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GENE：GTF2E2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GTF2E2
FullNmae general transcription factor IIE subunit 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4651
EnsembleID ENSG00000197265
Uniprot P29084

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GTF2E2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GTF2E2 GO:0001097,GO:0003677,GO:0003723,GO:0005515,GO:0005654,GO:0005654,GO:0005669,GO:0005673,GO:0005829,GO:0006366,GO:0006367,GO:0016251

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GTF2E2 hsa:2961 path:hsa03022 Basal transcription factors - Homo sapiens (human)
GTF2E2 hsa:2961 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GTF2E2 MCC 21988832 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP GTF2E2 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GTF2E2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 GTF2E2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 GTF2E2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GTF2E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GTF2E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GTF2E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GTF2E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GTF2E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GTF2E2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001012BC GTF2E2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005E6F45 GTF2E2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000013D17D GTF2E2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 GTF2E2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 GTF2E2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F GTF2E2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 GTF2E2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 GTF2E2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 GTF2E2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001A405B GTF2E2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 GTF2E2 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MNAT1 GTF2E2 25361965 interaction type N/A PTMCode2
GTF2E2 MNAT1 25361965 interaction type N/A PTMCode2
CCNH GTF2E2 25361965 interaction type N/A PTMCode2
GTF2E2 CCNH 25361965 interaction type N/A PTMCode2
POLR2B GTF2E2 25361965 interaction type N/A PTMCode2
GTF2E2 POLR2B 25361965 interaction type N/A PTMCode2
GTF2E1 GTF2E2 25361965 interaction type N/A PTMCode2
GTF2E2 GTF2E1 25361965 interaction type N/A PTMCode2
POLR2E GTF2E2 25361965 interaction type N/A PTMCode2
GTF2E2 POLR2E 25361965 interaction type N/A PTMCode2
GTF2E2 GTF2B 25361965 interaction type N/A PTMCode2
GTF2B GTF2E2 25361965 interaction type N/A PTMCode2
GTF2E2 GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 GTF2E2 25361965 interaction type N/A PTMCode2
ATF7IP GTF2E2 25361965 interaction type N/A PTMCode2
GTF2E2 ATF7IP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CCNH GTF2E2 11113176 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
OIP5 GTF2E2 25348397 N/A physical interaction ComPPI
MIS18A GTF2E2 25348397 N/A physical interaction ComPPI
TPP2 GTF2E2 25348397 N/A physical interaction ComPPI
NUP62 GTF2E2 11113176 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GTF2A1 GTF2E2 11509574 14525934 25348397 9618479 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ERCC3 GTF2E2 14525934 25348397 8152490 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GTF2B GTF2E2 11113176 12665589 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
EXOC8 GTF2E2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSP90AB1 GTF2E2 25348397 N/A physical interaction ComPPI
