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GENE：MAP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MAP2
FullNmae microtubule associated protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6839
EnsembleID ENSG00000078018
Uniprot P11137

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MAP2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MAP2 GO:0000226,GO:0000226,GO:0002162,GO:0005198,GO:0005515,GO:0005516,GO:0005737,GO:0005829,GO:0005874,GO:0005875,GO:0008017,GO:0008017,GO:0016358,GO:0021954,GO:0030425,GO:0030517,GO:0031113,GO:0031115,GO:0031175,GO:0031175,GO:0032839,GO:0032880,GO:0043005,GO:0043005,GO:0043025,GO:0043194,GO:0043198,GO:0043203,GO:0044294,GO:0044307,GO:0048156,GO:0048813,GO:0097441,GO:0150001,GO:0150002,GO:0150014,GO:1901953,GO:1902513,GO:1902737,GO:1903744,GO:1904527,GO:1990635,GO:1990769

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 MAP2 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP MAP2 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR MAP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 MAP2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 MAP2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 MAP2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MAP2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MAP2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATD3B MAP2 19880519 trascriptional regulation,stimulation inferred by curator TFlink
HES1 MAP2 19880519 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 MAP2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000013E79D MAP2 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00004900F1 MAP2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001B968D MAP2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 MAP2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000077AED MAP2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00005DEC41 MAP2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001CF056 MAP2 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA MAP2 22135298 phosphorylation N/A PhosphoSite
FYN MAP2 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
DLG4 MAP2 25361965 interaction type N/A PTMCode2
MAP2 DLG4 25361965 interaction type N/A PTMCode2
MAP2 FYN 25361965 interaction type N/A PTMCode2
MAP2 PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 MAP2 25361965 interaction type N/A PTMCode2
APOE MAP2 25361965 interaction type N/A PTMCode2
MAP2 APOE 25361965 interaction type N/A PTMCode2
SRC MAP2 25361965 interaction type N/A PTMCode2
MAP2 SRC 25361965 interaction type N/A PTMCode2
GRB2 MAP2 25361965 interaction type N/A PTMCode2
MAP2 GRB2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PRKAR2B MAP2 25348397 N/A physical interaction ComPPI
ACTB MAP2 25348397 N/A physical interaction,in vitro ComPPI
JUNB MAP2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
SRC MAP2 25348397 N/A physical interaction ComPPI
GRB2 MAP2 15536091 24234451 25348397 association,physical association coimmunoprecipitation,far western blotting,pull down,physical interaction,enzyme linked immunosorbent assay,in vitro,in vivo ComPPI,IntAct
DHX9 MAP2 25348397 N/A physical interaction ComPPI
PRKACA MAP2 25348397 N/A in vitro,in vivo ComPPI
ACTN1 MAP2 25348397 N/A physical interaction ComPPI
NTRK1 MAP2 25348397 N/A physical interaction ComPPI
YBX1 MAP2 25348397 N/A physical interaction ComPPI
HAX1 MAP2 25348397 N/A physical interaction ComPPI
APOE MAP2 25348397 27898060 8624078 N/A in vitro ComPPI,OmniPath
MAP2 PAFAH1B1 25348397 N/A in vitro ComPPI
MAP2 FYN 15536091 24234451 25348397 phosphorylation reaction experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,IntAct
MAP2 PRKAR2A 2147685 25348397 2561973 2701845 27898060 N/A biophysical,physical interaction,in vivo ComPPI,OmniPath
MAP2 MYO7A 25348397 N/A physical interaction,in vivo ComPPI
MAP2 PLEC 25348397 N/A physical interaction,in vitro ComPPI
MAP2 GRIN2D 25348397 N/A in vivo ComPPI
MAP2 MARK1 25348397 N/A in vitro ComPPI
MAP2 MARK4 25348397 N/A physical interaction,in vitro ComPPI
MAP2 CPEB1 25348397 N/A in vitro,in vivo ComPPI
MAP2 TTBK1 25348397 N/A in vitro ComPPI
MAP2 GRIN1 25348397 N/A in vivo ComPPI
MAP2 NEDD4 25348397 N/A physical interaction ComPPI
MAP2 DAG1 25348397 N/A physical interaction ComPPI
MAP2 TUBA1A 11278895 18341635 25348397 2777757 27898060 N/A physical interaction ComPPI,OmniPath
MAP2 MARK3 25348397 N/A physical interaction ComPPI
MAP2 RAE1 25348397 N/A physical interaction ComPPI
MAP2 APP 25348397 N/A physical interaction ComPPI
MAP2 HECW2 25348397 N/A physical interaction ComPPI
MAP2 DYNC1I2 25348397 N/A physical interaction ComPPI
MAP2 HNRNPA0 25348397 N/A physical interaction ComPPI
MAP2 IGF2BP3 25348397 N/A physical interaction ComPPI
MAP2 ABCF1 25348397 N/A physical interaction ComPPI
MAP2 DIMT1 25348397 N/A physical interaction ComPPI
MAP2 EIF3C 25348397 N/A physical interaction ComPPI
MAP2 EIF3K 25348397 N/A physical interaction ComPPI
MAP2 NMT1 25348397 N/A physical interaction ComPPI
MAP2 PA2G4 25348397 N/A physical interaction ComPPI
MAP2 PSMC5 25348397 N/A physical interaction ComPPI
MAP2 PSMD13 25348397 N/A physical interaction ComPPI
MAP2 PSMD8 25348397 N/A physical interaction ComPPI
MAP2 RPL23A 25348397 N/A physical interaction ComPPI
MAP2 ARMC1 25348397 N/A physical interaction ComPPI
MAP2 NUFIP1 25348397 N/A physical interaction ComPPI
MAP2 DGUOK 25348397 N/A physical interaction ComPPI
MAP2 DCTN1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MAP2 MDM2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
MAP2 HNRNPL 25348397 N/A physical interaction ComPPI
MAP2 CBFB 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MAP2 SCHIP1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MAP2 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MAP2 CCP110 18694559 24234451 25348397 physical association two hybrid ComPPI,IntAct
NEDD4L MAP2 25348397 N/A physical interaction ComPPI
NEFL MAP2 25348397 N/A physical interaction ComPPI
CALPB MAP2 19694808 24234451 cleavage reaction protease assay IntAct
HSD17B12 MAP2 24234451 30021884 physical association cross-linking study IntAct
PRKACA MAP2 11029056 12369833 2561875 27898060 8391085 inhibition,stimulant N/A OmniPath
PRKCA MAP2 2561875 27898060 stimulant N/A OmniPath
LYN MAP2 15536091 27898060 stimulant N/A OmniPath
FYN MAP2 11546790 15536091 16145685 27898060 stimulant N/A OmniPath
CAPN1 MAP2 27898060 8391085 inhibition N/A OmniPath
MARK1 MAP2 10542369 27898060 8631898 inhibition N/A OmniPath
CAMK2A MAP2 2561875 27898060 7890745 9341200 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B2865 MAP2 27087310 direct interaction,inhibition N/A NPInter

Visualization










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