Gene Information gene info

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GENE：UNC5C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UNC5C
FullNmae unc-5 netrin receptor C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12569
EnsembleID ENSG00000182168
Uniprot O95185

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UNC5C immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UNC5C GO:0005042,GO:0005043,GO:0005515,GO:0005886,GO:0006915,GO:0007411,GO:0007420,GO:0009986,GO:0015631,GO:0019901,GO:0030027,GO:0030175,GO:0030425,GO:0030426,GO:0033564,GO:0035234,GO:0038007,GO:0043025,GO:0043065,GO:0045202,GO:0051094,GO:0061643,GO:1990791,GO:2000243,GO:2001222

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UNC5C hsa:8633 path:hsa04360 Axon guidance - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR UNC5C 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 UNC5C 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 UNC5C 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 UNC5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UNC5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UNC5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UNC5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UNC5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UNC5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 UNC5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 UNC5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 UNC5C 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000075BEA7 UNC5C 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 UNC5C 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000018E72A UNC5C 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 UNC5C 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 UNC5C 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 UNC5C 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 UNC5C 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 UNC5C 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00002F0130 UNC5C 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000F7766 UNC5C 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000029EBD UNC5C 22291592 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NTN1 UNC5C 25361965 interaction type N/A PTMCode2
UNC5C NTN1 25361965 interaction type N/A PTMCode2
DAPK1 UNC5C 25361965 interaction type N/A PTMCode2
UNC5C DAPK1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NPM1 UNC5C 25348397 N/A physical interaction ComPPI
NTRK1 UNC5C 25348397 N/A physical interaction ComPPI
NTN1 UNC5C 18719102 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction,in vitro ComPPI,IntAct
UNC5C DAPK1 25348397 N/A physical interaction ComPPI
UNC5C TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NTN1 UNC5C 10399920 12810718 27898060 stimulant N/A OmniPath

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