PDCD10 GTF2E2 25348397 N/A physical interaction ComPPI
TACC3 GTF2E2 25348397 N/A physical interaction ComPPI
PICK1 GTF2E2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBP GTF2E2 11113176 14525934 25348397 9677423 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PTPN11 GTF2E2 25348397 N/A physical interaction ComPPI
SND1 GTF2E2 25348397 N/A physical interaction,in vitro,in vivo ComPPI
PPP1R8 GTF2E2 25348397 N/A physical interaction ComPPI
JUN GTF2E2 25348397 N/A physical interaction ComPPI
GTF2F2 GTF2E2 11113176 14525934 25348397 9677423 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CPNE1 GTF2E2 25348397 N/A physical interaction ComPPI
EIF5B GTF2E2 25348397 N/A physical interaction ComPPI
SLC9A3R2 GTF2E2 25348397 N/A physical interaction ComPPI
GTF2H1 GTF2E2 12665589 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
DUSP3 GTF2E2 25348397 N/A physical interaction ComPPI
TLN1 GTF2E2 25348397 N/A physical interaction ComPPI
SIN3A GTF2E2 25348397 N/A physical interaction ComPPI
FEN1 GTF2E2 25348397 N/A physical interaction ComPPI
HDLBP GTF2E2 25348397 N/A physical interaction ComPPI
DBNL GTF2E2 25348397 N/A physical interaction ComPPI
UBR5 GTF2E2 25348397 N/A physical interaction ComPPI
TPR GTF2E2 25348397 N/A physical interaction ComPPI
KLF5 GTF2E2 14525934 25348397 9089417 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
UBA6 GTF2E2 25348397 N/A physical interaction ComPPI
EXOC4 GTF2E2 25348397 N/A physical interaction ComPPI
XPA GTF2E2 14525934 25348397 27898060 7876263 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
MNAT1 GTF2E2 11113176 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ZRANB2 GTF2E2 25348397 N/A physical interaction ComPPI
MDM2 GTF2E2 14525934 25348397 9271120 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TSFM GTF2E2 25348397 N/A physical interaction ComPPI
SF3A1 GTF2E2 25348397 N/A physical interaction ComPPI
GTF2E2 GTF2E1 11113176 12665589 14525934 16547462 24234451 25348397 9677423 physical association cross-linking study,electron microscopy,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
GTF2E2 GTF2F1 11113176 14525934 25348397 9677423 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GTF2E2 SUPT16H 10792464 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
GTF2E2 ERCC6 14525934 25348397 8999876 N/A experimental interaction detection,in vitro ComPPI,HPRD
GTF2E2 POLR2A 25348397 N/A physical interaction ComPPI
GTF2E2 FOS 25348397 N/A physical interaction ComPPI
GTF2E2 HNRNPA1 25348397 N/A physical interaction ComPPI
GTF2E2 MTA2 25348397 N/A physical interaction ComPPI
GTF2E2 DNM2 25348397 N/A physical interaction ComPPI
GTF2E2 ATF7IP 10777215 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
GTF2E2 APP 25348397 N/A physical interaction ComPPI
GTF2E2 CDK7 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GTF2E2 MMS19 25348397 N/A physical interaction ComPPI
GTF2E2 MCC 21988832 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GTF2E2 PBDC1 25348397 N/A physical interaction ComPPI
GTF2E2 SEC24D 25348397 N/A physical interaction ComPPI
GTF2E2 SHMT2 25348397 N/A physical interaction ComPPI
GTF2E2 MOV10 25348397 N/A physical interaction ComPPI
GTF2E2 NXF1 25348397 N/A physical interaction ComPPI
GTF2E2 EEF1G 25348397 N/A physical interaction ComPPI
GTF2E2 SART3 25348397 N/A physical interaction ComPPI
GTF2E2 EIF2A 25348397 N/A physical interaction ComPPI
GTF2E2 SBDS 25348397 N/A physical interaction ComPPI
GTF2E2 CYRIB 25348397 N/A physical interaction ComPPI
GTF2E2 DNAJC2 25348397 N/A physical interaction ComPPI
