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GENE：TGFB1I1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TGFB1I1
FullNmae transforming growth factor beta 1 induced transcript 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11767
EnsembleID ENSG00000140682
Uniprot O43294

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TGFB1I1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TGFB1I1 GO:0003713,GO:0003713,GO:0005515,GO:0005829,GO:0005856,GO:0005925,GO:0005925,GO:0007155,GO:0008285,GO:0010718,GO:0016055,GO:0016331,GO:0016363,GO:0030511,GO:0030855,GO:0043231,GO:0045165,GO:0045444,GO:0045599,GO:0045893,GO:0046872,GO:0048495,GO:0050681,GO:0062023,GO:0070411,GO:2000060

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TGFB1I1 SMAD1 21996749 interaction type,inhibition N/A SignaLink
TGFB1I1 SMAD5 21996749 interaction type,inhibition N/A SignaLink
TGFB1I1 SMAD7 21996749 interaction type,inhibition N/A SignaLink

Source Target Pmid Interactiontype Methods Database
TGFB1I1 NR3C1 20005715 interaction type N/A PSP
TGFB1I1 AR 20005715 interaction type N/A PSP
TGFB1I1 CSK 20005715 interaction type N/A PSP
TGFB1I1 PTK2 20005715 interaction type N/A PSP
TGFB1I1 PTK2B 11856738 11937718 18988627 20005715 21071413 9422762 interaction type N/A PSP,SignaLink
TGFB1I1 HIPK3 20005715 interaction type N/A PSP
TGFB1I1 AR 11155740 11779876 11779876 11856738 11856738 11856738 18988627 20005715 20005715 21071413 N/A N/A SignaLink
TGFB1I1 CSK 20005715 20005715 21071413 9858471 N/A N/A SignaLink
TGFB1I1 NR3C1 10848625 18988627 20005715 20005715 N/A N/A SignaLink
TGFB1I1 PTK2 20005715 20005715 21071413 21900206 9422762 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
GATA2 TGFB1I1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF TGFB1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TGFB1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TGFB1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TGFB1I1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 TGFB1I1 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
PTK2B TGFB1I1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
FYN TGFB1I1 22135298 phosphorylation N/A PhosphoSite
TGFB1I1 PTK2B 25361965 interaction type N/A PTMCode2
HSPB1 TGFB1I1 25361965 interaction type N/A PTMCode2
TGFB1I1 HSPB1 25361965 interaction type N/A PTMCode2
CSK TGFB1I1 25361965 interaction type N/A PTMCode2
TGFB1I1 CSK 25361965 interaction type N/A PTMCode2
MAPK15 TGFB1I1 25361965 interaction type N/A PTMCode2
TGFB1I1 MAPK15 25361965 interaction type N/A PTMCode2
NR3C1 TGFB1I1 25361965 interaction type N/A PTMCode2
TGFB1I1 NR3C1 25361965 interaction type N/A PTMCode2
AR TGFB1I1 25361965 interaction type N/A PTMCode2
TGFB1I1 AR 25361965 interaction type N/A PTMCode2
PTPN12 TGFB1I1 25361965 interaction type N/A PTMCode2
TGFB1I1 PTPN12 25361965 interaction type N/A PTMCode2
CRKL TGFB1I1 25361965 interaction type N/A PTMCode2
TGFB1I1 CRKL 25361965 interaction type N/A PTMCode2
TRAF4 TGFB1I1 25361965 interaction type N/A PTMCode2
TGFB1I1 TRAF4 25361965 interaction type N/A PTMCode2
TGFBR2 TGFB1I1 25361965 interaction type N/A PTMCode2
TGFB1I1 TGFBR2 25361965 interaction type N/A PTMCode2
VCL TGFB1I1 25361965 interaction type N/A PTMCode2
TGFB1I1 VCL 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FKBP1A TGFB1I1 12417722 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SMAD4 TGFB1I1 25348397 N/A physical interaction ComPPI
PTK2B TGFB1I1 11856738 11937718 14525934 25348397 9422762 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TGFBR2 TGFB1I1 12421567 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CBLB TGFB1I1 25348397 N/A physical interaction ComPPI
GP6 TGFB1I1 25348397 N/A physical interaction ComPPI
SMAD7 TGFB1I1 18762808 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CRKL TGFB1I1 11463817 14525934 25348397 9858471 N/A experimental interaction detection,in vitro ComPPI,HPRD
CBLC TGFB1I1 23145173 24831009 25348397 27898060 N/A physical interaction ComPPI,OmniPath
AR TGFB1I1 11155740 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,biochemical,in vivo ComPPI,HPRD
EP300 TGFB1I1 14525934 14755691 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SMAD3 TGFB1I1 14755691 15561701 25348397 27898060 N/A physical interaction ComPPI,OmniPath
GIT1 TGFB1I1 12153727 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PPP1CA TGFB1I1 24234451 25348397 25593058 association anti bait coimmunoprecipitation ComPPI,IntAct
PXN TGFB1I1 25348397 N/A physical interaction ComPPI
VCL TGFB1I1 25348397 N/A physical interaction ComPPI
NCF1 TGFB1I1 25348397 N/A physical interaction ComPPI
PTPN12 TGFB1I1 10092676 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SDC4 TGFB1I1 11805099 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
XPO1 TGFB1I1 25348397 N/A physical interaction ComPPI
CCNA1 TGFB1I1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CSK TGFB1I1 25348397 N/A physical interaction ComPPI
NEDD4L TGFB1I1 25348397 N/A physical interaction ComPPI
VHL TGFB1I1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TGFB1I1 SVIL 11792840 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGFB1I1 HSPB1 11546764 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
TGFB1I1 ITGA4 10604475 14525934 24234451 25348397 physical association affinity chromatography technology,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
TGFB1I1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TGFB1I1 GIT2 10330411 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGFB1I1 MAPK15 14525934 16624805 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGFB1I1 SLC6A3 12177201 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
TGFB1I1 NR3C1 10848625 14525934 25348397 27898060 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
TGFB1I1 TRAF4 12023963 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
TGFB1I1 HIPK3 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TGFB1I1 PTK2 21900206 24234451 25348397 9756887 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
TGFB1I1 GP1BB 25348397 N/A physical interaction ComPPI
TGFB1I1 NCF1B 25348397 N/A physical interaction ComPPI
TGFB1I1 CDKN2B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1I1 PLA2G3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFB1I1 HSPB2 25348397 N/A physical interaction ComPPI
TGFB1I1 TES 25348397 N/A physical interaction ComPPI
TGFB1I1 PLEKHH2 22832517 24234451 25348397 27898060 colocalization electron microscopy ComPPI,IntAct,OmniPath
TGFB1I1 SH2D1B 23322602 24234451 25348397 association pull down ComPPI,IntAct
FYN TGFB1I1 10838081 11856738 27898060 stimulant N/A OmniPath
PTK2B TGFB1I1 10838081 11856738 11937718 27898060 9422762 9858471 stimulant N/A OmniPath

Visualization










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