Gene Information gene info

  1. Home

GENE：ZAP70

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ZAP70
FullNmae zeta chain of T cell receptor associated protein kinase 70
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12858
EnsembleID ENSG00000115085
Uniprot P43403

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ZAP70 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ZAP70 GO:0001772,GO:0001784,GO:0001784,GO:0002250,GO:0004713,GO:0004713,GO:0004713,GO:0004715,GO:0004715,GO:0004715,GO:0005102,GO:0005515,GO:0005524,GO:0005737,GO:0005829,GO:0005886,GO:0005886,GO:0005911,GO:0006468,GO:0006468,GO:0006468,GO:0006955,GO:0007169,GO:0018108,GO:0018108,GO:0019722,GO:0030154,GO:0030217,GO:0031234,GO:0031234,GO:0035556,GO:0042101,GO:0042110,GO:0042113,GO:0043366,GO:0045059,GO:0045060,GO:0045087,GO:0045121,GO:0045582,GO:0046638,GO:0046641,GO:0050850,GO:0050852,GO:0050852,GO:0070489,GO:0072678

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ZAP70 hsa:7535 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
ZAP70 hsa:7535 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
ZAP70 hsa:7535 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
ZAP70 hsa:7535 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
ZAP70 hsa:7535 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
ZAP70 hsa:7535 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
ZAP70 hsa:7535 path:hsa05135 Yersinia infection - Homo sapiens (human)
ZAP70 hsa:7535 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)
ZAP70 hsa:7535 path:hsa05340 Primary immunodeficiency - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CD247 ZAP70 10358158 10358164 10562324 10925299 11353765 11438547 11449354 11875494 12393695 12415267 12731048 12811837 15081523 15099567 15268851 15735648 16713974 17371980 18768831 20435894 20814939 21059766 2139103 23109003 23414611 23508573 23620508 23886063 24378531 24445665 26192618 7523143 7600293 8344348 8478617 8551221 8642247 9603467 9625766 9738502 interaction type,chemical activation reaction N/A ACSN,SignaLink
ZAP70 TUBGCP2 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
ZAP70 TUBGCP3 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
ZAP70 TUBGCP4 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
ZAP70 TUBGCP5 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
ZAP70 TUBGCP6 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
ZAP70 PXN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
CD4 ZAP70 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 26192618 3263576 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
LCK ZAP70 10318843 10652356 12731048 12740575 15144186 17544292 19290918 20814939 21127503 22513334 23331499 23620508 26192618 3263576 7961936 8478617 8798643 8986721 9438848 9685404 9738502 9751747 interaction type,stimulation N/A ACSN,SignaLink
CBLC ZAP70 12415267 26192618 9671496 interaction type N/A ACSN
ZAP70 CD6 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
ZAP70 LAT 12415267 12731048 15084594 15735648 17371980 20814939 23109003 23620508 26192618 7600293 8642247 interaction type,chemical activation reaction N/A ACSN,SignaLink
ZAP70 PLCG1 10562324 10925299 11353765 11438547 11709089 11875494 12415267 12731048 12811837 12941616 15735648 16713974 17371980 20435894 20814939 21059766 23109003 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type,chemical activation reaction N/A ACSN,SignaLink
ZAP70 GRB2 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
ZAP70 GRAP 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
ZAP70 GAB2 10358138 10562324 10849428 10982827 11353765 11447289 11572860 12138178 12415267 12640133 12707331 12731048 15240681 15699106 15713798 15735648 16212621 17371980 19833085 19909365 20814939 21059766 23109003 23414611 23620508 23886063 26192618 7600293 8478617 8642247 9625766 9738502 9751747 interaction type,chemical activation reaction N/A ACSN,SignaLink
ZAP70 LCP2 11323691 12415267 12640133 12731048 15286727 15735648 17371980 20814939 23109003 23620508 26192618 7600293 8642247 interaction type,chemical activation reaction N/A ACSN,SignaLink
ZAP70 VAV2 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
ZAP70 VAV3 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
