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GENE：SRXN1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SRXN1
FullNmae sulfiredoxin 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16132
EnsembleID ENSG00000271303
Uniprot Q9BYN0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SRXN1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SRXN1 GO:0005515,GO:0005524,GO:0005737,GO:0005789,GO:0005829,GO:0006979,GO:0016667,GO:0032542,GO:0032542,GO:0034599,GO:0098869

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NFKB1 SRXN1 18761713 19027064 19747488 21725609 23178297 23572150 26192618 interaction type N/A ACSN
NFE2L2 SRXN1 10441483 10821856 10874044 11279008 11909699 12356737 12511571 15521073 16219762 17512463 18761713 19027064 19747488 23850759 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
ETS1 SRXN1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SRXN1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F1 SRXN1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000016FF9C SRXN1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000016FD1A SRXN1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A SRXN1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000012A1DD SRXN1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000008DA94 SRXN1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075AAA0 SRXN1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 SRXN1 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ZNRD2 SRXN1 25348397 N/A physical interaction ComPPI
CFL1 SRXN1 25348397 N/A physical interaction ComPPI
PSMD7 SRXN1 25348397 N/A physical interaction ComPPI
TACC3 SRXN1 25348397 N/A physical interaction ComPPI
TLE3 SRXN1 25348397 N/A physical interaction ComPPI
TPM2 SRXN1 25348397 N/A physical interaction ComPPI
PIR SRXN1 25348397 N/A physical interaction ComPPI
PRDX1 SRXN1 18172504 24234451 25348397 N/A classical fluorescence spectroscopy,x-ray crystallography,physical interaction,enzymatic study ComPPI,IntAct
PSMA5 SRXN1 25348397 N/A physical interaction ComPPI
TRIP6 SRXN1 25348397 N/A physical interaction ComPPI
UBE2B SRXN1 25348397 N/A physical interaction ComPPI
TOM1L2 SRXN1 25348397 N/A physical interaction ComPPI
UBA2 SRXN1 25348397 N/A physical interaction ComPPI
ZRANB2 SRXN1 25348397 N/A physical interaction ComPPI
STAT6 SRXN1 25348397 N/A physical interaction ComPPI
TTC1 SRXN1 25348397 N/A physical interaction ComPPI
PSMD2 SRXN1 25348397 N/A physical interaction ComPPI
IGBP1 SRXN1 25348397 N/A physical interaction ComPPI
SRPK2 SRXN1 25348397 N/A physical interaction ComPPI
STUB1 SRXN1 25348397 N/A physical interaction ComPPI
TPM4 SRXN1 25348397 N/A physical interaction ComPPI
RCN1 SRXN1 25348397 N/A physical interaction ComPPI
UCHL5 SRXN1 25348397 N/A physical interaction ComPPI
ZPR1 SRXN1 25348397 N/A physical interaction ComPPI
GOT1 SRXN1 25348397 N/A physical interaction ComPPI
AHCYL1 SRXN1 25348397 N/A physical interaction ComPPI
TPM1 SRXN1 25348397 N/A physical interaction ComPPI
USP9X SRXN1 25348397 N/A physical interaction ComPPI
ATP6V1F SRXN1 25348397 N/A physical interaction ComPPI
PPM1G SRXN1 25348397 N/A physical interaction ComPPI
USP34 SRXN1 25348397 N/A physical interaction ComPPI
TTLL12 SRXN1 25348397 N/A physical interaction ComPPI
SRXN1 THADA 25348397 N/A physical interaction ComPPI
SRXN1 TTC9C 25348397 N/A physical interaction ComPPI
SRXN1 SULT1A1 25348397 N/A physical interaction ComPPI
SRXN1 UBXN7 25348397 N/A physical interaction ComPPI
SRXN1 TUBB6 25348397 N/A physical interaction ComPPI
SRXN1 UNK 25348397 N/A physical interaction ComPPI
ATP6V1B2 SRXN1 25348397 N/A physical interaction ComPPI

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