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GENE：RAB10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RAB10
FullNmae RAB10, member RAS oncogene family
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9759
EnsembleID ENSG00000084733
Uniprot P61026

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RAB10 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RAB10 GO:0000139,GO:0003925,GO:0005515,GO:0005525,GO:0005768,GO:0005789,GO:0005794,GO:0005794,GO:0005802,GO:0005829,GO:0005856,GO:0005886,GO:0005886,GO:0005912,GO:0005925,GO:0005929,GO:0006893,GO:0007409,GO:0016192,GO:0016197,GO:0019003,GO:0019882,GO:0030659,GO:0030667,GO:0030670,GO:0030859,GO:0031489,GO:0031489,GO:0032593,GO:0032593,GO:0032869,GO:0032869,GO:0043001,GO:0045055,GO:0045200,GO:0048471,GO:0055037,GO:0055037,GO:0055038,GO:0070062,GO:0070382,GO:0071782,GO:0071786,GO:0072659,GO:0090150,GO:0097051,GO:0098609,GO:0098641,GO:1903361

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RAB10 hsa:10890 path:hsa04144 Endocytosis - Homo sapiens (human)
RAB10 hsa:10890 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ELAVL1 RAB10 15257295 23180781 physical association anti tag coimmunoprecipitation InnateDB
HNRNPD RAB10 15257295 23180781 physical association anti tag coimmunoprecipitation InnateDB
RNF2 RAB10 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR RAB10 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RAB10 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 RAB10 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 RAB10 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 RAB10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RAB10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RAB10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RAB10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RAB10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RAB10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RAB10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RAB10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 RAB10 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 RAB10 20584986 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS00003BBF48 RAB10 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000070B1D RAB10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 RAB10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 RAB10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000821E0 RAB10 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000017DBB8 RAB10 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 RAB10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F RAB10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 RAB10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA RAB10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 RAB10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000042E1F RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000DDD35 RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000039E1E1 RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000600E6 RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002B3783 RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000037D7E5 RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003883FE RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000298BA3 RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002D2333 RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000028D811 RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000572E11 RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000005A8ED RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000008F0CF RAB10 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075C1E1 RAB10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 RAB10 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003E226A RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000027080C RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000029D9F1 RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000044FD7 RAB10 20371350 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005E6F45 RAB10 20371350 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002FF522 RAB10 20371350 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000FC8EB RAB10 20371350 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002ED720 RAB10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C RAB10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEF5F RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005C1F22 RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018D2BE RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD RAB10 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000393C7 RAB10 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000105D19 RAB10 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MLPH RAB10 25361965 interaction type N/A PTMCode2
RAB10 MLPH 25361965 interaction type N/A PTMCode2
RAB10 RPH3AL 25361965 interaction type N/A PTMCode2
RPH3AL RAB10 25361965 interaction type N/A PTMCode2
RAB10 GDI1 25361965 interaction type N/A PTMCode2
GDI1 RAB10 25361965 interaction type N/A PTMCode2
RAB10 RPH3A 25361965 interaction type N/A PTMCode2
RPH3A RAB10 25361965 interaction type N/A PTMCode2
OPTN RAB10 25361965 interaction type N/A PTMCode2
RAB10 OPTN 25361965 interaction type N/A PTMCode2
MAP4K2 RAB10 25361965 interaction type N/A PTMCode2
