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GENE：TUSC3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TUSC3
FullNmae tumor suppressor candidate 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30242
EnsembleID ENSG00000104723
Uniprot Q13454

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TUSC3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TUSC3 GO:0005739,GO:0005789,GO:0005886,GO:0005886,GO:0006487,GO:0008250,GO:0008250,GO:0015095,GO:0015095,GO:0015693,GO:0018279,GO:0018279,GO:0050890,GO:0055085,GO:1903830

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TUSC3 hsa:7991 path:hsa00510 N-Glycan biosynthesis - Homo sapiens (human)
TUSC3 hsa:7991 path:hsa00513 Various types of N-glycan biosynthesis - Homo sapiens (human)
TUSC3 hsa:7991 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 TUSC3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 TUSC3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TUSC3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 TUSC3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 TUSC3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TUSC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TUSC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TUSC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TUSC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TUSC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TUSC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TUSC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 TUSC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 TUSC3 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000C85B2 TUSC3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001DE669 TUSC3 25416803 28288641 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
TUSC3 DAD1 25361965 interaction type N/A PTMCode2
DAD1 TUSC3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BMI1 TUSC3 25348397 N/A physical interaction ComPPI
GGT7 TUSC3 25348397 N/A physical interaction ComPPI
SLC9A3R2 TUSC3 25348397 N/A physical interaction ComPPI
PEX19 TUSC3 25348397 N/A physical interaction ComPPI
PPP1CA TUSC3 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
HNRNPL TUSC3 25348397 N/A physical interaction ComPPI
STXBP1 TUSC3 25348397 N/A physical interaction ComPPI
STXBP2 TUSC3 25348397 N/A physical interaction ComPPI
CHRND TUSC3 25348397 N/A physical interaction ComPPI
GABRD TUSC3 25348397 N/A physical interaction ComPPI
HTR3A TUSC3 25348397 N/A physical interaction ComPPI
UPK1A TUSC3 25348397 N/A physical interaction ComPPI
SCN3B TUSC3 25348397 N/A physical interaction ComPPI
GABRA3 TUSC3 25348397 N/A physical interaction ComPPI
RPN2 TUSC3 25348397 N/A physical interaction ComPPI
FBXO6 TUSC3 25348397 N/A physical interaction ComPPI
TUSC3 MCOLN3 25348397 N/A physical interaction ComPPI
TUSC3 SYNE4 25348397 N/A physical interaction ComPPI
TUSC3 HTR3C 25348397 N/A physical interaction ComPPI
TUSC3 PABIR2 25348397 N/A physical interaction ComPPI
TUSC3 LIN54 25348397 N/A physical interaction ComPPI
TUSC3 NDRG3 25348397 N/A physical interaction ComPPI
TUSC3 RNF185 25348397 N/A physical interaction ComPPI

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