Gene Information gene info

  1. Home

GENE：MGST1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MGST1
FullNmae microsomal glutathione S-transferase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7061
EnsembleID ENSG00000008394
Uniprot P10620

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MGST1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MGST1 GO:0004364,GO:0004364,GO:0004602,GO:0005515,GO:0005739,GO:0005739,GO:0005741,GO:0005778,GO:0005783,GO:0005789,GO:0005886,GO:0016020,GO:0034635,GO:0035577,GO:0071449,GO:0098869

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MGST1 hsa:4257 path:hsa00480 Glutathione metabolism - Homo sapiens (human)
MGST1 hsa:4257 path:hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human)
MGST1 hsa:4257 path:hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human)
MGST1 hsa:4257 path:hsa00983 Drug metabolism - other enzymes - Homo sapiens (human)
MGST1 hsa:4257 path:hsa01100 Metabolic pathways - Homo sapiens (human)
MGST1 hsa:4257 path:hsa01524 Platinum drug resistance - Homo sapiens (human)
MGST1 hsa:4257 path:hsa05200 Pathways in cancer - Homo sapiens (human)
MGST1 hsa:4257 path:hsa05204 Chemical carcinogenesis - DNA adducts - Homo sapiens (human)
MGST1 hsa:4257 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
MGST1 hsa:4257 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
MGST1 hsa:4257 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
MGST1 hsa:4257 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LTC4S MGST1 23180781 8954909 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
MYC MGST1 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MGST1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MGST1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MGST1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MGST1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MGST1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MGST1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MGST1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000016FF9C MGST1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000013DD8 MGST1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
MGST1 LTC4S 25361965 interaction type N/A PTMCode2
LTC4S MGST1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ERBB2 MGST1 24189400 24234451 25348397 association tandem affinity purification ComPPI,IntAct
NELFB MGST1 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
SIGLEC12 MGST1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EGF MGST1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EGFR MGST1 25348397 N/A physical interaction ComPPI
RAB11A MGST1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRIM25 MGST1 25348397 N/A physical interaction ComPPI
ESRRB MGST1 25348397 N/A physical interaction ComPPI
FZD7 MGST1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C MGST1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MGST1 LTC4S 11034337 14525934 25348397 27898060 7663172 8954909 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
MGST1 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MGST1 COQ9 25348397 N/A physical interaction ComPPI
MGST1 COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
MGST1 MGST1 14525934 14726533 N/A experimental interaction detection HPRD
SP1 MGST1 12818425 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009AECD3 MGST1 27087310 direct interaction,inhibition N/A NPInter

Visualization










  Return