Gene Information gene info

GENE:PDS5A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PDS5A
FullNmae PDS5 cohesin associated factor A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29088
EnsembleID ENSG00000121892
Uniprot Q29RF7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PDS5A mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PDS5A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PDS5A GO:0000775,GO:0000785,GO:0000785,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005694,GO:0005829,GO:0005886,GO:0006281,GO:0007064,GO:0007064,GO:0008156,GO:0051301

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PDS5A hsa:23244 path:hsa04110 Cell cycle - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TIRAP PDS5A 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAVS PDS5A 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
PDS5A POLR2F 23180781 23994473 physical association anti tag coimmunoprecipitation InnateDB
EZH2 PDS5A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
EED PDS5A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
PDS5A UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
AR PDS5A 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PDS5A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PDS5A 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PDS5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PDS5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PDS5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PDS5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PDS5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PDS5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PDS5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PDS5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PDS5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB PDS5A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 PDS5A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 PDS5A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 PDS5A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000237AF9 PDS5A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 PDS5A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 PDS5A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA PDS5A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD231 PDS5A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 PDS5A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000482389 PDS5A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 PDS5A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000004203C PDS5A 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DDX21 PDS5A 25348397 N/A physical interaction ComPPI
NSMCE2 PDS5A 25348397 N/A physical interaction ComPPI
FOXB1 PDS5A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RAD21 PDS5A 15855230 17112726 17113138 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BCL2L1 PDS5A 25348397 N/A physical interaction ComPPI
FOXG1 PDS5A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
EZH2 PDS5A 25348397 N/A physical interaction ComPPI
NOTCH1 PDS5A 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NFATC1 PDS5A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
JUN PDS5A 24234451 25348397 25609649 association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
UBC PDS5A 25348397 N/A physical interaction ComPPI
NTRK1 PDS5A 25348397 N/A physical interaction ComPPI
RPA1 PDS5A 25348397 N/A physical interaction ComPPI
TIRAP PDS5A 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYC PDS5A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
STAG1 PDS5A 15855230 17113138 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RPA2 PDS5A 25348397 N/A physical interaction ComPPI
RPA3 PDS5A 25348397 N/A physical interaction ComPPI
BRF2 PDS5A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MDM2 PDS5A 25348397 N/A physical interaction ComPPI
SMC1A PDS5A 17112726 17113138 23242214 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EGFR PDS5A 25348397 N/A physical interaction ComPPI
CD70 PDS5A 25348397 N/A physical interaction ComPPI
CCNB2 PDS5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMC3 PDS5A 15855230 17113138 17349791 19268589 19906707 21111234 22912589 24234451 25348397 26344197 27898060 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
EED PDS5A 25348397 N/A physical interaction ComPPI
H3C1 PDS5A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
APLNR PDS5A 25348397 N/A physical interaction ComPPI
VIPR2 PDS5A 25348397 N/A physical interaction ComPPI
RP2 PDS5A 25348397 N/A physical interaction ComPPI
FOXE1 PDS5A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TRIM25 PDS5A 25348397 N/A physical interaction ComPPI
FOXH1 PDS5A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
GYPB PDS5A 25348397 N/A physical interaction ComPPI
BRCA1 PDS5A 25348397 N/A physical interaction ComPPI
TEAD2 PDS5A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 PDS5A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
STAG2 PDS5A 15855230 17113138 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RFC1 PDS5A 25348397 N/A physical interaction ComPPI
CSNK2B PDS5A 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AKTIP PDS5A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SRRM1 PDS5A 25348397 N/A physical interaction ComPPI
RRP1B PDS5A 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
WAPL PDS5A 17112726 17113138 20360068 21111234 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
LYPD3 PDS5A 25348397 N/A physical interaction ComPPI
SIRT6 PDS5A 25348397 N/A physical interaction ComPPI
MAVS PDS5A 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDCA5 PDS5A 21111234 24234451 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SIRT7 PDS5A 25348397 N/A physical interaction ComPPI
PTP4A3 PDS5A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MAS1 PDS5A 25348397 N/A physical interaction ComPPI
BSG PDS5A 25348397 N/A physical interaction ComPPI
GSTK1 PDS5A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PDS5A WFDC5 25348397 N/A physical interaction ComPPI
PDS5A PDS5B 25348397 N/A physical interaction ComPPI
PDS5A NT5E 25348397 N/A physical interaction ComPPI
PDS5A DLK1 25348397 N/A physical interaction ComPPI
PDS5A SLC30A4 25348397 N/A physical interaction ComPPI
PDS5A SCN2B 25348397 N/A physical interaction ComPPI
PDS5A FOXI1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PDS5A FOXI2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PDS5A FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PDS5A FOXQ1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PDS5A SIGLECL1 25348397 N/A physical interaction ComPPI
PDS5A LAMP3 25348397 N/A physical interaction ComPPI
PDS5A SLC15A1 25348397 N/A physical interaction ComPPI
PDS5A CD83 25348397 N/A physical interaction ComPPI
PDS5A LPAR4 25348397 N/A physical interaction ComPPI
PDS5A SGO1 23242214 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDS5A PDS5A 15855230 24234451 physical association anti bait coimmunoprecipitation IntAct
PDS5A LACTB 24234451 30021884 physical association cross-linking study IntAct
H1-2 PDS5A 24234451 30021884 physical association cross-linking study IntAct
H1-5 PDS5A 24234451 30021884 physical association cross-linking study IntAct
MAVS PDS5A 21903422 27898060 N/A N/A OmniPath
TIRAP PDS5A 21903422 27898060 N/A N/A OmniPath

Visualization