Gene Information gene info

  1. Home

GENE：RALA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RALA
FullNmae RAS like proto-oncogene A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9839
EnsembleID ENSG00000006451
Uniprot P11233

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RALA immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RALA GO:0001843,GO:0003924,GO:0003924,GO:0003925,GO:0005515,GO:0005525,GO:0005525,GO:0005739,GO:0005886,GO:0005886,GO:0005925,GO:0005925,GO:0006887,GO:0006935,GO:0007049,GO:0007165,GO:0007265,GO:0007265,GO:0009986,GO:0017022,GO:0017157,GO:0017157,GO:0019003,GO:0019003,GO:0030139,GO:0030659,GO:0031623,GO:0031625,GO:0031755,GO:0032154,GO:0032956,GO:0045742,GO:0051117,GO:0051301,GO:0051491,GO:0051665,GO:0070062,GO:0072655,GO:0090141,GO:0090543,GO:0097060,GO:0098685,GO:0099149

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RALA hsa:5898 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
RALA hsa:5898 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
RALA hsa:5898 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
RALA hsa:5898 path:hsa05132 Salmonella infection - Homo sapiens (human)
RALA hsa:5898 path:hsa05200 Pathways in cancer - Homo sapiens (human)
RALA hsa:5898 path:hsa05210 Colorectal cancer - Homo sapiens (human)
RALA hsa:5898 path:hsa05212 Pancreatic cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RALA EXOC2 17018283 23180781 physical association pull down InnateDB
RALA RGL2 23180781 8939933 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR RALA 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RALA 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 RALA 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 RALA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000021D7C8 RALA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000821E0 RALA 22815788 24063364 25416803 26175215 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
AURKA RALA 22135298 phosphorylation N/A PhosphoSite
REPS1 RALA 25361965 interaction type N/A PTMCode2
RALA REPS1 25361965 interaction type N/A PTMCode2
EXOC2 RALA 25361965 interaction type N/A PTMCode2
RALA EXOC2 25361965 interaction type N/A PTMCode2
RALBP1 RALA 25361965 interaction type N/A PTMCode2
RALA RALBP1 25361965 interaction type N/A PTMCode2
RALA RALGPS1 25361965 interaction type N/A PTMCode2
RALGPS1 RALA 25361965 interaction type N/A PTMCode2
RALA ARF1 25361965 interaction type N/A PTMCode2
ARF1 RALA 25361965 interaction type N/A PTMCode2
RALA EXOC6B 25361965 interaction type N/A PTMCode2
EXOC6B RALA 25361965 interaction type N/A PTMCode2
RALA RGL4 25361965 interaction type N/A PTMCode2
RGL4 RALA 25361965 interaction type N/A PTMCode2
RALA ARF6 25361965 interaction type N/A PTMCode2
ARF6 RALA 25361965 interaction type N/A PTMCode2
RALA HRAS 25361965 interaction type N/A PTMCode2
HRAS RALA 25361965 interaction type N/A PTMCode2
RALA PPP2R1B 25361965 interaction type N/A PTMCode2
PPP2R1B RALA 25361965 interaction type N/A PTMCode2
RALA PLD1 25361965 interaction type N/A PTMCode2
PLD1 RALA 25361965 interaction type N/A PTMCode2
RALA CNKSR2 25361965 interaction type N/A PTMCode2
CNKSR2 RALA 25361965 interaction type N/A PTMCode2
RALA RGL2 25361965 interaction type N/A PTMCode2
RGL2 RALA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EXOC5 RALA 11406615 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RALBP1 RALA 14525934 24234451 25241761 25348397 28851898 7673236 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,proximity ligation assay,two hybrid ComPPI,HPRD,IntAct
VPS4B RALA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCND1 RALA 21242975 24234451 25348397 27898060 colocalization confocal microscopy ComPPI,IntAct,OmniPath
LSM2 RALA 25348397 N/A physical interaction ComPPI
MCM5 RALA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CALM1 RALA 25348397 N/A pull down,physical interaction ComPPI
SMAD4 RALA 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RASSF5 RALA 14525934 25348397 9488663 N/A two hybrid,two hybrid ComPPI,HPRD
EXOC8 RALA 11406615 14525934 14525976 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
HRAS RALA 19222999 24234451 25348397 N/A pull down ComPPI,IntAct
NONO RALA 25348397 N/A physical interaction ComPPI
FLNA RALA 10051605 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NTRK1 RALA 25348397 N/A physical interaction ComPPI
LAMTOR3 RALA 25348397 N/A physical interaction ComPPI
