Gene Information gene info

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GENE：DAD1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DAD1
FullNmae defender against cell death 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2664
EnsembleID ENSG00000129562
Uniprot P61803

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DAD1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DAD1 GO:0001824,GO:0005789,GO:0005789,GO:0006486,GO:0006487,GO:0006487,GO:0006915,GO:0008047,GO:0008250,GO:0008250,GO:0008250,GO:0008250,GO:0016020,GO:0018279,GO:0031647,GO:0043066

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DAD1 hsa:1603 path:hsa00510 N-Glycan biosynthesis - Homo sapiens (human)
DAD1 hsa:1603 path:hsa00513 Various types of N-glycan biosynthesis - Homo sapiens (human)
DAD1 hsa:1603 path:hsa01100 Metabolic pathways - Homo sapiens (human)
DAD1 hsa:1603 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EED DAD1 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 DAD1 23180781 23798571 physical association affinity chromatography technology InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 DAD1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 DAD1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 DAD1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 DAD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DAD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DAD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DAD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 DAD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 DAD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DAD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 DAD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 DAD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000013E79D DAD1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 DAD1 21572407 22473208 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000020579D DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000031602A DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000251D0B DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C11BC DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002C0FCB DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000315338 DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000508C13 DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041E949 DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000027080C DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000346991 DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000070CD2 DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000037D7E5 DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003883FE DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000065FDF DAD1 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000096022 DAD1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003B6B84 DAD1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003538C1 DAD1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000355E82 DAD1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001012BC DAD1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DAD1 STT3B 25361965 interaction type N/A PTMCode2
STT3B DAD1 25361965 interaction type N/A PTMCode2
DAD1 RPN1 25361965 interaction type N/A PTMCode2
RPN1 DAD1 25361965 interaction type N/A PTMCode2
DAD1 MAGT1 25361965 interaction type N/A PTMCode2
MAGT1 DAD1 25361965 interaction type N/A PTMCode2
DAD1 DDOST 25361965 interaction type N/A PTMCode2
DDOST DAD1 25361965 interaction type N/A PTMCode2
DAD1 STT3A 25361965 interaction type N/A PTMCode2
STT3A DAD1 25361965 interaction type N/A PTMCode2
TUSC3 DAD1 25361965 interaction type N/A PTMCode2
DAD1 TUSC3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ISG15 DAD1 24234451 25348397 26259872 association pull down ComPPI,IntAct
GLP1R DAD1 25348397 N/A physical interaction ComPPI
MCL1 DAD1 10965038 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
EFNB2 DAD1 25348397 N/A physical interaction ComPPI
CDK2 DAD1 25348397 N/A physical interaction ComPPI
ADRB2 DAD1 25348397 N/A physical interaction ComPPI
EED DAD1 25348397 N/A physical interaction ComPPI
VIPR2 DAD1 25348397 N/A physical interaction ComPPI
SGCA DAD1 25348397 N/A physical interaction ComPPI
FSHR DAD1 25348397 N/A physical interaction ComPPI
DAD1 HSD11B1 25348397 N/A physical interaction ComPPI
DAD1 F3 25348397 N/A physical interaction ComPPI
DAD1 LRRTM2 25348397 N/A physical interaction ComPPI
DAD1 CLEC5A 25348397 N/A physical interaction ComPPI
DAD1 TCTN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DAD1 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DAD1 TMEM258 25348397 N/A physical interaction ComPPI
DAD1 PDCD1 25348397 N/A physical interaction ComPPI
DAD1 RPN2 25348397 N/A physical interaction ComPPI
DAD1 SLC5A8 25348397 N/A physical interaction ComPPI
DAD1 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DAD1 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DAD1 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSCB DAD1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
BCAS2 DAD1 11553702 11756468 12408861 12925767 15640796 20730753 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009AE975 DAD1 27087310 direct interaction,inhibition N/A NPInter

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