Gene Information gene info

GENE:TAP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TAP2
FullNmae transporter 2, ATP binding cassette subfamily B member
LocusType gene with protein product
Status Approved
HGNC_id HGNC:44
EnsembleID ENSG00000204267
Uniprot Q03519

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TAP2 immunogenic 36579538 Through literature reviews, a total of 108 ICD-related genes were identified (Supplement Table S1). retulator signature

Go Annotation:

GeneSymbol Go id
TAP2 GO:0001913,GO:0001916,GO:0002237,GO:0002481,GO:0002485,GO:0002489,GO:0005515,GO:0005524,GO:0005524,GO:0005783,GO:0005789,GO:0005789,GO:0015031,GO:0015433,GO:0015433,GO:0015440,GO:0016020,GO:0016020,GO:0016607,GO:0016887,GO:0019885,GO:0019885,GO:0023029,GO:0030670,GO:0033116,GO:0042605,GO:0042824,GO:0042825,GO:0046872,GO:0046967,GO:0046968,GO:0046968,GO:0046978,GO:0046980,GO:0055085,GO:1904680

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TAP2 hsa:6891 path:hsa02010 ABC transporters - Homo sapiens (human)
TAP2 hsa:6891 path:hsa04145 Phagosome - Homo sapiens (human)
TAP2 hsa:6891 path:hsa04612 Antigen processing and presentation - Homo sapiens (human)
TAP2 hsa:6891 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
TAP2 hsa:6891 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)
TAP2 hsa:6891 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
TAP2 hsa:6891 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
TAP2 hsa:6891 path:hsa05340 Primary immunodeficiency - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TAP2 TAP1 10973281 11717192 14508489 16181333 17204652 22076556 22790179 26192618 interaction type N/A ACSN
IRF1 TAP2 18694960 23180781 physical association anti tag coimmunoprecipitation InnateDB
RELA TAP2 18694960 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR TAP2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TAP2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 TAP2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TAP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
IRF1 TAP2 18694960 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 TAP2 18694960 trascriptional regulation,stimulation inferred by curator TFlink
RELA TAP2 18694960 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
TAP2 TAP1 11133832 11381133 12213826 14525934 16828748 17055437 18802093 19201886 19297616 24234451 25348397 26789246 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cross-linking study,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
TAP2 TAPBP 12213826 14525934 16828748 19201886 24234451 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
TAP2 PSMB5 14525934 15488952 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
TAP2 PSMB8 14525934 15488952 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TAP2 HLA-G 14525934 25348397 9103419 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TAP2 HLA-C 14525934 25348397 27898060 9551969 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
TAP2 APP 25348397 N/A physical interaction ComPPI
TAP2 B2M 25348397 N/A physical interaction ComPPI
TAP2 HLA-A 25348397 N/A physical interaction ComPPI
TAP2 HLA-E 25348397 N/A coimmunoprecipitation,physical interaction ComPPI
TAP2 FMNL1 25348397 N/A physical interaction ComPPI
TAP2 PSMG3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TAP2 RBM18 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TAP2 TCTN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TAP2 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TAP2 FGD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAP2 CKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAP2 ZNF281 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAP2 ATL3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAP2 MASTL 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAP2 TMCO3 25348397 N/A physical interaction ComPPI
TAP2 SLC17A2 25348397 N/A physical interaction ComPPI
TAP2 SCNN1D 25348397 N/A physical interaction ComPPI
TAP2 HTR3A 25348397 N/A physical interaction ComPPI
TAP2 CFTR 25348397 N/A physical interaction ComPPI
TAP2 PSMB9 15488952 24234451 25348397 physical association two hybrid ComPPI,IntAct
TAP2 TAP2 19297616 24234451 N/A cross-linking study IntAct
CALR TAP2 10618487 27898060 N/A N/A OmniPath
TAP2 CALR 10618487 27898060 N/A N/A OmniPath
TAP1 TAP2 10508608 10618487 11133832 11381133 12047747 12213826 125051506 12730134 16828748 17055437 19297616 19661920 24628792 27898060 N/A N/A OmniPath
TAP2 TAP1 10508608 10618487 11133832 11381133 12047747 12213826 125051506 12730134 16828748 17055437 19297616 19661920 24628792 27898060 N/A N/A OmniPath
TAP2 PDIA3 10618487 27898060 N/A N/A OmniPath
B2M TAP2 10618487 27898060 N/A N/A OmniPath
PDIA5 TAP2 10618487 27898060 N/A N/A OmniPath
TAPBP TAP2 10618487 12213826 16828748 27898060 N/A N/A OmniPath
TAP2 TAPBP 10618487 12213826 16828748 27898060 N/A N/A OmniPath

Visualization