Gene Information gene info

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GENE：GFI1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GFI1
FullNmae growth factor independent 1 transcriptional repressor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4237
EnsembleID ENSG00000162676
Uniprot Q99684

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GFI1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GFI1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GFI1 GO:0000083,GO:0000122,GO:0000976,GO:0000978,GO:0001227,GO:0003700,GO:0005515,GO:0005634,GO:0006357,GO:0010956,GO:0010957,GO:0010977,GO:0016032,GO:0016363,GO:0016604,GO:0017053,GO:0032088,GO:0034121,GO:0045892,GO:0046872,GO:0070105,GO:0071222,GO:1990837

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RELA GFI1 20547752 23180781 physical association anti tag coimmunoprecipitation InnateDB
UBE2I GFI1 19506020 23180781 physical association two hybrid InnateDB
PIAS4 GFI1 19506020 23180781 physical association two hybrid InnateDB
IPO8 GFI1 19506020 23180781 physical association two hybrid InnateDB
PCNA GFI1 19506020 23180781 physical association two hybrid InnateDB
PRDM5 GFI1 19506020 23180781 physical association two hybrid InnateDB
ZSCAN22 GFI1 19506020 23180781 physical association two hybrid InnateDB
ZXDC GFI1 19506020 23180781 physical association two hybrid InnateDB
SNRPD1 GFI1 19506020 23180781 physical association two hybrid InnateDB
HMGB2 GFI1 19506020 23180781 physical association two hybrid InnateDB
PCBP1 GFI1 19506020 23180781 physical association two hybrid InnateDB
CD81 GFI1 19506020 23180781 physical association two hybrid InnateDB
EPB42 GFI1 19506020 23180781 physical association two hybrid InnateDB
SYTL1 GFI1 19506020 23180781 physical association two hybrid InnateDB
TIMM50 GFI1 19506020 23180781 physical association two hybrid InnateDB
SDHB GFI1 19506020 23180781 physical association two hybrid InnateDB
TTN GFI1 19506020 23180781 physical association two hybrid InnateDB
FBN2 GFI1 19506020 23180781 physical association two hybrid InnateDB
RPS20 GFI1 19506020 23180781 physical association two hybrid InnateDB
EIF3D GFI1 19506020 23180781 physical association two hybrid InnateDB
GFI1 N4BP2L2 19506020 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
GFI1 ELANE 19506020 23180781 physical association anti tag coimmunoprecipitation InnateDB
ETS2 GFI1 16287849 23180781 physical association anti tag coimmunoprecipitation InnateDB
CDKN1A GFI1 16287849 23180781 physical association anti tag coimmunoprecipitation InnateDB
E2F5 GFI1 16287849 23180781 physical association anti tag coimmunoprecipitation InnateDB
MYC GFI1 16287849 23180781 physical association anti tag coimmunoprecipitation InnateDB
EHMT2 GFI1 16287849 23180781 physical association anti tag coimmunoprecipitation InnateDB
HDAC1 GFI1 16287849 23180781 physical association anti tag coimmunoprecipitation InnateDB
GUCY1B1 GFI1 14504408 23180781 physical association affinity chromatography technology InnateDB
GFI1 MYB 23180781 24121275 physical association anti tag coimmunoprecipitation InnateDB
TBX21 GFI1 23180781 23232398 physical association anti tag coimmunoprecipitation InnateDB
GATA3 GFI1 23180781 23232398 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GFI1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 GFI1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 GFI1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 GFI1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 GFI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GFI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GFI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GFI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GFI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GFI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 GFI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 GFI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR GFI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZBTB16 GFI1 19723763 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000052E1A6 GFI1 24334453 25416803 mrna cleavage,inhibition chromatin immunoprecipitation assay TarBase
URS00001E0AEA GFI1 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GFI1 ARIH2 25361965 interaction type N/A PTMCode2
ARIH2 GFI1 25361965 interaction type N/A PTMCode2
GFI1 ZBTB17 25361965 interaction type N/A PTMCode2
ZBTB17 GFI1 25361965 interaction type N/A PTMCode2
GFI1 EHMT2 25361965 interaction type N/A PTMCode2
EHMT2 GFI1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I GFI1 17636019 24234451 25348397 physical association two hybrid ComPPI,IntAct
EHMT2 GFI1 16287849 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PICK1 GFI1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SPI1 GFI1 17197705 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
CHAF1A GFI1 21570500 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct,OmniPath
RELA GFI1 20547752 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC2 GFI1 25348397 N/A physical interaction ComPPI
ZBTB17 GFI1 19164764 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PIAS4 GFI1 17636019 24234451 25348397 physical association two hybrid ComPPI,IntAct
GFI1 PIAS3 11060035 14525934 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
GFI1 RUNX1T1 12874834 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
GFI1 HDAC1 16287849 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GFI1 PRDM5 17636019 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
GFI1 RCOR1 25348397 N/A physical interaction ComPPI
GFI1 KDM1A 25348397 N/A physical interaction ComPPI
GFI1 U2AF1L4 16819553 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation ComPPI,IntAct,OmniPath
GFI1 TP53 23410974 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
ARIH2 GFI1 25348397 N/A physical interaction ComPPI
POU4F3 GFI1 15254021 27898060 stimulant N/A OmniPath
ZBTB16 GFI1 19723763 27898060 inhibition N/A OmniPath
GFI1 RELA 20547752 27898060 N/A N/A OmniPath
PROX1 GFI1 18652815 27898060 inhibition N/A OmniPath
GFI1 BAX 12874834 27898060 inhibition N/A OmniPath
GFI1 PIAS4 17636019 19506020 27898060 N/A N/A OmniPath
GFI1 CDKN1C 18652815 27898060 stimulant N/A OmniPath
ETS1 GFI1 17213822 27898060 inhibition N/A OmniPath
GFI1 ETS1 17213822 27898060 inhibition N/A OmniPath

Visualization










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