RAB10 MAP4K2 25361965 interaction type N/A PTMCode2
SYTL4 RAB10 25361965 interaction type N/A PTMCode2
RAB10 SYTL4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RAB39A RAB10 24234451 25348397 26824392 30021884 association,physical association anti tag coimmunoprecipitation,cross-linking study ComPPI,IntAct
CDC73 RAB10 25348397 N/A physical interaction ComPPI
RABIF RAB10 24234451 25348397 26824392 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CFL1 RAB10 25348397 N/A physical interaction ComPPI
UBL4A RAB10 25348397 N/A physical interaction ComPPI
TRAF6 RAB10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VCP RAB10 25348397 N/A physical interaction ComPPI
OPTN RAB10 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RAB10 RIMS1 12578829 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RAB10 MTNR1A 14525934 17215244 24234451 25348397 26514267 association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
RAB10 RAB8A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB10 AP1S1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB10 DOK2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB10 AURKA 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB10 SYTL3 25348397 N/A physical interaction ComPPI
RAB10 MLPH 25348397 N/A physical interaction ComPPI
RAB10 ENOPH1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RAB10 MICAL1 25348397 N/A physical interaction ComPPI
RAB10 PPBP 25348397 N/A physical interaction ComPPI
RAB10 ELAVL1 25348397 N/A physical interaction ComPPI
RAB10 EVI5L 25348397 N/A physical interaction ComPPI
RAB10 APP 25348397 N/A physical interaction ComPPI
RAB10 ZMPSTE24 25348397 N/A physical interaction ComPPI
RAB10 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
RAB10 ITGA4 25348397 N/A physical interaction ComPPI
RAB10 ATP4A 25348397 N/A physical interaction ComPPI
RAB10 RPA3 25348397 N/A physical interaction ComPPI
RAB10 RPA2 25348397 N/A physical interaction ComPPI
RAB10 ASB17 25348397 N/A physical interaction ComPPI
RAB10 STAU1 25348397 N/A physical interaction ComPPI
RAB10 CUL7 25348397 N/A physical interaction ComPPI
RAB10 RNF2 25348397 N/A physical interaction ComPPI
RAB10 GDI2 24234451 25348397 26824392 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB10 GPI 25348397 N/A physical interaction ComPPI
RAB10 LGALS1 25348397 N/A physical interaction ComPPI
RAB10 PPIA 25348397 N/A physical interaction ComPPI
RAB10 FKBP2 25348397 N/A physical interaction ComPPI
RAB10 FUBP3 25348397 N/A physical interaction ComPPI
RAB10 HNRNPA3 25348397 N/A physical interaction ComPPI
RAB10 MAP3K15 25348397 N/A physical interaction ComPPI
RAB10 MDH2 25348397 N/A physical interaction ComPPI
RAB10 TAGLN2 25348397 N/A physical interaction ComPPI
RAB10 TKT 25348397 N/A physical interaction ComPPI
RAB10 UBE2L3 25348397 N/A physical interaction ComPPI
RAB10 RAB5C 25348397 N/A physical interaction ComPPI
RAB10 RAB7A 25348397 N/A physical interaction ComPPI
RAB10 TIAL1 25348397 N/A physical interaction ComPPI
RAB10 UQCRC2 25348397 N/A physical interaction ComPPI
RAB10 MED20 25348397 N/A physical interaction ComPPI
RAB10 TCTN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RAB10 CDH1 25348397 N/A physical interaction ComPPI
RAB10 MTMR14 25348397 N/A physical interaction ComPPI
RAB10 DUSP22 25348397 N/A physical interaction ComPPI
RAB10 TTC30B 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
RAB10 SDHA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RAB10 FOXA1 25348397 N/A physical interaction ComPPI
RAB10 TRIM25 25348397 N/A physical interaction ComPPI
RAB10 HNRNPL 25348397 N/A physical interaction ComPPI
RAB10 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RAB10 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RAB10 VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
RAB10 MICALL1 21951725 24234451 25348397 physical association two hybrid ComPPI,IntAct
RAB10 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RAB10 LRRK2 24234451 25348397 26824392 phosphorylation reaction,association,physical association anti tag coimmunoprecipitation,protein kinase assay ComPPI,IntAct
RAB10 RILPL1 24234451 25348397 26824392 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB10 CHM 24234451 25348397 26824392 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB10 CHML 24234451 25348397 26824392 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB10 RAB35 24234451 25348397 26824392 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB10 RAB19 24234451 25348397 26824392 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB10 MICAL3 24234451 25348397 26824392 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB10 RAB6C 24234451 25348397 26824392 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB10 RAB12 24234451 25348397 26824392 association anti tag coimmunoprecipitation ComPPI,IntAct
RAB10 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RPA1 RAB10 25348397 N/A physical interaction ComPPI
PKM RAB10 25348397 N/A physical interaction ComPPI
GDI1 RAB10 24234451 25348397 26496610 26824392 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SEPTIN9 RAB10 25348397 N/A two hybrid ComPPI
RAB33B RAB10 24234451 30021884 physical association cross-linking study IntAct
RPUSD4 RAB10 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS00009AE675 RAB10 27087310 direct interaction,inhibition N/A NPInter

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