Gene Information gene info

GENE:SYNE2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SYNE2
FullNmae spectrin repeat containing nuclear envelope protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17084
EnsembleID ENSG00000054654
Uniprot Q8WXH0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SYNE2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SYNE2 GO:0003779,GO:0005515,GO:0005634,GO:0005635,GO:0005640,GO:0005654,GO:0005737,GO:0005739,GO:0005925,GO:0007097,GO:0016529,GO:0021817,GO:0030018,GO:0030335,GO:0031022,GO:0031258,GO:0031527,GO:0031965,GO:0031981,GO:0033017,GO:0034993,GO:0045111,GO:0051642,GO:0070062,GO:0140444,GO:1902017

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SYNE2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 SYNE2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 SYNE2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 SYNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SYNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SYNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SYNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SYNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SYNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SYNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SYNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SYNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SYNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SYNE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 SYNE2 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 SYNE2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS00000AA464 SYNE2 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS0000521626 SYNE2 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 SYNE2 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003ABC4 SYNE2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D SYNE2 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00005651EE SYNE2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 SYNE2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000019F055 SYNE2 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A SYNE2 24374217 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NDUFB9 SYNE2 25348397 N/A physical interaction ComPPI
S100A4 SYNE2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CALM1 SYNE2 25348397 N/A physical interaction ComPPI
KEAP1 SYNE2 25348397 N/A physical interaction ComPPI
APPL1 SYNE2 23414517 24234451 25348397 physical association two hybrid fragment pooling approach,proximity ligation assay ComPPI,IntAct
MAPK1 SYNE2 25348397 N/A physical interaction ComPPI
MAPK3 SYNE2 25348397 N/A physical interaction ComPPI
JUN SYNE2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
VAPA SYNE2 25348397 N/A physical interaction ComPPI
UBC SYNE2 25348397 N/A physical interaction ComPPI
FHOD1 SYNE2 24234451 24880667 25348397 physical association anti bait coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
HEY1 SYNE2 25348397 N/A physical interaction ComPPI
MAPK8IP2 SYNE2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ARRB2 SYNE2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ABI1 SYNE2 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
BIN1 SYNE2 25348397 N/A physical interaction ComPPI
VAPB SYNE2 25348397 N/A physical interaction ComPPI
HIF1AN SYNE2 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
CUL7 SYNE2 25348397 N/A physical interaction ComPPI
SUPT5H SYNE2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC37 SYNE2 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM25 SYNE2 25348397 N/A physical interaction ComPPI
PRPF4 SYNE2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TERF1 SYNE2 25348397 N/A physical interaction ComPPI
PML SYNE2 25348397 N/A physical interaction ComPPI
TERF2 SYNE2 25348397 N/A physical interaction ComPPI
SOD1 SYNE2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SIRT7 SYNE2 25348397 N/A physical interaction ComPPI
MTNR1B SYNE2 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
SYNE2 SUN2 22555292 22632968 24234451 25348397 colocalization,association,physical association pull down,x-ray crystallography,physical interaction,confocal microscopy ComPPI,IntAct
SYNE2 SDHA 25348397 N/A physical interaction ComPPI
SYNE2 BRAP 24234451 25348397 25820252 physical association two hybrid,physical interaction ComPPI,IntAct
SYNE2 OBSL1 25348397 N/A physical interaction ComPPI
SYNE2 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SYNE2 GAN 25348397 N/A physical interaction ComPPI
SYNE2 CTDNEP1 25348397 N/A physical interaction ComPPI
SYNE2 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
HSPA5 SYNE2 24234451 30021884 physical association cross-linking study IntAct
MESD SYNE2 24234451 30021884 physical association cross-linking study IntAct
SYNE2 COL23A1 24234451 30021884 physical association cross-linking study IntAct
SYNE2 STXBP3 24234451 30021884 physical association cross-linking study IntAct
PRKDC SYNE2 24234451 30021884 physical association cross-linking study IntAct
RPL7A SYNE2 24234451 30021884 physical association cross-linking study IntAct
NPM1 SYNE2 24234451 30021884 physical association cross-linking study IntAct

Visualization