GENE：LRRFIP1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | LRRFIP1 |
| FullNmae | LRR binding FLII interacting protein 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:6702 |
| EnsembleID | ENSG00000124831 |
| Uniprot | Q32MZ4 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| LRRFIP1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| LRRFIP1 | GO:0000122,GO:0000978,GO:0000978,GO:0000981,GO:0001227,GO:0003677,GO:0003725,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0005829,GO:0005856,GO:0005886,GO:0006357,GO:0042803,GO:0045296 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LRRFIP1 | TNF | 16199883 23180781 24567534 | physical association | anti tag coimmunoprecipitation | InnateDB |
| EZH2 | LRRFIP1 | 23180781 24567534 | physical association | anti tag coimmunoprecipitation | InnateDB |
| SUZ12 | LRRFIP1 | 23180781 24567534 | physical association | anti tag coimmunoprecipitation | InnateDB |
| LRRFIP1 | EZH2 | 23180781 24567534 | physical association | anti tag coimmunoprecipitation | InnateDB |
| LRRFIP1 | LRRFIP1 | 23180781 24567534 | physical association | anti tag coimmunoprecipitation | InnateDB |
| LRRFIP1 | UBB | 23180781 24816145 | ubiquitination reaction | ubiquitinase assay | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | LRRFIP1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | LRRFIP1 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | LRRFIP1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | LRRFIP1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | LRRFIP1 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | LRRFIP1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | LRRFIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | LRRFIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | LRRFIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | LRRFIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | LRRFIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | LRRFIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | LRRFIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | LRRFIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | LRRFIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | LRRFIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | LRRFIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | LRRFIP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000009262D | LRRFIP1 | 19559015 \N | rna interference,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
| URS000009262D | LRRFIP1 | 18927107 19559015 24690174 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | miR2Disease,TarBase |
| URS0000065D58 | LRRFIP1 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection,experimental interaction detection,experimental interaction detection | TarBase |
| URS00000F31F4 | LRRFIP1 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000EED18 | LRRFIP1 | 21566225 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS00000B59A2 | LRRFIP1 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000070B1D | LRRFIP1 | 23622248 23824327 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS000021D7C8 | LRRFIP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001C770D | LRRFIP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000166778 | LRRFIP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018CD09 | LRRFIP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C0FCB | LRRFIP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075E2C3 | LRRFIP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005FDCD1 | LRRFIP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| FLII | LRRFIP1 | 25361965 | interaction type | N/A | PTMCode2 |
| LRRFIP1 | FLII | 25361965 | interaction type | N/A | PTMCode2 |
| LRRFIP1 | GRIP1 | 25361965 | interaction type | N/A | PTMCode2 |
| GRIP1 | LRRFIP1 | 25361965 | interaction type | N/A | PTMCode2 |
| LRRFIP1 | LRRFIP1 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| DPY30 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| PRKDC | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| DHX9 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| U2AF2 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| RFC2 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| IQGAP1 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| EPRS1 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| RPLP0 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| FKBP3 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| RNF2 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| TFR2 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| CCNB1 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| MYD88 | LRRFIP1 | 15952741 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| DYNC1H1 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| FLII | LRRFIP1 | 10366446 14525934 24234451 25348397 9671805 | physical association | two hybrid,experimental interaction detection,pull down,physical interaction,in vitro | ComPPI,HPRD,IntAct |
| LRRFIP1 | RTCB | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | DDX1 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | RPLP0P6 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | MRE11 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | LGR4 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | MED4 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | CEP44 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | TMOD1 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | IFI16 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | SH2D2A | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | DBN1 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | TMOD3 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | TMOD4 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | IFT74 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | TCEAL2 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | GAS2L1 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | MCTS1 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | BRCA1 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | SERPINB5 | 25348397 | N/A | physical interaction | ComPPI |
| LRRFIP1 | ESR1 | 24234451 25348397 25604459 | association | tandem affinity purification | ComPPI,IntAct |
| RTRAF | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| STK38L | LRRFIP1 | 24234451 30108113 | association | proximity-dependent biotin identification | IntAct |
| NUMA1 | LRRFIP1 | 24234451 30021884 | physical association | cross-linking study | IntAct |