Gene Information gene info

GENE:IL15RA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IL15RA
FullNmae interleukin 15 receptor subunit alpha
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5978
EnsembleID ENSG00000134470
Uniprot Q13261

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IL15RA immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IL15RA GO:0000139,GO:0001779,GO:0004896,GO:0005515,GO:0005615,GO:0005768,GO:0005789,GO:0005886,GO:0007259,GO:0009986,GO:0010977,GO:0019901,GO:0030659,GO:0031667,GO:0031965,GO:0032825,GO:0035723,GO:0035723,GO:0042010,GO:0042010,GO:0050766

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IL15RA hsa:3601 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
IL15RA hsa:3601 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
IL15RA hsa:3601 path:hsa04672 Intestinal immune network for IgA production - Homo sapiens (human)
IL15RA hsa:3601 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
IL15RA hsa:3601 path:hsa05200 Pathways in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL2RB IL15RA 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 26192618 7512720 7521688 7523571 interaction type N/A ACSN
IL2RG IL15RA 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 26192618 7512720 7521688 7523571 interaction type N/A ACSN
IL15 IL15RA 10820393 12811837 14607946 16212621 16284400 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 23180781 23331499 24829413 25582338 26192618 7512720 7521688 7523571 8530383 stimulation,association,physical association surface plasmon resonance ACSN,InnateDB,SignaLink,SignaLink
JAK1 IL15RA 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 26192618 7512720 7521688 7523571 7543512 interaction type N/A ACSN
IL15RA STAT1 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 26192618 7512720 7521688 7523571 interaction type N/A ACSN
IFNAR1 IL15RA 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 26192618 7512720 7521688 7523571 7543512 interaction type N/A ACSN
IFNAR2 IL15RA 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 26192618 7512720 7521688 7523571 7543512 interaction type N/A ACSN
TYK2 IL15RA 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 26192618 7512720 7521688 7523571 7543512 interaction type N/A ACSN
IL15RA MICA 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 26192618 7512720 7521688 7523571 interaction type N/A ACSN
IL15RA MICB 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 26192618 7512720 7521688 7523571 interaction type N/A ACSN
IL15RA STAT3 10582086 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 23331499 24829413 25582338 26192618 7512720 7521688 7523571 interaction type,stimulation N/A ACSN,SignaLink
IL15RA STAT4 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 26192618 7512720 7521688 7523571 interaction type N/A ACSN
IL15RA STAT5A 10582086 23331499 stimulation N/A SignaLink,SignaLink

Source Target Pmid Interactiontype Methods Database
GATA1 IL15RA 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 IL15RA 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 IL15RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IL15RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 IL15RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS IL15RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 IL15RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 IL15RA N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
IL2RG IL15RA 25361965 interaction type N/A PTMCode2
IL15RA IL2RG 25361965 interaction type N/A PTMCode2
IL2RB IL15RA 25361965 interaction type N/A PTMCode2
IL15RA IL2RB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SYK IL15RA 11714793 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CASK IL15RA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RCVRN IL15RA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRAF2 IL15RA 11064452 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
CDK2 IL15RA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AXL IL15RA 14525934 16308569 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
IL2RB IL15RA 14525934 23104097 24234451 25348397 7641685 physical association experimental interaction detection,molecular sieving,surface plasmon resonance,x-ray crystallography,in vitro,in vivo ComPPI,HPRD,IntAct
PIAS4 IL15RA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL2RG IL15RA 11418623 14525934 23104097 24234451 25348397 7641685 physical association experimental interaction detection,molecular sieving,x-ray crystallography,in vitro,in vivo ComPPI,HPRD,IntAct
IL15 IL15RA 14525934 16284400 23104097 24234451 25348397 7641685 physical association experimental interaction detection,molecular sieving,surface plasmon resonance,x-ray crystallography,in vitro,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
IL15RA CDK4 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL15RA POLR2F 25348397 N/A physical interaction ComPPI
BCL10 IL15RA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
IL15RA STAT5A 10582086 27898060 stimulant N/A OmniPath
IL15RA STAT3 10582086 27898060 stimulant N/A OmniPath
IL15 IL15RA 15265897 16284400 17709786 27898060 7641685 8530383 stimulant N/A OmniPath
IL2RG IL15RA 11418623 15265897 27898060 7641685 N/A N/A OmniPath
IL2RB IL15RA 15265897 27898060 7641685 N/A N/A OmniPath
IL15RA IL2RB 17709786 27898060 7641685 stimulant N/A OmniPath
SYK IL15RA 11714793 27898060 stimulant N/A OmniPath

Visualization