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GENE：MAGI1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MAGI1
FullNmae membrane associated guanylate kinase, WW and PDZ domain containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:946
EnsembleID ENSG00000151276
Uniprot Q96QZ7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MAGI1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MAGI1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MAGI1 GO:0005515,GO:0005524,GO:0005654,GO:0005730,GO:0005737,GO:0005737,GO:0005886,GO:0005911,GO:0005911,GO:0005912,GO:0005923,GO:0007155,GO:0007165,GO:0007166,GO:0022409,GO:0030054,GO:0042995,GO:0051393,GO:0065003,GO:0071944

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MAGI1 hsa:9223 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
MAGI1 hsa:9223 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
MAGI1 hsa:9223 path:hsa04530 Tight junction - Homo sapiens (human)
MAGI1 hsa:9223 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MAGI1 ADRB1 20005715 interaction type N/A PSP
MAGI1 RPS6KA3 20005715 interaction type N/A PSP
MAGI1 RPS6KA2 20005715 interaction type N/A PSP
MAGI1 RPS6KA1 20005715 interaction type N/A PSP
MAGI1 RPS6KA1 16217014 18988627 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR MAGI1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 MAGI1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MAGI1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C MAGI1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 MAGI1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MAGI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MAGI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MAGI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MAGI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MAGI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MAGI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MAGI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MAGI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MAGI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MAGI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MAGI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 MAGI1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 MAGI1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000005481D MAGI1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
MAGI1 FCHSD2 25361965 interaction type N/A PTMCode2
FCHSD2 MAGI1 25361965 interaction type N/A PTMCode2
DLL1 MAGI1 25361965 interaction type N/A PTMCode2
MAGI1 DLL1 25361965 interaction type N/A PTMCode2
CDH1 MAGI1 25361965 interaction type N/A PTMCode2
MAGI1 CDH1 25361965 interaction type N/A PTMCode2
SYNPO MAGI1 25361965 interaction type N/A PTMCode2
MAGI1 SYNPO 25361965 interaction type N/A PTMCode2
LRP2 MAGI1 25361965 interaction type N/A PTMCode2
MAGI1 LRP2 25361965 interaction type N/A PTMCode2
CTNNB1 MAGI1 25361965 interaction type N/A PTMCode2
MAGI1 CTNNB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FAM110A MAGI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EDC3 MAGI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
AMOT MAGI1 14525934 16043488 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
WBP2 MAGI1 25348397 N/A physical interaction ComPPI
FAM53C MAGI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TP53BP2 MAGI1 14525934 25348397 9169421 N/A experimental interaction detection,in vitro ComPPI,HPRD
RAC1 MAGI1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
LARP1 MAGI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CBY1 MAGI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TIAM1 MAGI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GAB2 MAGI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HDAC4 MAGI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RTKN MAGI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF1 MAGI1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ACTN4 MAGI1 12042308 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CDH1 MAGI1 25348397 N/A physical interaction ComPPI
TFAP2A MAGI1 14525934 25348397 9169421 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAGI1 RPS6KA3 14525934 16217014 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
MAGI1 RPS6KA2 25348397 N/A two hybrid ComPPI
MAGI1 RPS6KA1 14525934 16217014 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
MAGI1 CLCN5 14525934 25348397 9169421 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAGI1 ADGRB1 14525934 23782696 25348397 27898060 9647739 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
MAGI1 NET1 11350080 19586902 24234451 25348397 27898060 30126976 N/A two hybrid,physical interaction,in vitro,in vivo,p8 filamentous phage display ComPPI,IntAct,OmniPath
MAGI1 SYNPO 12042308 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MAGI1 CTNNB1 10772923 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
MAGI1 GBP2 14525934 16169070 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
MAGI1 IGSF5 12773569 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
MAGI1 DAG1 25348397 N/A in vitro ComPPI
MAGI1 RASA1 14525934 25348397 9169421 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAGI1 IL6R 14525934 25348397 9169421 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAGI1 LRP2 11274227 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
MAGI1 BZW1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MAGI1 SFN 15778465 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
MAGI1 FCHSD2 14627983 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
MAGI1 WBP1 25348397 N/A physical interaction ComPPI
MAGI1 ATN1 14525934 25348397 9647693 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
MAGI1 DDN 25348397 N/A physical interaction ComPPI
MAGI1 SSTR3 25348397 N/A physical interaction ComPPI
MAGI1 LATS1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MAGI1 LATS2 25348397 N/A physical interaction ComPPI
MAGI1 RAPGEF2 11168587 24234451 25348397 27898060 physical association coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
MAGI1 MOV10 25348397 N/A physical interaction ComPPI
MAGI1 NXF1 25348397 N/A physical interaction ComPPI
MAGI1 CYYR1 25348397 N/A physical interaction ComPPI
MAGI1 LDLRAD4 25348397 N/A physical interaction ComPPI
MAGI1 PTPN14 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 KCTD3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 KIF13B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 ZBTB21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 KSR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 LRFN1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 DENND1A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 SH3PXD2A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 SRGAP2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 EIF4E2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 SIPA1L1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 LIMA1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 TESK2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 DCLK1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 ZNF638 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 MAST3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 SRSF12 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 PPM1H 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 SYDE1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 DENND4C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 AGAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 CDC25B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 CDK16 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 FAM110B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 USP21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 MAPKAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 ANKRD34A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 CGN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 NF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 TBC1D25 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 NADK 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 PHLDB2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 MAP3K21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 RASAL2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 CAMSAP2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 LPIN3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 CDC25C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 MELK 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 PLEKHA7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 KIF1C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 DEPDC1B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 NAV1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 DENND4A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 AFDN 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 STARD13 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 RPTOR 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 SH3RF3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 PLEKHA5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 SH3BP4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 HDAC7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 RAB3IP 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 INPP5E 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAGI1 HNRNPL 25348397 N/A physical interaction ComPPI
MAGI1 ADRB1 16316992 24234451 25348397 N/A peptide array ComPPI,IntAct
MAGI1 MYC 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
IQGAP1 MAGI1 22662192 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,confocal microscopy,proximity ligation assay ComPPI,IntAct
KCNJ10 MAGI1 24234451 24561201 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
KIF1B MAGI1 25348397 N/A two hybrid ComPPI
ASIC3 MAGI1 14525934 15317815 N/A experimental interaction detection,two hybrid HPRD
MAGI1 CDK9 23746844 24234451 association chromatin immunoprecipitation assay IntAct
MAGI1 CDK8 23746844 24234451 association chromatin immunoprecipitation assay IntAct
MAGI1 POLR2A 23746844 24234451 association chromatin immunoprecipitation assay IntAct
CYSLTR2 MAGI1 24234451 30126976 N/A p8 filamentous phage display IntAct
PTEN MAGI1 15629897 15951562 27898060 N/A N/A OmniPath
MAGI1 CDH23 18971469 27898060 N/A N/A OmniPath

Visualization










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