GENE:SYNE2
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | SYNE2 |
FullNmae | spectrin repeat containing nuclear envelope protein 2 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:17084 |
EnsembleID | ENSG00000054654 |
Uniprot | Q8WXH0 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
SYNE2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
SYNE2 | GO:0003779,GO:0005515,GO:0005634,GO:0005635,GO:0005640,GO:0005654,GO:0005737,GO:0005739,GO:0005925,GO:0007097,GO:0016529,GO:0021817,GO:0030018,GO:0030335,GO:0031022,GO:0031258,GO:0031527,GO:0031965,GO:0031981,GO:0033017,GO:0034993,GO:0045111,GO:0051642,GO:0070062,GO:0140444,GO:1902017 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | SYNE2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
YBX1 | SYNE2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXP3 | SYNE2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | SYNE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | SYNE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | SYNE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | SYNE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | SYNE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | SYNE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | SYNE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | SYNE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | SYNE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TAL1 | SYNE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | SYNE2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000338542 | SYNE2 | N/A | rna interference,inhibition | experimental interaction detection | miRSponge |
URS0000338542 | SYNE2 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection,experimental interaction detection,experimental interaction detection | TarBase |
URS00000AA464 | SYNE2 | 20304954 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS0000521626 | SYNE2 | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000EED18 | SYNE2 | 21566225 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
URS000003ABC4 | SYNE2 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS000009262D | SYNE2 | 18591254 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00005651EE | SYNE2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000324096 | SYNE2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000019F055 | SYNE2 | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000006372A | SYNE2 | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
NDUFB9 | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
S100A4 | SYNE2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CALM1 | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
KEAP1 | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
APPL1 | SYNE2 | 23414517 24234451 25348397 | physical association | two hybrid fragment pooling approach,proximity ligation assay | ComPPI,IntAct |
MAPK1 | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
MAPK3 | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
JUN | SYNE2 | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
VAPA | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
UBC | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
FHOD1 | SYNE2 | 24234451 24880667 25348397 | physical association | anti bait coimmunoprecipitation,two hybrid,pull down,physical interaction | ComPPI,IntAct |
HEY1 | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
MAPK8IP2 | SYNE2 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
ARRB2 | SYNE2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
ABI1 | SYNE2 | 23414517 24234451 25348397 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
BIN1 | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
VAPB | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
HIF1AN | SYNE2 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
CUL7 | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
SUPT5H | SYNE2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CDC37 | SYNE2 | 24234451 25036637 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TRIM25 | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
PRPF4 | SYNE2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
TERF1 | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
PML | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
TERF2 | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
SOD1 | SYNE2 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SIRT7 | SYNE2 | 25348397 | N/A | physical interaction | ComPPI |
MTNR1B | SYNE2 | 24234451 25348397 26514267 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
SYNE2 | SUN2 | 22555292 22632968 24234451 25348397 | colocalization,association,physical association | pull down,x-ray crystallography,physical interaction,confocal microscopy | ComPPI,IntAct |
SYNE2 | SDHA | 25348397 | N/A | physical interaction | ComPPI |
SYNE2 | BRAP | 24234451 25348397 25820252 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
SYNE2 | OBSL1 | 25348397 | N/A | physical interaction | ComPPI |
SYNE2 | RNASEH2B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SYNE2 | GAN | 25348397 | N/A | physical interaction | ComPPI |
SYNE2 | CTDNEP1 | 25348397 | N/A | physical interaction | ComPPI |
SYNE2 | BCAR1 | 24234451 25348397 28007913 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
HSPA5 | SYNE2 | 24234451 30021884 | physical association | cross-linking study | IntAct |
MESD | SYNE2 | 24234451 30021884 | physical association | cross-linking study | IntAct |
SYNE2 | COL23A1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
SYNE2 | STXBP3 | 24234451 30021884 | physical association | cross-linking study | IntAct |
PRKDC | SYNE2 | 24234451 30021884 | physical association | cross-linking study | IntAct |
RPL7A | SYNE2 | 24234451 30021884 | physical association | cross-linking study | IntAct |
NPM1 | SYNE2 | 24234451 30021884 | physical association | cross-linking study | IntAct |