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GENE：LRRC4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LRRC4
FullNmae leucine rich repeat containing 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15586
EnsembleID ENSG00000128594
Uniprot Q9HBW1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LRRC4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LRRC4 GO:0005515,GO:0005886,GO:0043197,GO:0050804,GO:0060076,GO:0097119,GO:0098685,GO:0098839,GO:0098978,GO:0099560,GO:1904861

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LRRC4 hsa:64101 path:hsa04360 Axon guidance - Homo sapiens (human)
LRRC4 hsa:64101 path:hsa04514 Cell adhesion molecules - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR LRRC4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 LRRC4 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LRRC4 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 LRRC4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
EGR1 LRRC4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A LRRC4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 LRRC4 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00001CC379 LRRC4 24404152 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000005A8ED LRRC4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 LRRC4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 LRRC4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 LRRC4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 LRRC4 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ITGB5 LRRC4 25348397 N/A physical interaction ComPPI
SPP1 LRRC4 25348397 N/A physical interaction ComPPI
TBCD LRRC4 25348397 N/A physical interaction ComPPI
MID1 LRRC4 25348397 N/A physical interaction ComPPI
XPO4 LRRC4 25348397 N/A physical interaction ComPPI
TNPO2 LRRC4 25348397 N/A physical interaction ComPPI
AGO2 LRRC4 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct

Visualization










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