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GENE：RNASEH2A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RNASEH2A
FullNmae ribonuclease H2 subunit A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18518
EnsembleID ENSG00000104889
Uniprot O75792

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RNASEH2A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RNASEH2A GO:0003723,GO:0004523,GO:0004523,GO:0004540,GO:0005654,GO:0005829,GO:0006260,GO:0006298,GO:0006298,GO:0006298,GO:0006401,GO:0032299,GO:0032299,GO:0032299,GO:0043137,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RNASEH2A hsa:10535 path:hsa03030 DNA replication - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 RNASEH2A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC RNASEH2A 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 RNASEH2A 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F1 RNASEH2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RNASEH2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RNASEH2A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000C85B2 RNASEH2A 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
EDF1 RNASEH2A 25348397 N/A physical interaction ComPPI
H2BC4 RNASEH2A 25348397 N/A physical interaction ComPPI
TTF1 RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AP1M1 RNASEH2A 25348397 N/A physical interaction ComPPI
RAD51 RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IPO7 RNASEH2A 25348397 N/A physical interaction ComPPI
ITSN1 RNASEH2A 25348397 N/A physical interaction ComPPI
OSBP2 RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H3C1 RNASEH2A 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ICAM5 RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LAMA5 RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM25 RNASEH2A 25348397 N/A physical interaction ComPPI
PATJ RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDOR1 RNASEH2A 25348397 N/A physical interaction ComPPI
FBXW11 RNASEH2A 25348397 N/A physical interaction ComPPI
SHMT2 RNASEH2A 25348397 N/A physical interaction ComPPI
POLDIP3 RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FYTTD1 RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX39B RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRDX2 RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UGDH RNASEH2A 25348397 N/A physical interaction ComPPI
KPTN RNASEH2A 25348397 N/A physical interaction ComPPI
ITLN1 RNASEH2A 25348397 N/A physical interaction ComPPI
H2BC11 RNASEH2A 25348397 N/A physical interaction ComPPI
CDK10 RNASEH2A 25348397 N/A physical interaction ComPPI
MOV10 RNASEH2A 25348397 N/A physical interaction ComPPI
LGMN RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHF20L1 RNASEH2A 25348397 N/A physical interaction ComPPI
DOCK6 RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSRC1 RNASEH2A 25348397 N/A physical interaction ComPPI
SETD3 RNASEH2A 25348397 N/A physical interaction ComPPI
IARS2 RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KLHL36 RNASEH2A 25348397 N/A physical interaction ComPPI
RNASEH2A RNASEH2C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNASEH2A RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

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