Gene Information gene info

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GENE：SLK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLK
FullNmae STE20 like kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11088
EnsembleID ENSG00000065613
Uniprot Q9H2G2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLK immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SLK autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SLK apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SLK GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005737,GO:0005737,GO:0005829,GO:0006468,GO:0006915,GO:0030334,GO:0030334,GO:0030334,GO:0031122,GO:0031252,GO:0042802,GO:0042803,GO:0042981,GO:0042981,GO:0045296,GO:0046777,GO:0048471,GO:0051893,GO:0070062,GO:0106310

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SLK hsa:9748 path:hsa04114 Oocyte meiosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 SLK 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SLK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SLK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SLK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SLK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SLK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SLK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SLK 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D SLK 18591254 20371350 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 SLK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE SLK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 SLK 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F SLK 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 SLK 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 SLK 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 SLK 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 SLK 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA SLK 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CASP3 SLK 25361965 interaction type N/A PTMCode2
SLK CASP3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPP1R2B SLK 25348397 N/A physical interaction ComPPI
KEAP1 SLK 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBM8A SLK 25348397 N/A physical interaction ComPPI
ARHGEF1 SLK 25348397 N/A physical interaction ComPPI
CASP3 SLK 10611247 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
NONO SLK 25348397 N/A physical interaction ComPPI
YWHAB SLK 25348397 N/A physical interaction ComPPI
YWHAZ SLK 25348397 N/A physical interaction ComPPI
HGS SLK 25348397 N/A physical interaction ComPPI
NTRK1 SLK 25348397 N/A physical interaction ComPPI
CDH1 SLK 25348397 N/A physical interaction ComPPI
CLSTN1 SLK 12421765 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PDZK1 SLK 25348397 N/A physical interaction ComPPI
SFN SLK 25348397 N/A physical interaction ComPPI
GTF2E2 SLK 25348397 N/A physical interaction ComPPI
GABARAP SLK 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
FGB SLK 25348397 N/A physical interaction ComPPI
SLK PDZK1P1 25348397 N/A physical interaction ComPPI
SLK RABL2A 25348397 N/A physical interaction ComPPI
SLK HGH1 25348397 N/A physical interaction ComPPI
SLK TTC4 25348397 N/A physical interaction ComPPI
SLK MRPL43 25348397 N/A physical interaction ComPPI
SLK NSFL1C 25348397 N/A physical interaction ComPPI
SLK PPP1R2 25348397 N/A physical interaction ComPPI
SLK MAP4 25348397 N/A physical interaction ComPPI
SLK PITHD1 25348397 N/A physical interaction ComPPI
SLK MED4 25348397 N/A physical interaction ComPPI
SLK IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SNRNP27 SLK 25348397 N/A physical interaction ComPPI
SLK SLK 18239682 24234451 N/A cosedimentation in solution,cross-linking study,x-ray crystallography IntAct
HSPA9 SLK 24234451 30021884 physical association cross-linking study IntAct
AIFM1 SLK 24234451 30021884 physical association cross-linking study IntAct
SLK MAP3K5 16316999 27898060 stimulant N/A OmniPath
CSNK2A1 SLK 16837460 27898060 inhibition N/A OmniPath

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