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GENE：HGD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HGD
FullNmae homogentisate 1,2-dioxygenase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4892
EnsembleID ENSG00000113924
Uniprot Q93099

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HGD immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HGD GO:0004411,GO:0004411,GO:0005515,GO:0005829,GO:0006559,GO:0006559,GO:0006572,GO:0042802,GO:0046872,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HGD hsa:3081 path:hsa00350 Tyrosine metabolism - Homo sapiens (human)
HGD hsa:3081 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 HGD 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 HGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 HGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 HGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 HGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 HGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR HGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 HGD 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 HGD 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
HGD TERF1 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
HGD CLDN7 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HGD GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HGD NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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