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GENE：HSD17B3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HSD17B3
FullNmae hydroxysteroid 17-beta dehydrogenase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5212
EnsembleID ENSG00000130948
Uniprot P37058

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HSD17B3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HSD17B3 GO:0004303,GO:0005783,GO:0005783,GO:0005789,GO:0006694,GO:0006702,GO:0030283,GO:0030539,GO:0043231,GO:0047045,GO:0047045,GO:0061370,GO:0072582

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HSD17B3 hsa:3293 path:hsa00140 Steroid hormone biosynthesis - Homo sapiens (human)
HSD17B3 hsa:3293 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR HSD17B3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
TP73 HSD17B3 21245298 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 HSD17B3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 HSD17B3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HSD17B3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 HSD17B3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HSD17B3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HSD17B3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HSD17B3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HSD17B3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 HSD17B3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR HSD17B3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 HSD17B3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 HSD17B3 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
PPP1CC HSD17B3 25348397 N/A physical interaction ComPPI
ACTB HSD17B3 25348397 N/A physical interaction ComPPI
ERBB2 HSD17B3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
SMAD2 HSD17B3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
CDH1 HSD17B3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
BUB1 HSD17B3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
AHNAK HSD17B3 25348397 N/A physical interaction ComPPI
TAX1BP1 HSD17B3 25348397 N/A physical interaction ComPPI
CTNNA1 HSD17B3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PYGB HSD17B3 25348397 N/A physical interaction ComPPI
AMFR HSD17B3 25348397 N/A physical interaction ComPPI
BRAF HSD17B3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
MLH1 HSD17B3 20706999 24234451 25348397 physical association two hybrid ComPPI,IntAct
MCC HSD17B3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
HERC3 HSD17B3 25348397 N/A physical interaction ComPPI
DLC1 HSD17B3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PCP2 HSD17B3 25348397 N/A physical interaction ComPPI

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