GENE：ONECUT1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ONECUT1 |
| FullNmae | one cut homeobox 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:8138 |
| EnsembleID | ENSG00000169856 |
| Uniprot | Q9UBC0 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ONECUT1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ONECUT1 | GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0001889,GO:0001952,GO:0002064,GO:0003309,GO:0003310,GO:0003311,GO:0003682,GO:0005634,GO:0006006,GO:0006355,GO:0006357,GO:0007179,GO:0007219,GO:0007492,GO:0009653,GO:0016477,GO:0030183,GO:0030335,GO:0030512,GO:0045165,GO:0045944,GO:0048536,GO:0060271,GO:1990837 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ONECUT1 | hsa:3175 | path:hsa04550 | Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human) |
| ONECUT1 | hsa:3175 | path:hsa04950 | Maturity onset diabetes of the young - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NR0B2 | ONECUT1 | 18459945 | interaction type,inhibition | N/A | SignaLink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PRDM14 | ONECUT1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ONECUT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ONECUT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ONECUT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ONECUT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETS1 | ONECUT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ONECUT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | ONECUT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ONECUT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ONECUT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | ONECUT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | ONECUT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NR0B2 | ONECUT1 | 25361965 | interaction type | N/A | PTMCode2 |
| ONECUT1 | NR0B2 | 25361965 | interaction type | N/A | PTMCode2 |
| KAT2B | ONECUT1 | 25361965 | interaction type | N/A | PTMCode2 |
| ONECUT1 | KAT2B | 25361965 | interaction type | N/A | PTMCode2 |
| ONECUT1 | FOXA2 | 25361965 | interaction type | N/A | PTMCode2 |
| FOXA2 | ONECUT1 | 25361965 | interaction type | N/A | PTMCode2 |
| NR3C1 | ONECUT1 | 25361965 | interaction type | N/A | PTMCode2 |
| ONECUT1 | NR3C1 | 25361965 | interaction type | N/A | PTMCode2 |
| FOXA1 | ONECUT1 | 25361965 | interaction type | N/A | PTMCode2 |
| ONECUT1 | FOXA1 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CREBBP | ONECUT1 | 10811635 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| KAT2B | ONECUT1 | 10811635 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| SERPINB13 | ONECUT1 | 25348397 | N/A | physical interaction | ComPPI |
| NR0B2 | ONECUT1 | 18459945 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| NR3C1 | ONECUT1 | 10430878 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
| FOXA1 | ONECUT1 | 25348397 | N/A | physical interaction | ComPPI |
| ONECUT1 | FOXA2 | 12509444 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |