AA2P HECTD3 25348397 N/A physical interaction ComPPI
HECTD3 RSPO1 25348397 N/A physical interaction ComPPI
HECTD3 MRM1 25348397 N/A physical interaction ComPPI
HECTD3 POGLUT1 25348397 N/A physical interaction ComPPI
HECTD3 SCCPDH 25348397 N/A physical interaction ComPPI
HECTD3 TRMT10C 25348397 N/A physical interaction ComPPI
HECTD3 ZNF317 25348397 N/A physical interaction ComPPI
HECTD3 WNT9B 25348397 N/A physical interaction ComPPI
HECTD3 UBXN10 25348397 N/A physical interaction ComPPI
HECTD3 RBFA 25348397 N/A physical interaction ComPPI
HECTD3 LYZL1 25348397 N/A physical interaction ComPPI
HECTD3 LYZL2 25348397 N/A physical interaction ComPPI
HECTD3 ZBBX 25348397 N/A physical interaction ComPPI
HECTD3 CPA6 25348397 N/A physical interaction ComPPI
HECTD3 WFDC10A 25348397 N/A physical interaction ComPPI
HECTD3 CLEC3A 25348397 N/A physical interaction ComPPI
HECTD3 GAS2L1 25348397 N/A physical interaction ComPPI
SLC2A1 HECTD3 24234451 30021884 physical association cross-linking study IntAct
MAVS HECTD3 21903422 27898060 N/A N/A OmniPath

Visualization










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