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GENE：METAP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol METAP2
FullNmae methionyl aminopeptidase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16672
EnsembleID ENSG00000111142
Uniprot P50579

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
METAP2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
METAP2 GO:0003723,GO:0004177,GO:0004177,GO:0004239,GO:0005515,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0005886,GO:0008235,GO:0008235,GO:0016485,GO:0018206,GO:0031365,GO:0046872,GO:0070006

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 METAP2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 METAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA METAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 METAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 METAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 METAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS METAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PLAGL2 METAP2 17462995 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 METAP2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000031E12 METAP2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000003ABC4 METAP2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000015F70F METAP2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 METAP2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000005481D METAP2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 METAP2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF METAP2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006BE7D METAP2 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
METAP2 S100A4 25361965 interaction type N/A PTMCode2
S100A4 METAP2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CUL5 METAP2 25348397 N/A physical interaction ComPPI
CDC42 METAP2 14525934 25348397 7738010 N/A experimental interaction detection,in vitro ComPPI,HPRD
S100A4 METAP2 11994292 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
CALM1 METAP2 25348397 N/A physical interaction ComPPI
RAC1 METAP2 14525934 25348397 7738010 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK1 METAP2 14525934 15544353 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GRIA3 METAP2 25348397 N/A physical interaction ComPPI
MAPK3 METAP2 14525934 15544353 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
HMGA1 METAP2 25348397 N/A filter binding,physical interaction ComPPI
GAPDH METAP2 25348397 N/A physical interaction ComPPI
NTRK1 METAP2 25348397 N/A physical interaction ComPPI
EIF2AK2 METAP2 11123929 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PVR METAP2 25348397 N/A physical interaction ComPPI
METAP2 EIF2S3 14525934 25348397 27898060 8098621 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
METAP2 APP 25348397 N/A physical interaction ComPPI
METAP2 EEF2K 25348397 N/A physical interaction ComPPI
METAP2 MTOR 25348397 N/A physical interaction ComPPI
METAP2 TKFC 25348397 N/A physical interaction ComPPI
METAP2 GBP1 25348397 N/A physical interaction ComPPI
METAP2 NPEPPS 25348397 N/A physical interaction ComPPI
METAP2 C1QB 25348397 N/A physical interaction ComPPI
METAP2 BSG 25348397 N/A physical interaction ComPPI
METAP2 OTUD6B 25348397 N/A physical interaction ComPPI
METAP2 C1QTNF9 25348397 N/A physical interaction ComPPI
METAP2 GNAS 25348397 N/A physical interaction ComPPI
METAP2 GNAS 25348397 N/A physical interaction ComPPI
METAP2 GNAS 25348397 N/A physical interaction ComPPI
METAP2 PLPPR2 25348397 N/A physical interaction ComPPI
METAP2 ACTL6A 25348397 N/A physical interaction ComPPI
METAP2 TEKT2 25348397 N/A physical interaction ComPPI
METAP2 PLIN5 25348397 N/A physical interaction ComPPI
METAP2 CHD3 25348397 N/A physical interaction ComPPI
METAP2 XPO1 25348397 N/A physical interaction ComPPI
METAP2 YWHAE 25348397 N/A physical interaction ComPPI
METAP2 SUCLA2 25348397 N/A physical interaction ComPPI
METAP2 GPBP1L1 25348397 N/A physical interaction ComPPI
METAP2 TMEM213 25348397 N/A physical interaction ComPPI
METAP2 DDX28 25348397 N/A physical interaction ComPPI
METAP2 CCT7 25348397 N/A physical interaction ComPPI
METAP2 SLC25A25 25348397 N/A physical interaction ComPPI
METAP2 ASB6 25348397 N/A physical interaction ComPPI
METAP2 FCRL2 25348397 N/A physical interaction ComPPI
METAP2 CCT3 25348397 N/A physical interaction ComPPI
METAP2 RGS2 25348397 N/A physical interaction ComPPI
METAP2 TMEM108 25348397 N/A physical interaction ComPPI
METAP2 MRPL35 25348397 N/A physical interaction ComPPI
METAP2 MECP2 25348397 N/A physical interaction ComPPI
METAP2 DLK2 25348397 N/A physical interaction ComPPI
METAP2 NEMP1 25348397 N/A physical interaction ComPPI
METAP2 SUN2 25348397 N/A physical interaction ComPPI
METAP2 TNFRSF19 25348397 N/A physical interaction ComPPI
METAP2 TRIM25 25348397 N/A physical interaction ComPPI
METAP2 PJA1 25348397 N/A physical interaction ComPPI
METAP2 ACADVL 18337751 24234451 25348397 association biochemical ComPPI,IntAct
METAP2 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
METAP2 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
ATP5PO METAP2 24234451 30021884 physical association cross-linking study IntAct

Visualization










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