GENE:IL15RA
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | IL15RA |
FullNmae | interleukin 15 receptor subunit alpha |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:5978 |
EnsembleID | ENSG00000134470 |
Uniprot | Q13261 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
IL15RA | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
IL15RA | GO:0000139,GO:0001779,GO:0004896,GO:0005515,GO:0005615,GO:0005768,GO:0005789,GO:0005886,GO:0007259,GO:0009986,GO:0010977,GO:0019901,GO:0030659,GO:0031667,GO:0031965,GO:0032825,GO:0035723,GO:0035723,GO:0042010,GO:0042010,GO:0050766 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
IL15RA | hsa:3601 | path:hsa04060 | Cytokine-cytokine receptor interaction - Homo sapiens (human) |
IL15RA | hsa:3601 | path:hsa04630 | JAK-STAT signaling pathway - Homo sapiens (human) |
IL15RA | hsa:3601 | path:hsa04672 | Intestinal immune network for IgA production - Homo sapiens (human) |
IL15RA | hsa:3601 | path:hsa05166 | Human T-cell leukemia virus 1 infection - Homo sapiens (human) |
IL15RA | hsa:3601 | path:hsa05200 | Pathways in cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
GATA1 | IL15RA | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | IL15RA | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | IL15RA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | IL15RA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | IL15RA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | IL15RA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | IL15RA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | IL15RA | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
SYK | IL15RA | 11714793 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
CASK | IL15RA | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
RCVRN | IL15RA | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
TRAF2 | IL15RA | 11064452 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,OmniPath |
CDK2 | IL15RA | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
AXL | IL15RA | 14525934 16308569 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
IL2RB | IL15RA | 14525934 23104097 24234451 25348397 7641685 | physical association | experimental interaction detection,molecular sieving,surface plasmon resonance,x-ray crystallography,in vitro,in vivo | ComPPI,HPRD,IntAct |
PIAS4 | IL15RA | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
IL2RG | IL15RA | 11418623 14525934 23104097 24234451 25348397 7641685 | physical association | experimental interaction detection,molecular sieving,x-ray crystallography,in vitro,in vivo | ComPPI,HPRD,IntAct |
IL15 | IL15RA | 14525934 16284400 23104097 24234451 25348397 7641685 | physical association | experimental interaction detection,molecular sieving,surface plasmon resonance,x-ray crystallography,in vitro,in vivo,surface plasmon resonance array | ComPPI,HPRD,IntAct |
IL15RA | CDK4 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
IL15RA | POLR2F | 25348397 | N/A | physical interaction | ComPPI |
BCL10 | IL15RA | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
IL15RA | STAT5A | 10582086 27898060 | stimulant | N/A | OmniPath |
IL15RA | STAT3 | 10582086 27898060 | stimulant | N/A | OmniPath |
IL15 | IL15RA | 15265897 16284400 17709786 27898060 7641685 8530383 | stimulant | N/A | OmniPath |
IL2RG | IL15RA | 11418623 15265897 27898060 7641685 | N/A | N/A | OmniPath |
IL2RB | IL15RA | 15265897 27898060 7641685 | N/A | N/A | OmniPath |
IL15RA | IL2RB | 17709786 27898060 7641685 | stimulant | N/A | OmniPath |
SYK | IL15RA | 11714793 27898060 | stimulant | N/A | OmniPath |