CBL ZAP70 10358158 11133830 11353765 15169881 15268851 18835194 20189481 23109003 26192618 interaction type,inhibition N/A ACSN,SignaLink
FCER1G ZAP70 10358164 10562324 10925299 11353765 11438547 11449354 11875494 12393695 12415267 12731048 12811837 15081523 15099567 15735648 16713974 17371980 18768831 20435894 20814939 21059766 2139103 23414611 23508573 23620508 23886063 24378531 24445665 26192618 7523143 7600293 8344348 8478617 8551221 8642247 9603467 9625766 9738502 interaction type N/A ACSN
KIR2DS2 ZAP70 11015446 12731048 20814939 23715743 24586048 26192618 9490415 9625766 9655483 interaction type N/A ACSN
ITGA4 ZAP70 12626562 12731048 19161977 19454690 19487819 20814939 22470492 26192618 9003039 9456329 9763606 9973479 interaction type N/A ACSN
ITGB1 ZAP70 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 26192618 9003039 9456329 9763606 9973479 interaction type N/A ACSN
FN1 ZAP70 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 26192618 9003039 9456329 9763606 9973479 interaction type N/A ACSN
ITGA5 ZAP70 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 26192618 9003039 9456329 9763606 9973479 interaction type N/A ACSN
ZAP70 MUC1 14766232 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
PIK3CG ZAP70 17998387 23180781 physical association anti tag coimmunoprecipitation InnateDB
ZAP70 LCK 17998387 23180781 physical association anti tag coimmunoprecipitation InnateDB
GNA11 ZAP70 17998387 23180781 physical association anti tag coimmunoprecipitation InnateDB
ZAP70 CXCR4 17998387 23180781 physical association anti tag coimmunoprecipitation InnateDB
ZAP70 CD3G 11493682 23180781 physical association anti tag coimmunoprecipitation InnateDB
ZAP70 CD247 23180781 7522230 physical association anti tag coimmunoprecipitation InnateDB
ZAP70 CD33 12763134 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 ZAP70 10458769 12763134 23109003 23180781 8638162 inhibition,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
APP ZAP70 21832049 23180781 physical association protein array InnateDB
ZAP70 ZAP70 10037717 11828374 15735648 16049944 26467481 7961936 8756661 phosphorylation reaction,up-regulates activity,down-regulates N/A Signor
ZAP70 CBLB 10074432 23109003 8798643 chemical activation reaction N/A SignaLink
ZAP70 CBL 10779765 11133830 23109003 8798643 chemical activation reaction N/A SignaLink
ZAP70 MAPK14 15735649 23109003 chemical activation reaction N/A SignaLink
ZAP70 VAV1 11859198 14757747 15751964 23109003 chemical activation reaction N/A SignaLink
ZAP70 SH3BP2 15751964 23109003 chemical activation reaction N/A SignaLink
ZAP70 CRK 10419455 23109003 chemical activation reaction N/A SignaLink
ZAP70 ITK 11709089 15084594 23109003 chemical activation reaction N/A SignaLink

Source Target Pmid Interactiontype Methods Database
CRK ZAP70 20005715 interaction type N/A PSP,SignaLink
DBNL ZAP70 20005715 interaction type N/A PSP
GRB2 ZAP70 20005715 interaction type N/A PSP
LAT ZAP70 20005715 interaction type N/A PSP
LAX1 ZAP70 20005715 interaction type N/A PSP,SignaLink
LCP2 ZAP70 20005715 interaction type N/A PSP
PAG1 ZAP70 20005715 interaction type N/A PSP
SH2B3 ZAP70 20005715 interaction type N/A PSP,SignaLink
SH3BP2 ZAP70 11390470 18988627 20005715 interaction type N/A PSP,SignaLink
SHB ZAP70 12084069 18988627 20005715 interaction type N/A PSP,SignaLink
SHC1 ZAP70 20005715 interaction type N/A PSP
SIT1 ZAP70 20005715 interaction type N/A PSP
SLA2 ZAP70 11891219 18988627 20005715 interaction type N/A PSP,SignaLink
TYROBP ZAP70 20005715 interaction type N/A PSP
GRB2 ZAP70 18988627 20005715 21071413 7629168 N/A N/A SignaLink
PAG1 ZAP70 10790433 10790433 18988627 20005715 20005715 21071413 N/A N/A SignaLink
LCP2 ZAP70 20005715 20005715 21071413 9047237 N/A N/A SignaLink
SHC1 ZAP70 15688026 18988627 20005715 20005715 21071413 7961936 8761298 9685404 9685404 9685404 N/A N/A SignaLink
DBNL ZAP70 14557276 14557276 14557276 20005715 20005715 21071413 N/A N/A SignaLink
LAT ZAP70 11368773 12186560 20005715 20005715 21071413 N/A N/A SignaLink
SIT1 ZAP70 10209036 18988627 20005715 20005715 N/A N/A SignaLink
TYROBP ZAP70 18988627 20005715 20005715 21071413 9490415 9490415 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
