Gene Information gene info

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GENE：PDZK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PDZK1
FullNmae PDZ domain containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8821
EnsembleID ENSG00000174827
Uniprot Q5T2W1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PDZK1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PDZK1 GO:0005102,GO:0005124,GO:0005515,GO:0005886,GO:0005886,GO:0005903,GO:0015879,GO:0016324,GO:0030165,GO:0031526,GO:0031528,GO:0032414,GO:0043495,GO:0044070,GO:0044877,GO:0070062,GO:0072659,GO:0090314,GO:1904064,GO:1905477,GO:1990961

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SSTR5 PDZK1 16012170 23180781 physical association two hybrid,pull down InnateDB

Source Target Pmid Interactiontype Methods Database
AR PDZK1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 PDZK1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 PDZK1 18414489 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation array,chromatin immunoprecipitation assay TFlink
GATA2 PDZK1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 PDZK1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 PDZK1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PDZK1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PDZK1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PDZK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PDZK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PDZK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PDZK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000521626 PDZK1 17612493 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
CFTR PDZK1 25361965 interaction type N/A PTMCode2
PDZK1 CFTR 25361965 interaction type N/A PTMCode2
SSTR5 PDZK1 25361965 interaction type N/A PTMCode2
PDZK1 SSTR5 25361965 interaction type N/A PTMCode2
PDZK1 ABCC2 25361965 interaction type N/A PTMCode2
ABCC2 PDZK1 25361965 interaction type N/A PTMCode2
PDZK1 SLC22A12 25361965 interaction type N/A PTMCode2
SLC22A12 PDZK1 25361965 interaction type N/A PTMCode2
PDZK1 SLC15A2 25361965 interaction type N/A PTMCode2
SLC15A2 PDZK1 25361965 interaction type N/A PTMCode2
SLC22A4 PDZK1 25361965 interaction type N/A PTMCode2
PDZK1 SLC22A4 25361965 interaction type N/A PTMCode2
SLC22A11 PDZK1 25361965 interaction type N/A PTMCode2
PDZK1 SLC22A11 25361965 interaction type N/A PTMCode2
SCARB1 PDZK1 25361965 interaction type N/A PTMCode2
PDZK1 SCARB1 25361965 interaction type N/A PTMCode2
PDZK1IP1 PDZK1 25361965 interaction type N/A PTMCode2
PDZK1 PDZK1IP1 25361965 interaction type N/A PTMCode2
GUCY2C PDZK1 25361965 interaction type N/A PTMCode2
PDZK1 GUCY2C 25361965 interaction type N/A PTMCode2
SLC17A1 PDZK1 25361965 interaction type N/A PTMCode2
PDZK1 SLC17A1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I PDZK1 25348397 N/A physical interaction ComPPI
ZBED1 PDZK1 25348397 N/A physical interaction ComPPI
ZBTB5 PDZK1 25348397 N/A physical interaction ComPPI
SLC9A3R1 PDZK1 25348397 N/A physical interaction ComPPI
SLC9A3R2 PDZK1 25348397 N/A physical interaction ComPPI
SCARB1 PDZK1 10829064 12119305 14525934 14551195 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
AKAP10 PDZK1 14525934 14531806 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
CFTR PDZK1 11051556 12471024 12615054 14525934 15553237 18045536 24234451 25348397 27898060 acetylation reaction,colocalization,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
PTGIR PDZK1 21653824 23457445 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ABCC2 PDZK1 10496535 12615054 14525934 25348397 27898060 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
CSNK2A2 PDZK1 25348397 N/A physical interaction ComPPI
SLC9A3 PDZK1 14525934 14531806 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PDZK1 CLCN3 12471024 14525934 24234451 25348397 physical association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PDZK1 SLC22A12 14525934 14531806 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PDZK1 PDZK1IP1 12754212 12837682 14525934 14531806 25348397 27898060 9461128 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PDZK1 SSTR5 14525934 16012170 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PDZK1 SLC22A5 14525934 15523054 15553237 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
PDZK1 GFAP 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PDZK1 SLC22A11 14525934 15553237 16236806 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PDZK1 SLC15A2 14525934 15553237 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PDZK1 SLCO1A2 14525934 15553237 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
PDZK1 ABCA1 14525934 16192282 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
PDZK1 PEX5 14525934 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PDZK1 FARP2 25348397 N/A physical interaction ComPPI
PDZK1 SLK 25348397 N/A physical interaction ComPPI
PDZK1 APP 25348397 N/A physical interaction ComPPI
PDZK1 ABCC4 25348397 N/A physical interaction ComPPI
PDZK1 CDC37 25348397 N/A physical interaction ComPPI
PDZK1 AKT1 25348397 N/A physical interaction ComPPI
PDZK1 SLC34A1 25348397 N/A physical interaction ComPPI
PDZK1 ASNSD1 25348397 N/A physical interaction ComPPI
PDZK1 BCR 15494376 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PDZK1 FRYL 25348397 N/A physical interaction ComPPI
PDZK1 SHKBP1 25348397 N/A physical interaction ComPPI
PDZK1 KCTD3 25348397 N/A physical interaction ComPPI
PDZK1 SH2D5 25348397 N/A physical interaction ComPPI
PDZK1 KCTD17 25348397 N/A physical interaction ComPPI
PDZK1 SLC6A6 25348397 N/A physical interaction ComPPI
PDZK1 KCTD2 25348397 N/A physical interaction ComPPI
PDZK1 COLEC12 25348397 N/A physical interaction ComPPI
PDZK1 SLC4A7 25348397 N/A physical interaction ComPPI
PDZK1 KCTD5 25348397 N/A physical interaction ComPPI
PDZK1 KLHL17 25348397 N/A physical interaction ComPPI
PDZK1 SLC5A6 25348397 N/A physical interaction ComPPI
PDZK1 SLC19A3 25348397 N/A physical interaction ComPPI
PDZK1 USP3 25348397 N/A physical interaction ComPPI
PDZK1 DECR2 25348397 N/A physical interaction ComPPI
PDZK1 KLHL24 25348397 N/A physical interaction ComPPI
PDZK1 ECI2 25348397 N/A physical interaction ComPPI
PDZK1 CDK5RAP1 25348397 N/A physical interaction ComPPI
PDZK1 SLC1A3 25348397 N/A physical interaction ComPPI
PDZK1 GUCY2C 11950846 24234451 25348397 N/A pull down ComPPI,IntAct
ARHGAP17 PDZK1 25348397 N/A physical interaction ComPPI
OTULIN PDZK1 25348397 N/A physical interaction ComPPI
PDZK1 SLC17A1 14525934 14531806 N/A experimental interaction detection,two hybrid HPRD
SLC22A4 PDZK1 14525934 14531806 15553237 N/A experimental interaction detection,two hybrid HPRD
PDZK1 SLC26A6 14525934 14531806 24234451 30126976 N/A experimental interaction detection,p8 filamentous phage display,two hybrid HPRD,IntAct
CYSLTR2 PDZK1 24234451 30126976 N/A p8 filamentous phage display IntAct
SDK2 PDZK1 24234451 30126976 N/A p8 filamentous phage display IntAct
SLC15A5 PDZK1 24234451 30126976 N/A p8 filamentous phage display IntAct
PUS3 PDZK1 24234451 30126976 N/A p8 filamentous phage display IntAct
GPR17 PDZK1 24234451 30126976 N/A p8 filamentous phage display IntAct
PIGL PDZK1 24234451 30126976 N/A p8 filamentous phage display IntAct
PDZK1 CLCN3 12471024 27898060 N/A N/A OmniPath

Visualization










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