GENE：DPF3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | DPF3 |
| FullNmae | double PHD fingers 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17427 |
| EnsembleID | ENSG00000205683 |
| Uniprot | Q92784 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| DPF3 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| DPF3 | GO:0000785,GO:0005654,GO:0006338,GO:0006357,GO:0007399,GO:0007517,GO:0008150,GO:0008270,GO:0016514,GO:0030071,GO:0035060,GO:0045597,GO:0045663,GO:0070316,GO:0071565,GO:0071565,GO:2000045,GO:2000781,GO:2000819 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| DPF3 | hsa:8110 | path:hsa03082 | ATP-dependent chromatin remodeling - Homo sapiens (human) |
| DPF3 | hsa:8110 | path:hsa04714 | Thermogenesis - Homo sapiens (human) |
| DPF3 | hsa:8110 | path:hsa05225 | Hepatocellular carcinoma - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | DPF3 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | DPF3 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | DPF3 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | DPF3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | DPF3 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| NR1I2 | DPF3 | 19129222 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | DPF3 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | DPF3 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | DPF3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000003ABC4 | DPF3 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000011166D | DPF3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | DPF3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | DPF3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000EF0B | DPF3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E226A | DPF3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000044FD7 | DPF3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029D9F1 | DPF3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005194EC | DPF3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F0130 | DPF3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000020CEC2 | DPF3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076995 | DPF3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SMARCE1 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| SMARCC1 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| TUBA3E | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| SMARCD1 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| SMARCA4 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| HEY1 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| CSNK2A1 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| UBR5 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1B | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| RELA | DPF3 | 22334708 24234451 25348397 | association | physical interaction,chromatin immunoprecipitation assay | ComPPI,IntAct |
| SMARCB1 | DPF3 | 24234451 25348397 30108113 | association | pull down,physical interaction | ComPPI,IntAct |
| CSNK2A2 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| TUBA8 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| ACTL6A | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| DCX | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| H3C1 | DPF3 | 24234451 25348397 27402533 | N/A | x-ray crystallography | ComPPI,IntAct |
| SS18 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| ACTL6B | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| NFKB1 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| BRD7 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| NEUROD1 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| SNRNP200 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| SMARCD3 | DPF3 | 18765789 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| SMARCC2 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| SMARCD2 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| ARID1A | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| PBRM1 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| ARID2 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| CSNK2B | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| TIMM50 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| EEF1A2 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| AIFM1 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| BCL7A | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| AHSA1 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| UBR4 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| SMARCA2 | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| HSPA1L | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| BCL7C | DPF3 | 25348397 | N/A | physical interaction | ComPPI |
| DPF3 | TECR | 25348397 | N/A | physical interaction | ComPPI |
| IL6 | DPF3 | 22334708 24234451 | association | chromatin immunoprecipitation assay | IntAct |