Gene Information gene info

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GENE：PNKD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PNKD
FullNmae PNKD metallo-beta-lactamase domain containing
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9153
EnsembleID ENSG00000127838
Uniprot Q8N490

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PNKD immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PNKD GO:0004416,GO:0005515,GO:0005634,GO:0005739,GO:0005739,GO:0016020,GO:0019243,GO:0032225,GO:0042053,GO:0046872,GO:0046929,GO:0050884,GO:0099523

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP PNKD 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PNKD 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PNKD 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PNKD 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PNKD 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001B341F PNKD 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 PNKD 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000F31F4 PNKD 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000B59A2 PNKD 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002CAE0C PNKD 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001123BD PNKD 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 PNKD 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000FFC8B PNKD 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002D0FC3 PNKD 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000321A1A PNKD 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDA4 PNKD 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 PNKD 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 PNKD 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 PNKD 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EXOC5 PNKD 25348397 N/A physical interaction ComPPI
MAD2L2 PNKD 24234451 25348397 29656893 association anti tag coimmunoprecipitation ComPPI,IntAct
GMNN PNKD 25348397 N/A physical interaction ComPPI
KCTD9 PNKD 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TAF12 PNKD 25348397 N/A physical interaction ComPPI
EIF2B2 PNKD 25348397 N/A physical interaction ComPPI
MAPK3 PNKD 24234451 25066297 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct,OmniPath
NUP85 PNKD 25348397 N/A physical interaction ComPPI
PEX19 PNKD 25348397 N/A physical interaction ComPPI
ILK PNKD 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TARBP2 PNKD 25348397 N/A physical interaction ComPPI
PPFIBP1 PNKD 25348397 N/A physical interaction ComPPI
STAG1 PNKD 25348397 N/A physical interaction ComPPI
TSC2 PNKD 25348397 N/A physical interaction ComPPI
NUP98 PNKD 25348397 N/A physical interaction ComPPI
DIAPH3 PNKD 25348397 N/A physical interaction ComPPI
IPO11 PNKD 25348397 N/A physical interaction ComPPI
GEMIN2 PNKD 25348397 N/A physical interaction ComPPI
IPO7 PNKD 25348397 N/A physical interaction ComPPI
IPO8 PNKD 25348397 N/A physical interaction ComPPI
AP1B1 PNKD 25348397 N/A physical interaction ComPPI
SCARB2 PNKD 25348397 N/A physical interaction ComPPI
NCSTN PNKD 25348397 N/A physical interaction ComPPI
PPARGC1B PNKD 25348397 N/A physical interaction ComPPI
PJA1 PNKD 25348397 N/A physical interaction ComPPI
CAMK1 PNKD 25348397 N/A physical interaction ComPPI
BTAF1 PNKD 25348397 N/A physical interaction ComPPI
TFIP11 PNKD 25348397 N/A physical interaction ComPPI
XPO4 PNKD 25348397 N/A physical interaction ComPPI
EIF2B5 PNKD 25348397 N/A physical interaction ComPPI
EIF3J PNKD 25348397 N/A physical interaction ComPPI
MLXIP PNKD 25348397 N/A physical interaction ComPPI
EIF4G3 PNKD 25348397 N/A physical interaction ComPPI
