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GENE：SKA2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SKA2
FullNmae spindle and kinetochore associated complex subunit 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28006
EnsembleID ENSG00000182628
Uniprot Q8WVK7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SKA2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SKA2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SKA2 GO:0000278,GO:0000278,GO:0000776,GO:0000940,GO:0000940,GO:0005515,GO:0005829,GO:0005876,GO:0005876,GO:0007059,GO:0007059,GO:0008017,GO:0008017,GO:0031110,GO:0051301

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 SKA2 11799066 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 SKA2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 SKA2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 SKA2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA SKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR SKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 SKA2 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS000000B1C9 SKA2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000939AF SKA2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 SKA2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE SKA2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000572E11 SKA2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000028D811 SKA2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B SKA2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A SKA2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 SKA2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A SKA2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000058276F SKA2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 SKA2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE SKA2 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 SKA2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
DCTN1 SKA2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IFT57 SKA2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HAUS1 SKA2 25348397 N/A physical interaction ComPPI
DSN1 SKA2 25348397 N/A physical interaction ComPPI
PRKD3 SKA2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EZR SKA2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RALYL SKA2 25348397 N/A physical interaction ComPPI
SKA1 SKA2 14525934 17093495 19360002 24234451 25348397 26496610 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,molecular sieving,pull down,physical interaction,imaging technique,in vivo,two hybrid ComPPI,HPRD,IntAct
SKA2 PPP2R2B 19156129 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B79A6 SKA2 27087310 direct interaction,inhibition N/A NPInter

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