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GENE：ALDOB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ALDOB
FullNmae aldolase, fructose-bisphosphate B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:417
EnsembleID ENSG00000136872
Uniprot P05062

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ALDOB immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ALDOB GO:0004332,GO:0004332,GO:0005515,GO:0005815,GO:0005829,GO:0005829,GO:0005829,GO:0006000,GO:0006094,GO:0006096,GO:0006096,GO:0006096,GO:0006116,GO:0008092,GO:0030388,GO:0030388,GO:0032781,GO:0034451,GO:0042802,GO:0051117,GO:0060090,GO:0061609,GO:0061609,GO:0061624,GO:0070061,GO:0070062,GO:0070072,GO:1905856

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ALDOB hsa:229 path:hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human)
ALDOB hsa:229 path:hsa00030 Pentose phosphate pathway - Homo sapiens (human)
ALDOB hsa:229 path:hsa00051 Fructose and mannose metabolism - Homo sapiens (human)
ALDOB hsa:229 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ALDOB hsa:229 path:hsa01200 Carbon metabolism - Homo sapiens (human)
ALDOB hsa:229 path:hsa01230 Biosynthesis of amino acids - Homo sapiens (human)
ALDOB hsa:229 path:hsa04066 HIF-1 signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP ALDOB 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
HNF1A ALDOB 15933209 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ALDOB 15933209 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 ALDOB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ALDOB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ALDOB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
DBP ALDOB 8383844 trascriptional regulation,stimulation inferred by curator TFlink
PPARGC1A ALDOB 16891307 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000451A1 ALDOB 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
BBS4 ALDOB 25361965 interaction type N/A PTMCode2
ALDOB BBS4 25361965 interaction type N/A PTMCode2
BBS7 ALDOB 25361965 interaction type N/A PTMCode2
ALDOB BBS7 25361965 interaction type N/A PTMCode2
BBS2 ALDOB 25361965 interaction type N/A PTMCode2
ALDOB BBS2 25361965 interaction type N/A PTMCode2
ALDOB ALDOB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TXN2 ALDOB 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HSPA8 ALDOB 11241348 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
SMAD4 ALDOB 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
BBS2 ALDOB 18000879 24234451 25348397 colocalization,physical association two hybrid,coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
SRC ALDOB 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
BUB1 ALDOB 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
MAP2K4 ALDOB 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
HUS1 ALDOB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RPE ALDOB 25348397 N/A physical interaction ComPPI
SUMO3 ALDOB 25348397 N/A physical interaction ComPPI
STK11 ALDOB 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
CTNNA1 ALDOB 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
ALDOB ATP6V1E1 11399750 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ALDOB APP 25348397 N/A physical interaction ComPPI
ALDOB BBS1 18000879 24234451 25348397 colocalization,physical association two hybrid,coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
ALDOB BBS4 18000879 24234451 25348397 colocalization,physical association two hybrid,coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
ALDOB BBS7 18000879 24234451 25348397 colocalization,physical association two hybrid,coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
ALDOB MUC20 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ALDOB HIVEP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ALDOB ALDOA 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ALDOB AGXT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ALDOB BMPR1A 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
ALDOB CDKN2A 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
ALDOB DCC 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
ALDOB FLCN 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
ALDOB MCC 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
ALDOB MLH1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
ALDOB MLH3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
ALDOB NRAS 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
ALDOB ALDOB 11679716 14525934 N/A experimental interaction detection HPRD

Visualization










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