GENE：MBNL2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MBNL2 |
| FullNmae | muscleblind like splicing regulator 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16746 |
| EnsembleID | ENSG00000139793 |
| Uniprot | Q5VZF2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MBNL2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| MBNL2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MBNL2 | GO:0003723,GO:0003723,GO:0005634,GO:0005654,GO:0005737,GO:0006397,GO:0008380,GO:0043484,GO:0043484,GO:0046872,GO:1990837 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | MBNL2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | MBNL2 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | MBNL2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | MBNL2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | MBNL2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | MBNL2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | MBNL2 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | MBNL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | MBNL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | MBNL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | MBNL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | MBNL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | MBNL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | MBNL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | MBNL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | MBNL2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000041E949 | MBNL2 | 19229866 \N | rna interference,inhibition | array technology,miRNA interference luciferase reporter assay | miRSponge |
| URS000041E949 | MBNL2 | 18927107 19229866 25416803 | mrna cleavage,inhibition | array technology,miRNA interference luciferase reporter assay | miR2Disease,TarBase |
| URS0000237AF9 | MBNL2 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000122ED0 | MBNL2 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000006FDD4 | MBNL2 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002A71AD | MBNL2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065D58 | MBNL2 | 25416803 26840300 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS00002152A8 | MBNL2 | 25416803 26840300 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS00001DE669 | MBNL2 | 25416803 26840300 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS00004719AB | MBNL2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B7E30 | MBNL2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000028DE3F | MBNL2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002233F4 | MBNL2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000285DCB | MBNL2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EFEC1 | MBNL2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AC389 | MBNL2 | 25416803 26881967 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BMI1 | MBNL2 | 25348397 | N/A | physical interaction | ComPPI |
| ENO1 | MBNL2 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | MBNL2 | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | MBNL2 | 25348397 | N/A | physical interaction | ComPPI |
| NXF1 | MBNL2 | 25348397 | N/A | physical interaction | ComPPI |
| MBNL1 | MBNL2 | 25348397 | N/A | physical interaction | ComPPI |
| MBNL2 | HSD17B2 | 25348397 | N/A | physical interaction | ComPPI |
| NAB2 | MBNL2 | 12531921 15692572 18190927 18682389 19840948 27898060 | N/A | N/A | OmniPath |