AKR7A2 RALA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RALA CNKSR2 14525934 14597674 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RALA EXOC1 11406615 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RALA REPS1 14525934 25348397 7623849 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
RALA EXOC3 11406615 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RALA RAB8B 10889189 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
RALA RALGPS1 10889189 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RALA EXOC2 11744922 12624092 12839989 14525934 14525976 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RALA EXOC4 11406615 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RALA YBX3 14525934 15592429 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
RALA PLCD1 14525934 15817490 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
RALA PPP2R1B 14525934 17540176 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
RALA ARF1 12509462 14525934 25348397 27898060 9688545 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
RALA TSC2 25348397 N/A physical interaction ComPPI
RALA PLD1 14525934 25348397 9207251 N/A experimental interaction detection,physical interaction ComPPI,HPRD
RALA RGL2 25348397 N/A physical interaction ComPPI
RALA ARF6 25348397 N/A physical interaction ComPPI
RALA PPP2CA 25348397 N/A physical interaction ComPPI
RALA ELAVL1 25348397 N/A physical interaction ComPPI
RALA MYO1G 25348397 N/A physical interaction ComPPI
RALA MPV17 25348397 N/A physical interaction ComPPI
RALA MARCKSL1 25348397 N/A physical interaction ComPPI
RALA MSLN 25348397 N/A physical interaction ComPPI
RALA NDUFS6 25348397 N/A physical interaction ComPPI
RALA MYH10 25348397 N/A physical interaction ComPPI
RALA MYH9 25348397 N/A physical interaction ComPPI
RALA ILF3 25348397 N/A physical interaction ComPPI
RALA RAB34 25348397 N/A physical interaction ComPPI
RALA RAB34 25348397 N/A physical interaction ComPPI
RALA PIH1D2 25348397 N/A physical interaction ComPPI
RALA USP33 25348397 N/A physical interaction ComPPI
RALA CUL7 25348397 N/A physical interaction ComPPI
RALA CCDC8 25348397 N/A physical interaction ComPPI
RALA ABCE1 25348397 N/A physical interaction ComPPI
RALA SLC25A41 25348397 N/A physical interaction ComPPI
RALA HSPB1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
RALA GLS2 25348397 N/A physical interaction ComPPI
RALA ATP5PF 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RALA FLNB 25348397 N/A physical interaction ComPPI
RALA GPT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RALA MYO1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RALA ATP6AP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RALA LIMA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RALA ZNHIT3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RALA NOS1AP 25348397 N/A physical interaction ComPPI
RALA INTS7 25348397 N/A physical interaction ComPPI
RALA RHOF 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RALA CEP55 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RALA FBH1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RALA KIAA2013 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RALA TRIM25 25348397 N/A physical interaction ComPPI
RALA HNRNPL 25348397 N/A physical interaction ComPPI
RALA CTCF 24234451 24725430 25348397 physical association two hybrid ComPPI,IntAct
AP4M1 RALA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FAM3C RALA 25348397 N/A physical interaction ComPPI
HSCB RALA 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
RALA WNT5 25348397 N/A two hybrid,physical interaction,physical interaction ComPPI
RGL4 RALA 12874025 14525934 N/A experimental interaction detection HPRD
EXOC7 RALA 11406615 14525934 N/A experimental interaction detection HPRD
RALA CALM2 12034722 14525934 24234451 9188503 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,two hybrid HPRD,IntAct
EXOC6B RALA 11406615 14525934 N/A experimental interaction detection HPRD
RALA RBMXL2 24234451 30021884 physical association cross-linking study IntAct
RALA DDN 24234451 30021884 physical association cross-linking study IntAct
DNAJB11 RALA 24234451 30021884 physical association cross-linking study IntAct
ZBTB10 RALA 24234451 30021884 physical association cross-linking study IntAct
SMC3 RALA 24234451 30021884 physical association cross-linking study IntAct
AURKA RALA 17540176 19901077 21822277 27898060 N/A N/A OmniPath
PPP2R1B RALA 17540176 27898060 N/A N/A OmniPath
RALA RALBP1 10393179 14525976 25241761 27898060 7623849 7673236 9422736 stimulant N/A OmniPath
RALGDS RALA 20478380 27898060 8094051 stimulant N/A OmniPath
PPP2CB RALA 17540176 27898060 inhibition N/A OmniPath

Visualization










  Return