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GENE：HAS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HAS2
FullNmae hyaluronan synthase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4819
EnsembleID ENSG00000170961
Uniprot Q92819

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HAS2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HAS2 GO:0000139,GO:0001570,GO:0001822,GO:0005515,GO:0005764,GO:0005789,GO:0005794,GO:0005886,GO:0008284,GO:0010838,GO:0014911,GO:0030213,GO:0030213,GO:0030213,GO:0030213,GO:0030213,GO:0030335,GO:0031410,GO:0035810,GO:0036120,GO:0036302,GO:0042802,GO:0044849,GO:0044853,GO:0045226,GO:0045226,GO:0050501,GO:0050501,GO:0050501,GO:0050501,GO:0051549,GO:0060349,GO:0070295,GO:0071347,GO:0071356,GO:0071498,GO:0085029,GO:0085029,GO:0090500,GO:1900026,GO:1900127,GO:1900625,GO:1901201,GO:1903561

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PRDM14 HAS2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 HAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 HAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 HAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 HAS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 HAS2 21795679 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 HAS2 21795679 trascriptional regulation,stimulation inferred by curator TFlink
YY1 HAS2 21795679 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000029D9F1 HAS2 21282569 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D8730 HAS2 23334589 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00003003B4 HAS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 HAS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 HAS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000544FF1 HAS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 HAS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A281 HAS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 HAS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF HAS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 HAS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A HAS2 22927820 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 HAS2 22927820 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 HAS2 22927820 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 HAS2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004AAAFF HAS2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 HAS2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 HAS2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000075D2F5 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 HAS2 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 HAS2 25416803 26887530 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA2 HAS2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
HAS1 HAS2 24234451 25348397 25795779 colocalization,physical association anti tag coimmunoprecipitation,fluorescent resonance energy transfer,confocal microscopy,proximity ligation assay ComPPI,IntAct
HAS2 HAS3 24234451 25348397 25795779 colocalization,physical association anti tag coimmunoprecipitation,fluorescent resonance energy transfer,physical interaction,confocal microscopy,proximity ligation assay ComPPI,IntAct
HAS2 HAS2 24234451 25795779 colocalization,physical association fluorescent resonance energy transfer,confocal microscopy,proximity ligation assay IntAct
SP1 HAS2 16603733 27898060 stimulant N/A OmniPath
SP3 HAS2 16603733 27898060 stimulant N/A OmniPath
HAS2 HMMR 1376732 27898060 stimulant N/A OmniPath
HAS2 CD44 1694723 27898060 stimulant N/A OmniPath

Visualization










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