GENE:MLLT10
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MLLT10 |
| FullNmae | MLLT10 histone lysine methyltransferase DOT1L cofactor |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16063 |
| EnsembleID | ENSG00000078403 |
| Uniprot | P55197 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MLLT10 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MLLT10 | GO:0003677,GO:0003682,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0006357,GO:0031491,GO:0031491,GO:0032991,GO:0042393,GO:0042393,GO:0045944,GO:0046872 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | MLLT10 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | MLLT10 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | MLLT10 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| HIF1A | MLLT10 | 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| FOXP3 | MLLT10 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | MLLT10 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | MLLT10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | MLLT10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | MLLT10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | MLLT10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | MLLT10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | MLLT10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | MLLT10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | MLLT10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | MLLT10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | MLLT10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | MLLT10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | MLLT10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000028BB8 | MLLT10 | 17612493 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00001F0C23 | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000393C7 | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EBD4B | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CBE63 | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000039E1E1 | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000039A25B | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A281 | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003D8730 | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000080D0A | MLLT10 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000058276F | MLLT10 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000122ED0 | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000029979D | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000032EF64 | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000000B1C9 | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A07C1 | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237CBD | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000031E12 | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000324096 | MLLT10 | 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AA845 | MLLT10 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000045E0EC | MLLT10 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B59A2 | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003CCBB9 | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000055BBE5 | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171525 | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012A1DD | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000572E11 | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000028D811 | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005A8ED | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | MLLT10 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000535FDD | MLLT10 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SKP1 | MLLT10 | 20203130 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| AFF1 | MLLT10 | 25348397 | N/A | physical interaction | ComPPI |
| TMPO | MLLT10 | 25348397 | N/A | physical interaction | ComPPI |
| SMARCB1 | MLLT10 | 25348397 | N/A | physical interaction | ComPPI |
| CTNNB1 | MLLT10 | 20203130 21103407 24234451 25348397 27898060 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct,OmniPath |
| CENPJ | MLLT10 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| SS18 | MLLT10 | 11423977 25348397 27898060 | N/A | two hybrid,physical interaction,in vivo | ComPPI,OmniPath |
| MLLT10 | YEATS4 | 11756182 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| MLLT10 | RGPD5 | 11774384 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD |
| MLLT10 | DOT1L | 14525934 15851025 20203130 20431927 21103407 24234451 25348397 26496610 27898060 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD,IntAct,OmniPath |
| MLLT10 | MLLT1 | 14525934 15856011 20203130 24234451 25348397 | association | anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| MLLT10 | MLLT3 | 20203130 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MLLT10 | DISC1 | 25348397 | N/A | physical interaction | ComPPI |
| MLLT10 | NDEL1 | 17043677 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| MLLT10 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| MLLT10 | TMPO | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MLLT10 | ZNF526 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MLLT10 | MLLT6 | 20203130 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MLLT10 | TCP10L | 25348397 | N/A | physical interaction | ComPPI |
| MLLT10 | KIF6 | 25348397 | N/A | physical interaction | ComPPI |
| MLLT10 | PMF1 | 25348397 | N/A | physical interaction | ComPPI |
| MLLT10 | TCF4 | 21103407 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MLLT10 | MLLT10 | 10860745 14525934 | N/A | experimental interaction detection | HPRD |
| H1-5 | MLLT10 | 24234451 30021884 | physical association | cross-linking study | IntAct |
