Gene Information gene info

GENE:TGFBRAP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TGFBRAP1
FullNmae transforming growth factor beta receptor associated protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16836
EnsembleID ENSG00000135966
Uniprot Q8WUH2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TGFBRAP1 lysosomal_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TGFBRAP1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TGFBRAP1 GO:0005160,GO:0005515,GO:0005737,GO:0005769,GO:0006355,GO:0006886,GO:0006914,GO:0007165,GO:0007179,GO:0008333,GO:0016020,GO:0016020,GO:0033263,GO:0034058,GO:0034058,GO:0034058,GO:0035542,GO:0043231,GO:0046332

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TGFBRAP1 hsa:9392 path:hsa04148 Efferocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TGFBRAP1 TGFBR1 23180781 9545258 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
TGFBRAP1 BMPR1A 20005715 interaction type N/A PSP
TGFBRAP1 ACVR1B 20005715 interaction type N/A PSP
TGFBRAP1 TGFBR1 20005715 interaction type N/A PSP
TGFBRAP1 ACVRL1 20005715 interaction type N/A PSP
TGFBRAP1 TGFBR2 20005715 interaction type N/A PSP
TGFBRAP1 ACVR2B 20005715 interaction type N/A PSP
TGFBRAP1 TGFBR1 11278302 18988627 20005715 9545258 N/A N/A SignaLink
TGFBRAP1 TGFBR2 11278302 18988627 20005715 N/A N/A SignaLink
TGFBRAP1 ACVR1B 11278302 18988627 20005715 20005715 N/A N/A SignaLink
TGFBRAP1 ACVR2B 11278302 18988627 20005715 20005715 N/A N/A SignaLink
TGFBRAP1 ACVRL1 11278302 18988627 20005715 20005715 N/A N/A SignaLink
TGFBRAP1 BMPR1A 11278302 18988627 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR TGFBRAP1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TGFBRAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TGFBRAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TGFBRAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TGFBRAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TGFBRAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TGFBRAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 TGFBRAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TGFBRAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TGFBRAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TGFBRAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYB TGFBRAP1 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYC TGFBRAP1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003380CC TGFBRAP1 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00004B83FE TGFBRAP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003003B4 TGFBRAP1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA TGFBRAP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 TGFBRAP1 25416803 26682928 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
VPS11 TGFBRAP1 24234451 25266290 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMAD4 TGFBRAP1 11278302 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
APPL1 TGFBRAP1 24234451 25266290 25348397 colocalization confocal microscopy ComPPI,IntAct
TGFBR2 TGFBRAP1 11278302 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SMAD2 TGFBRAP1 11278302 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
NRBF2 TGFBRAP1 25348397 N/A physical interaction ComPPI
HNRNPL TGFBRAP1 25348397 N/A physical interaction ComPPI
RAB5A TGFBRAP1 24234451 25266290 25348397 colocalization confocal microscopy ComPPI,IntAct
EEA1 TGFBRAP1 24234451 25266290 25348397 colocalization confocal microscopy ComPPI,IntAct
ALOX5 TGFBRAP1 10051563 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ACVR1B TGFBRAP1 11278302 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ACVRL1 TGFBRAP1 11278302 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGFBRAP1 BMPR1A 11278302 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGFBRAP1 ACVR2B 11278302 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TGFBRAP1 UVRAG 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TGFBRAP1 VPS41 25348397 N/A physical interaction ComPPI
TGFBRAP1 ACVR1 25348397 N/A physical interaction ComPPI
TGFBRAP1 TGFBR1 11278302 14525934 25348397 9545258 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
TGFBRAP1 VPS18 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TGFBRAP1 VPS16 24234451 25266290 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TGFBRAP1 VPS8 24234451 25266290 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TGFBRAP1 VPS33A 25348397 N/A physical interaction ComPPI
TGFBRAP1 ISOC2 25348397 N/A physical interaction ComPPI
TGFBRAP1 TMEM266 25348397 N/A physical interaction ComPPI
TGFBRAP1 ARFGAP1 25348397 N/A physical interaction ComPPI
TGFBRAP1 BMT2 25348397 N/A physical interaction ComPPI
TGFBRAP1 CROCC 25348397 N/A physical interaction ComPPI
TGFBRAP1 TRIM25 25348397 N/A physical interaction ComPPI
TGFBRAP1 RAB5C 24234451 25266290 25348397 colocalization,physical association pull down,confocal microscopy ComPPI,IntAct
TGFBR1 TGFBRAP1 11278302 27898060 9545258 N/A N/A OmniPath

Visualization