GENE:KIF3B
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | KIF3B |
| FullNmae | kinesin family member 3B |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:6320 |
| EnsembleID | ENSG00000101350 |
| Uniprot | O15066 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| KIF3B | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| KIF3B | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| KIF3B | GO:0003777,GO:0005515,GO:0005524,GO:0005813,GO:0005829,GO:0005871,GO:0005873,GO:0005874,GO:0005876,GO:0005929,GO:0005929,GO:0007018,GO:0007052,GO:0007100,GO:0007368,GO:0008017,GO:0008089,GO:0008574,GO:0015630,GO:0016020,GO:0016192,GO:0016887,GO:0016939,GO:0030425,GO:0030496,GO:0031267,GO:0032467,GO:0032839,GO:0036372,GO:0042073,GO:0043197,GO:0060271,GO:0070062,GO:0072383,GO:0090307,GO:0097542,GO:0098971,GO:0120170,GO:1904115 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| KIF3B | hsa:9371 | path:hsa04814 | Motor proteins - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| KIF3A | KIF3B | 11208056 11226259 11449277 14603322 15618519 15852005 17641202 18497258 18820483 19081070 19565474 19718039 19853559 20215540 20375059 20643644 20956384 21602792 23031257 26192618 | association | N/A | ACSN |
| SMO | KIF3B | 11208056 11226259 11449277 14603322 15618519 17641202 18497258 18820483 19081070 19565474 19853559 20215540 20375059 23031257 26192618 | interaction type | N/A | ACSN |
| RAB23 | KIF3B | 11449277 18497258 20375059 26192618 | interaction type | N/A | ACSN |
| KIF3B | SUFU | 11208056 14603322 20643644 20956384 26192618 | interaction type | N/A | ACSN |
| KIF3B | ULK3 | 11208056 14603322 20643644 20956384 26192618 | interaction type | N/A | ACSN |
| APP | KIF3B | 21832049 23180781 | physical association | protein array | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | KIF3B | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | KIF3B | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | KIF3B | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | KIF3B | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | KIF3B | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | KIF3B | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | KIF3B | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | KIF3B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | KIF3B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | KIF3B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | KIF3B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | KIF3B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | KIF3B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | KIF3B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | KIF3B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000005481D | KIF3B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000153377 | KIF3B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000016D2D4 | KIF3B | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000171CD1 | KIF3B | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018C928 | KIF3B | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | KIF3B | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | KIF3B | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000236310 | KIF3B | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005586D0 | KIF3B | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000036AFF1 | KIF3B | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000050CCE0 | KIF3B | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000017CCCB | KIF3B | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A6D0C | KIF3B | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029D9F1 | KIF3B | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002233F4 | KIF3B | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002971AB | KIF3B | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000753AD | KIF3B | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BE495 | KIF3B | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000020579D | KIF3B | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000004BACE | KIF3B | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000585553 | KIF3B | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LMO4 | KIF3B | 14525934 15231748 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| RAB4A | KIF3B | 12832475 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| RAD21 | KIF3B | 25348397 | N/A | physical interaction | ComPPI |
| SLC9A3R2 | KIF3B | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| NTRK1 | KIF3B | 25348397 | N/A | physical interaction | ComPPI |
| KIFAP3 | KIF3B | 14525934 16298999 24234451 25348397 26496610 27173435 9506951 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification,inference by socio-affinity scoring,two hybrid | ComPPI,HPRD,IntAct |
| MAP3K10 | KIF3B | 14525934 25348397 9427749 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD |
| AKAP12 | KIF3B | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| MAP3K11 | KIF3B | 25348397 | N/A | physical interaction | ComPPI |
| KIF3B | IFT20 | 12821668 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| KIF3B | RAB5A | 25348397 | N/A | physical interaction | ComPPI |
| KIF3B | VHL | 25348397 | N/A | physical interaction | ComPPI |
| KIF3B | KIF3A | 14525934 24234451 25348397 26496610 27173435 7559760 | association,physical association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,tandem affinity purification,inference by socio-affinity scoring | ComPPI,HPRD,IntAct |
| KIF3B | APP | 25348397 | N/A | physical interaction | ComPPI |
| KIF3B | LMO2 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| KIF3B | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| KIF3B | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| KIF3B | RANBP2 | 25348397 | N/A | physical interaction | ComPPI |
| KIF3B | KIFBP | 25348397 | N/A | physical interaction | ComPPI |
| KIF3B | RGS20 | 25348397 | N/A | physical interaction | ComPPI |
| KIF3B | STK4 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| KIF3B | DYRK2 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| KIF3B | SAV1 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| KIF3B | KIF3C | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| KIF3B | PSMC5 | 24234451 25348397 27173435 | association,physical association | physical interaction,tandem affinity purification,inference by socio-affinity scoring | ComPPI,IntAct |
| KIF3B | STK3 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| KIF3B | ARHGEF10 | 19635168 24234451 25348397 27898060 | association,physical association | anti tag coimmunoprecipitation,two hybrid,fluorescence microscopy | ComPPI,IntAct,OmniPath |
| KIF3B | CLCN5 | 19940036 24234451 25348397 | colocalization,physical association | anti tag coimmunoprecipitation,two hybrid,pull down,confocal microscopy | ComPPI,IntAct |
| NEDD4L | KIF3B | 25348397 | N/A | physical interaction | ComPPI |
