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GENE：OTUD4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol OTUD4
FullNmae OTU deubiquitinase 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24949
EnsembleID ENSG00000164164
Uniprot Q01804

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
OTUD4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
OTUD4 GO:0003723,GO:0004843,GO:0004843,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0016579,GO:0034122,GO:0034122,GO:0045087,GO:0060090,GO:0061578,GO:0061578,GO:0070536,GO:0071108,GO:1901537,GO:1903093,GO:1903093,GO:2000660,GO:2000660

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PRR5 OTUD4 17461779 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR OTUD4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 OTUD4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 OTUD4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 OTUD4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 OTUD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA OTUD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF OTUD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 OTUD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 OTUD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A OTUD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF OTUD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 OTUD4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C0FCB OTUD4 20371350 22012620 23446348 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00002152A8 OTUD4 20371350 22473208 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000345DEB OTUD4 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000DDD35 OTUD4 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000035CC3E OTUD4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003A5E54 OTUD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA OTUD4 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 OTUD4 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 OTUD4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 OTUD4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 OTUD4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 OTUD4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 OTUD4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004ACAAA OTUD4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 OTUD4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 OTUD4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F OTUD4 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 OTUD4 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000098B3B OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000521626 OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003BBF48 OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 OTUD4 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B OTUD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC OTUD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A3D OTUD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 OTUD4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 OTUD4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F OTUD4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 OTUD4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 OTUD4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD1DE OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000081D1E OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000001EB3 OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001310DE OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001DC1D3 OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C403E OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000023133F OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000004BACE OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000077DDE OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000250A40 OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000027464B OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000EC1BE OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001012BC OTUD4 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FXR2 OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STAT1 OTUD4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRT33B OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRT31 OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOSC8 OTUD4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CDK5RAP3 OTUD4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PARP11 OTUD4 25348397 N/A physical interaction ComPPI
REL OTUD4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
USP7 OTUD4 25348397 N/A physical interaction ComPPI
FLNC OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBC OTUD4 25348397 N/A physical interaction ComPPI
CLEC3B OTUD4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
VTN OTUD4 25348397 N/A physical interaction ComPPI
ILK OTUD4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FMNL1 OTUD4 25348397 N/A physical interaction ComPPI
MOG OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYC OTUD4 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
GRK5 OTUD4 25348397 N/A physical interaction ComPPI
XPO1 OTUD4 25348397 N/A physical interaction ComPPI
TRAF1 OTUD4 25348397 N/A physical interaction ComPPI
BRF2 OTUD4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBA1A OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYCBP OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H3C1 OTUD4 25348397 N/A physical interaction ComPPI
GPHN OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DUSP10 OTUD4 25348397 N/A physical interaction ComPPI
GAR1 OTUD4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRPF4 OTUD4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNAJB1 OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBFOX2 OTUD4 25348397 N/A physical interaction ComPPI
OAT OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NMD3 OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATG12 OTUD4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
KRT8 OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARHGAP8 OTUD4 25348397 N/A anti tag coimmunoprecipitation ComPPI
DSG1 OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RUNX1T1 OTUD4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CYLD OTUD4 25348397 N/A physical interaction ComPPI
ZNF655 OTUD4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PCGF1 OTUD4 24234451 25348397 27505670 association tandem affinity purification ComPPI,IntAct
FBL OTUD4 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSF2 OTUD4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRT85 OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TCF4 OTUD4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
IQCN OTUD4 25348397 N/A physical interaction ComPPI
TMBIM4 OTUD4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
OTUD4 GALK1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OTUD4 GLA 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OTUD4 KRT36 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OTUD4 NPEPPS 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OTUD4 RPTN 25348397 N/A physical interaction ComPPI
OTUD4 AGO3 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OTUD4 WBP2NL 25348397 N/A physical interaction ComPPI
OTUD4 LHX6 25348397 N/A physical interaction ComPPI
OTUD4 NAF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
OTUD4 ALKBH3 25348397 N/A physical interaction ComPPI
OTUD4 ALKBH2 25348397 N/A physical interaction ComPPI
OTUD4 USP9X 25348397 N/A physical interaction ComPPI
OTUD4 RC3H1 25348397 N/A physical interaction ComPPI
OTUD4 FAN1 25348397 N/A physical interaction ComPPI
OTUD4 TPTE2 25348397 N/A physical interaction ComPPI
OTUD4 HTRA4 25348397 N/A physical interaction ComPPI
OTUD4 ODAPH 25348397 N/A physical interaction ComPPI
OTUD4 TSPYL6 25348397 N/A physical interaction ComPPI
OTUD4 PRR5 25348397 N/A anti tag coimmunoprecipitation ComPPI
OTUD4 HRNR 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
OTUD4 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
BAG5 OTUD4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

Visualization










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