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GENE：POLM

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol POLM
FullNmae DNA polymerase mu
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9185
EnsembleID ENSG00000122678
Uniprot Q9NP87

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
POLM immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
POLM autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
POLM GO:0003677,GO:0003887,GO:0003887,GO:0005515,GO:0005634,GO:0005654,GO:0006303,GO:0006303,GO:0006310,GO:0046872,GO:0071897

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
POLM hsa:27434 path:hsa03450 Non-homologous end-joining - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
POLM EME1 15703371 16697054 16738138 17483519 17631059 19346677 19473888 19772495 19808869 19847258 26192618 interaction type N/A ACSN
POLM MUS81 15703371 16697054 16738138 17483519 17631059 19346677 19473888 19772495 19808869 19847258 26192618 interaction type N/A ACSN
POLM MSH2 15703371 16697054 16738138 17483519 17631059 19346677 19473888 19772495 19808869 19847258 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
ETS1 POLM 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 POLM 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 POLM 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 POLM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF POLM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 POLM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 POLM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 POLM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS POLM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A POLM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF POLM 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 POLM 18185580 25416803 27292025 mrna cleavage,inhibition array technology,clip TarBase
URS00000CC005 POLM 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F305A POLM 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000010BD8D POLM 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000005481D POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 POLM 23313552 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002B3783 POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 POLM 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 POLM 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 POLM 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 POLM 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 POLM 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000058878F POLM 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002D2333 POLM 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000045DBD POLM 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 POLM 22135298 phosphorylation N/A PhosphoSite
POLM PCNA 25361965 interaction type N/A PTMCode2
PCNA POLM 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PCNA POLM 11724965 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
UBE2D1 POLM 25348397 N/A physical interaction ComPPI
PNMA1 POLM 25348397 N/A physical interaction ComPPI
UBE2D2 POLM 25348397 N/A physical interaction ComPPI
POLM UBE2D3 25348397 N/A physical interaction ComPPI
POLM UBE2H 25348397 N/A physical interaction ComPPI
POLM UBE2E1 25348397 N/A physical interaction ComPPI
POLM UBE2C 25348397 N/A physical interaction ComPPI
POLM IKZF3 25348397 N/A physical interaction ComPPI
POLM CEP55 25348397 N/A physical interaction ComPPI
POLM CTU2 25348397 N/A physical interaction ComPPI
POLM ACAD8 25348397 N/A physical interaction ComPPI
CDK2 POLM 23933132 27898060 N/A N/A OmniPath

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