E2F4 ZAP70 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ZAP70 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ZAP70 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ZAP70 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ZAP70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ZAP70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ZAP70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ZAP70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ZAP70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ZAP70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CREM ZAP70 16237091 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 ZAP70 21205967 rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS000027352D ZAP70 21205967 rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS00002C7B2B ZAP70 21205967 rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS00000EED18 ZAP70 21205967 21566225 25416803 mrna cleavage,inhibition experimental interaction detection,miRNA interference luciferase reporter assay TarBase
URS000027352D ZAP70 21205967 25416803 mrna cleavage,inhibition experimental interaction detection,miRNA interference luciferase reporter assay TarBase
URS00002C7B2B ZAP70 21205967 25416803 mrna cleavage,inhibition experimental interaction detection,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
ZAP70 GAB2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
ZAP70 ZAP70 22135298 phosphorylation N/A PhosphoSite
ZAP70 LCP2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
ZAP70 DBNL 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
ZAP70 THEMIS 22135298 phosphorylation N/A PhosphoSite
ZAP70 MAPK14 22135298 phosphorylation N/A PhosphoSite
ZAP70 DUSP3 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
ABL1 ZAP70 22135298 phosphorylation N/A PhosphoSite
LCK ZAP70 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
CBLB ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 CBLB 25361965 interaction type N/A PTMCode2
CD4 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 CD4 25361965 interaction type N/A PTMCode2
SLA2 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 SLA2 25361965 interaction type N/A PTMCode2
CBL ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 CBL 25361965 interaction type N/A PTMCode2
ZAP70 CRK 25361965 interaction type N/A PTMCode2
CRK ZAP70 25361965 interaction type N/A PTMCode2
GAB2 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 DEF6 25361965 interaction type N/A PTMCode2
DEF6 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 NFAM1 25361965 interaction type N/A PTMCode2
NFAM1 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 HSP90AA1 25361965 interaction type N/A PTMCode2
HSP90AA1 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 LCK 25361965 interaction type N/A PTMCode2
ZAP70 CD5 25361965 interaction type N/A PTMCode2
CD5 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 WIPF1 25361965 interaction type N/A PTMCode2
WIPF1 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 CD3E 25361965 interaction type N/A PTMCode2
CD3E ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 CD247 25361965 interaction type N/A PTMCode2
CD247 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 LAX1 25361965 interaction type N/A PTMCode2
LAX1 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 PTPRC 25361965 interaction type N/A PTMCode2
PTPRC ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 FCRL3 25361965 interaction type N/A PTMCode2
FCRL3 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 FYN 25361965 interaction type N/A PTMCode2
FYN ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 SHB 25361965 interaction type N/A PTMCode2
SHB ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 CARD11 25361965 interaction type N/A PTMCode2
CARD11 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 SHC1 25361965 interaction type N/A PTMCode2
SHC1 ZAP70 25361965 interaction type N/A PTMCode2
DBNL ZAP70 25361965 interaction type N/A PTMCode2
LCP2 ZAP70 25361965 interaction type N/A PTMCode2
DUSP3 ZAP70 25361965 interaction type N/A PTMCode2
PAG1 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 PAG1 25361965 interaction type N/A PTMCode2
SIT1 ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 SIT1 25361965 interaction type N/A PTMCode2
TYROBP ZAP70 25361965 interaction type N/A PTMCode2
