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GENE：TMC5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TMC5
FullNmae transmembrane channel like 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:22999
EnsembleID ENSG00000103534
Uniprot Q6UXY8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TMC5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TMC5 GO:0005886,GO:0008381,GO:0034220,GO:0070062

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 TMC5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 TMC5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TMC5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 TMC5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 TMC5 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TMC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TMC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TMC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TMC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TMC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TMC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TMC5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C02E4 TMC5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 TMC5 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD TMC5 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F TMC5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000086A4D TMC5 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E TMC5 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000A9FB9 TMC5 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 TMC5 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TRIM25 TMC5 25348397 N/A physical interaction ComPPI
NUMBL TMC5 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct

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