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GENE：DCAF4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DCAF4
FullNmae DDB1 and CUL4 associated factor 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20229
EnsembleID ENSG00000119599
Uniprot Q8WV16

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DCAF4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DCAF4 GO:0005515,GO:0005654,GO:0016567,GO:0080008,GO:0080008

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NEDD8 DCAF4 21145461 23180781 physical association anti tag coimmunoprecipitation InnateDB
CUL4A DCAF4 21145461 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 DCAF4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 DCAF4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C DCAF4 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DCAF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DCAF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DCAF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DCAF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DCAF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DCAF4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000381CEC DCAF4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002F74F1 DCAF4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 DCAF4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 DCAF4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000A057E DCAF4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000035CC3E DCAF4 22100165 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PIM1 DCAF4 25348397 N/A physical interaction ComPPI
COPS5 DCAF4 25348397 N/A physical interaction ComPPI
USP7 DCAF4 25348397 N/A physical interaction ComPPI
COPS2 DCAF4 25348397 N/A physical interaction ComPPI
CUL4B DCAF4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL4A DCAF4 25348397 N/A physical interaction ComPPI
GLMN DCAF4 25348397 N/A physical interaction ComPPI
COPS3 DCAF4 25348397 N/A physical interaction ComPPI
COPS4 DCAF4 25348397 N/A physical interaction ComPPI
GPS1 DCAF4 25348397 N/A physical interaction ComPPI
COPS6 DCAF4 25348397 N/A physical interaction ComPPI
COPS7A DCAF4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS8 DCAF4 25348397 N/A physical interaction ComPPI
DDB1 DCAF4 19966799 24234451 25348397 N/A x-ray crystallography,physical interaction ComPPI,IntAct
NUDC DCAF4 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
COPS7B DCAF4 25348397 N/A physical interaction ComPPI
POLR2F DCAF4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PFDN2 DCAF4 25348397 N/A physical interaction ComPPI
CLUH DCAF4 25348397 N/A physical interaction ComPPI
HSPD1 DCAF4 25348397 N/A physical interaction ComPPI
DKC1 DCAF4 25348397 N/A physical interaction ComPPI
SOX30 DCAF4 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CCT2 DCAF4 25348397 N/A physical interaction ComPPI
CCT3 DCAF4 25348397 N/A physical interaction ComPPI
LONP1 DCAF4 25348397 N/A physical interaction ComPPI
DCAF4 AP5M1 25348397 N/A physical interaction ComPPI
DCAF4 IMPDH1 25348397 N/A physical interaction ComPPI
NEUROG3 DCAF4 25348397 N/A physical interaction ComPPI

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