ZAP70 TYROBP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LCP2 ZAP70 10660534 14525934 24234451 24584089 25348397 8702662 9047237 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
DEF6 ZAP70 12648457 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LAT ZAP70 11368773 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
TUBB ZAP70 25348397 N/A physical interaction,in vitro,in vivo ComPPI
PTPN6 ZAP70 10458769 14525934 25348397 8638162 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CRK ZAP70 10419455 14525934 16339550 24234451 25348397 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CD4 ZAP70 25348397 N/A physical interaction ComPPI
CBL ZAP70 10074432 11133830 14525934 22266821 24234451 25348397 8798643 physical association experimental interaction detection,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
VAV1 ZAP70 14525934 16339550 24234451 25348397 7798261 9151714 association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PRLR ZAP70 10221598 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SHB ZAP70 12084069 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SLA ZAP70 10449770 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTK2B ZAP70 10867021 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SH3BP2 ZAP70 11390470 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CBLB ZAP70 10074432 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PAG1 ZAP70 10790433 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KIT ZAP70 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
PIK3R1 ZAP70 25348397 N/A physical interaction ComPPI
FCGR3A ZAP70 25348397 N/A in vitro ComPPI
CD38 ZAP70 25348397 N/A physical interaction ComPPI
SH2B3 ZAP70 14525934 25348397 9169414 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK ZAP70 10318843 10556826 14525934 15144186 16461343 24234451 25348397 7961936 8798643 9685404 phosphorylation reaction,association,physical association anti tag coimmunoprecipitation,experimental interaction detection,far western blotting,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
SHC1 ZAP70 14525934 15688026 24234451 25348397 7961936 8761298 9685404 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SOS1 ZAP70 14525934 25348397 7629168 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
GAB2 ZAP70 11572860 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CBLC ZAP70 25348397 N/A physical interaction ComPPI
GRB2 ZAP70 14525934 25348397 7629168 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CD5 ZAP70 14525934 25348397 9378960 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ZAP70 CD247 10704231 10752619 14525934 15832366 21957439 24234451 25348397 7509083 7528772 8366117 8648092 8901551 9185620 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,fluorescent resonance energy transfer,isothermal titration calorimetry,peptide array,pull down,surface plasmon resonance,physical interaction,enzymatic study,in vivo ComPPI,HPRD,IntAct
ZAP70 TUBA4A 14525934 25348397 8530437 N/A experimental interaction detection,in vivo ComPPI,HPRD
ZAP70 DUSP3 12447358 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ZAP70 TYROBP 14525934 25348397 9490415 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ZAP70 SIT1 10209036 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ZAP70 SLAMF6 14525934 25348397 8756661 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ZAP70 SLA2 11891219 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ZAP70 DBNL 14525934 14557276 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ZAP70 FCRL3 12051764 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ZAP70 CD3E 11855827 14525934 24234451 25348397 7761456 8366117 association experimental interaction detection,pull down,surface plasmon resonance,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
ZAP70 NFAM1 14525934 15143214 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ZAP70 IFNAR1 14525934 25348397 9403695 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ZAP70 CD79B 12393534 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ZAP70 WIPF1 12504004 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ZAP70 CARD11 12154360 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ZAP70 LAX1 12359715 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ZAP70 PTPN22 14525934 16461343 24234451 25348397 dephosphorylation reaction,association experimental interaction detection,pull down,physical interaction,phosphatase assay,in vivo ComPPI,HPRD,IntAct
