GENE：ARX
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ARX |
| FullNmae | aristaless related homeobox |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:18060 |
| EnsembleID | ENSG00000004848 |
| Uniprot | Q96QS3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ARX | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ARX | GO:0000122,GO:0000785,GO:0000977,GO:0000978,GO:0000981,GO:0000981,GO:0000981,GO:0001227,GO:0001228,GO:0003682,GO:0005515,GO:0005634,GO:0006357,GO:0007411,GO:0010628,GO:0021759,GO:0021800,GO:0021831,GO:0021846,GO:0021853,GO:0035265,GO:0044241,GO:0045944,GO:0045944,GO:0046622,GO:0050678,GO:0072148,GO:1990837 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| YBX1 | ARX | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ARX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ARX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ARX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ARX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ARX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | ARX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | ARX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | ARX | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TACC3 | ARX | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RBM4 | ARX | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CLTC | ARX | 25348397 | N/A | physical interaction | ComPPI |
| AP2A1 | ARX | 25348397 | N/A | anti tag coimmunoprecipitation,physical interaction | ComPPI |
| CYFIP1 | ARX | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| STK39 | ARX | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CLINT1 | ARX | 25348397 | N/A | physical interaction | ComPPI |
| CLTB | ARX | 25348397 | N/A | physical interaction | ComPPI |
| KLC2 | ARX | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CLTA | ARX | 25348397 | N/A | physical interaction | ComPPI |
| SEC16A | ARX | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PIK3C2A | ARX | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| APOB | ARX | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GTSE1 | ARX | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MRRF | ARX | 25348397 | N/A | physical interaction | ComPPI |
| MIGA1 | ARX | 25348397 | N/A | physical interaction | ComPPI |
| CD99L2 | ARX | 25348397 | N/A | physical interaction | ComPPI |