GTF2E2 PHPT1 25348397 N/A physical interaction ComPPI
GTF2E2 SLK 25348397 N/A physical interaction ComPPI
GTF2E2 NARS1 25348397 N/A physical interaction ComPPI
GTF2E2 HDGFL2 25348397 N/A physical interaction ComPPI
GTF2E2 NAA15 25348397 N/A physical interaction ComPPI
GTF2E2 VRK1 25348397 N/A physical interaction ComPPI
GTF2E2 TOMM34 25348397 N/A physical interaction ComPPI
GTF2E2 UBE2T 25348397 N/A physical interaction ComPPI
GTF2E2 HIBCH 25348397 N/A physical interaction ComPPI
GTF2E2 ACTBL2 25348397 N/A physical interaction ComPPI
GTF2E2 RBM12 25348397 N/A physical interaction ComPPI
GTF2E2 LYPLA1 25348397 N/A physical interaction ComPPI
GTF2E2 FARSB 25348397 N/A physical interaction ComPPI
GTF2E2 MCTS1 25348397 N/A physical interaction ComPPI
GTF2E2 STX7 25348397 N/A physical interaction ComPPI
GTF2E2 BLVRB 25348397 N/A physical interaction ComPPI
GTF2E2 AK4 25348397 N/A physical interaction ComPPI
GTF2E2 LRRC40 25348397 N/A physical interaction ComPPI
GTF2E2 ETF1 25348397 N/A physical interaction ComPPI
GTF2E2 MDC1 25348397 N/A physical interaction ComPPI
GTF2E2 IBA57 25348397 N/A physical interaction ComPPI
GTF2E2 HMGN5 25348397 N/A physical interaction ComPPI
GTF2E2 RPRD1A 25348397 N/A physical interaction ComPPI
GTF2E2 ZMPSTE24 25348397 N/A physical interaction ComPPI
GTF2E2 PMVK 25348397 N/A physical interaction ComPPI
GTF2E2 UGP2 25348397 N/A physical interaction ComPPI
GTF2E2 GINS4 25348397 N/A physical interaction ComPPI
GTF2E2 GINS1 25348397 N/A physical interaction ComPPI
GTF2E2 EIF3J 25348397 N/A physical interaction ComPPI
GTF2E2 WDHD1 25348397 N/A physical interaction ComPPI
GTF2E2 CMTR1 25348397 N/A physical interaction ComPPI
GTF2E2 PYM1 25348397 N/A physical interaction ComPPI
GTF2E2 GINS3 25348397 N/A physical interaction ComPPI
GTF2E2 CSTF3 25348397 N/A physical interaction ComPPI
GTF2E2 ACAA1 25348397 N/A physical interaction ComPPI
GTF2E2 EFHD2 25348397 N/A physical interaction ComPPI
GTF2E2 ADSL 25348397 N/A physical interaction ComPPI
GTF2E2 MESD 25348397 N/A physical interaction ComPPI
GTF2E2 SNX5 25348397 N/A physical interaction ComPPI
GTF2E2 GMPS 25348397 N/A physical interaction ComPPI
GTF2E2 CHORDC1 25348397 N/A physical interaction ComPPI
GTF2E2 DIS3 25348397 N/A physical interaction ComPPI
GTF2E2 PPME1 25348397 N/A physical interaction ComPPI
GTF2E2 SPRYD4 25348397 N/A physical interaction ComPPI
GTF2E2 TOP1 25348397 N/A physical interaction ComPPI
GTF2E2 YARS1 25348397 N/A physical interaction ComPPI
GTF2E2 PACSIN2 25348397 N/A physical interaction ComPPI
GTF2E2 CSTF1 25348397 N/A physical interaction ComPPI
GTF2E2 CAB39 25348397 N/A physical interaction ComPPI
GTF2E2 SRRT 25348397 N/A physical interaction ComPPI
GTF2E2 TRIM25 25348397 N/A physical interaction ComPPI
GTF2E2 LNX1 25348397 N/A physical interaction ComPPI
GTF2E2 KAT5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GTF2E2 POLR2E 24234451 25348397 27193682 physical association electron tomography ComPPI,IntAct
GTF2E2 ERCC2 24234451 25348397 27193682 physical association electron tomography ComPPI,IntAct
GTF2E2 CDK8 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
H3C1 GTF2E2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EEF1A2 GTF2E2 25348397 N/A physical interaction ComPPI
UBLCP1 GTF2E2 25348397 N/A physical interaction ComPPI
RNF20 GTF2E2 25348397 N/A physical interaction ComPPI
HSCB GTF2E2 24234451 24606901 25348397 physical association two hybrid ComPPI,IntAct
H1-2 GTF2E2 24234451 30021884 physical association cross-linking study IntAct

Visualization










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