ZAP70 FYN 14525934 25348397 7760813 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ZAP70 RASA1 14525934 25348397 7760813 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ZAP70 PTPRC 25348397 N/A in vitro ComPPI
ZAP70 ABL1 14525934 25348397 7760813 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ZAP70 ACP1 11976341 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ZAP70 PLCG1 14525934 25348397 7629168 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ZAP70 TUBA1B 25348397 N/A physical interaction ComPPI
ZAP70 TUBA1A 25348397 N/A physical interaction ComPPI
ZAP70 HSPA4 25348397 N/A physical interaction ComPPI
ZAP70 APP 25348397 N/A physical interaction ComPPI
ZAP70 EGFR 16273093 24234451 24658140 25348397 physical association protein array,ubiquitin reconstruction,physical interaction ComPPI,IntAct
ZAP70 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
ZAP70 NDUFB8 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ZAP70 ANAPC11 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ZAP70 NR0B2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ZAP70 ASB3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ZAP70 CSK 25348397 N/A physical interaction ComPPI
ZAP70 PEAR1 25348397 N/A physical interaction ComPPI
ZAP70 USP12 25348397 N/A physical interaction ComPPI
ZAP70 RNF41 25348397 N/A physical interaction ComPPI
ZAP70 USP2 25348397 N/A physical interaction ComPPI
ZAP70 HSP90AA1 16888650 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ZAP70 MET 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
ZAP70 HAVCR2 24234451 25348397 26492563 association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
ZAP70 LRRK2 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
ZAP70 DAPK1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
ZAP70 ZAP70 10037717 14525934 15144186 7961936 8798643 N/A experimental interaction detection HPRD
PTPN3 ZAP70 14525934 14672952 15588985 N/A experimental interaction detection HPRD
ZAP70 MUC1 14525934 14766232 N/A experimental interaction detection HPRD
ZAP70 TUBB2A 14525934 8530437 N/A experimental interaction detection HPRD
SLC4A1 ZAP70 10358158 27898060 8798454 N/A N/A OmniPath
LCK ZAP70 10037717 10318843 10556826 11270871 11514605 11514606 11976341 12522270 15100278 15144186 15592455 15699074 16049944 16094384 16339550 16461343 16501569 17579062 17998387 26237552 27898060 7539035 7642520 7781602 7961936 8756661 8798643 9685404 inhibition,stimulant N/A OmniPath
CXCR4 ZAP70 17998387 27898060 N/A N/A OmniPath
ZAP70 LAT 11368773 11395491 12186560 12496416 15029250 16906159 23460737 23514740 23901140 24642916 27898060 stimulant N/A OmniPath
PTPN6 ZAP70 10458769 12763134 27898060 8638162 inhibition,stimulant N/A OmniPath
ZAP70 PTPN6 10458769 12763134 27898060 8638162 N/A N/A OmniPath
ZAP70 MAPK14 10781613 15674326 15735648 15735649 15972258 27898060 stimulant N/A OmniPath
ZAP70 SHC1 10482988 10764799 10816433 10896916 10921922 11075717 12237775 15688026 16497976 17016520 17389395 18452278 18578522 18669648 19651622 19664994 19901323 20068231 20230923 23267066 27898060 7961936 8761298 9096689 9121430 9388490 9446569 9685404 9710204 9741627 stimulant N/A OmniPath
ZAP70 MUC1 14766232 27898060 stimulant N/A OmniPath
ZAP70 LCP2 10660534 12190313 12817019 15388330 15714472 17353368 25452106 27898060 8702662 8892604 9047237 stimulant N/A OmniPath
ZAP70 VAV2 27898060 7798261 stimulant N/A OmniPath
PTCRA ZAP70 1717999 27898060 stimulant N/A OmniPath
ZAP70 GAB2 11334882 11572860 27898060 stimulant N/A OmniPath
ZAP70 TUBA1A 27898060 8530437 8617742 stimulant N/A OmniPath
ZAP70 DBNL 14557276 27898060 stimulant N/A OmniPath
PIK3CG ZAP70 17998387 27898060 N/A N/A OmniPath
ZAP70 CDC37 12930845 15082798 27898060 N/A N/A OmniPath
ZAP70 DUSP3 12447358 27898060 stimulant N/A OmniPath
ZAP70 HSPB8 11342557 27898060 N/A N/A OmniPath
ACP1 ZAP70 11976341 27898060 inhibition N/A OmniPath
ZAP70 SH2B3 27898060 9169414 stimulant N/A OmniPath
PTPN22 ZAP70 16461343 27898060 inhibition N/A OmniPath
ZAP70 PIN4 12860119 27898060 N/A N/A OmniPath
ZAP70 SIT1 10209036 11433379 27898060 N/A N/A OmniPath

Visualization










  Return