TNPO2 PNKD 25348397 N/A physical interaction ComPPI
GBF1 PNKD 25348397 N/A physical interaction ComPPI
NUP107 PNKD 25348397 N/A physical interaction ComPPI
EIF2B4 PNKD 25348397 N/A physical interaction ComPPI
STAG2 PNKD 25348397 N/A physical interaction ComPPI
ARL2BP PNKD 25348397 N/A physical interaction ComPPI
DICER1 PNKD 25348397 N/A physical interaction ComPPI
NCAPD2 PNKD 25348397 N/A physical interaction ComPPI
EYA2 PNKD 25348397 N/A physical interaction ComPPI
MYL12B PNKD 14525934 15188056 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
HAUS7 PNKD 25348397 N/A physical interaction ComPPI
NUP37 PNKD 25348397 N/A physical interaction ComPPI
IPO9 PNKD 25348397 N/A physical interaction ComPPI
FBXO30 PNKD 25348397 N/A physical interaction ComPPI
NUP160 PNKD 25348397 N/A physical interaction ComPPI
STOM PNKD 25348397 N/A physical interaction ComPPI
MAGEA11 PNKD 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PPP6R2 PNKD 25348397 N/A physical interaction ComPPI
KIFBP PNKD 25348397 N/A physical interaction ComPPI
RADIL PNKD 25348397 N/A physical interaction ComPPI
PNKD ENO3 25348397 N/A two hybrid,in vitro ComPPI
PNKD APP 25348397 N/A physical interaction ComPPI
PNKD RTF2 25348397 N/A physical interaction ComPPI
PNKD SETX 25348397 N/A physical interaction ComPPI
PNKD TBC1D15 25348397 N/A physical interaction ComPPI
PNKD HEATR3 25348397 N/A physical interaction ComPPI
PNKD RANBP6 25348397 N/A physical interaction ComPPI
PNKD FDFT1 25348397 N/A physical interaction ComPPI
PNKD SAAL1 25348397 N/A physical interaction ComPPI
PNKD CIP2A 25348397 N/A physical interaction ComPPI
PNKD NCAPD3 25348397 N/A physical interaction ComPPI
PNKD GOLPH3L 25348397 N/A physical interaction ComPPI
PNKD EXOC7 25348397 N/A physical interaction ComPPI
PNKD INIP 25348397 N/A physical interaction ComPPI
PNKD PRMT9 25348397 N/A physical interaction ComPPI
PNKD PBXIP1 25348397 N/A physical interaction ComPPI
PNKD RRP1 25348397 N/A physical interaction ComPPI
PNKD HOOK2 25348397 N/A physical interaction ComPPI
PNKD ECD 25348397 N/A physical interaction ComPPI
PNKD PPP6R1 25348397 N/A physical interaction ComPPI
PNKD KIF14 25348397 N/A physical interaction ComPPI
PNKD ASAH1 25348397 N/A physical interaction ComPPI
PNKD NCAPH2 25348397 N/A physical interaction ComPPI
PNKD INTS3 25348397 N/A physical interaction ComPPI
PNKD MIGA1 25348397 N/A physical interaction ComPPI
PNKD EIF2B3 25348397 N/A physical interaction ComPPI
PNKD VPS8 25348397 N/A physical interaction ComPPI
PNKD ARMCX3 25348397 N/A physical interaction ComPPI
PNKD DCAF11 25348397 N/A physical interaction ComPPI
PNKD LSS 25348397 N/A physical interaction ComPPI
PNKD ARFGEF3 25348397 N/A physical interaction ComPPI
PNKD PPP4R3B 25348397 N/A physical interaction ComPPI
PNKD DYM 25348397 N/A physical interaction ComPPI
PNKD ATRIP 25348397 N/A physical interaction ComPPI
PNKD GON4L 25348397 N/A physical interaction ComPPI
PNKD ARMC6 25348397 N/A physical interaction ComPPI
PNKD OTUB1 25348397 N/A physical interaction ComPPI
PNKD FHIP2A 25348397 N/A physical interaction ComPPI
PNKD COA3 23260140 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PNKD SLC25A13 23260140 24234451 25348397 association blue native page ComPPI,IntAct
CETN3 PNKD 25348397 N/A physical interaction ComPPI
GOLPH3 PNKD 25348397 N/A physical interaction ComPPI
DCUN1D5 PNKD 25348397 N/A physical interaction ComPPI
ARL14EP PNKD 25348397 N/A physical interaction ComPPI
PNKD ACADM 24234451 30021884 physical association cross-linking study IntAct

Visualization










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