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GENE：ATG16L2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATG16L2
FullNmae autophagy related 16 like 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25464
EnsembleID ENSG00000168010
Uniprot Q8NAA4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATG16L2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ATG16L2 GO:0000045,GO:0000045,GO:0000421,GO:0005654,GO:0005829,GO:0015031,GO:0016236,GO:0034045,GO:0034274,GO:0039689

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATG16L2 hsa:89849 path:hsa04140 Autophagy - animal - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ATG16L2 ATG5 21575909 23180781 physical association two hybrid,pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ATG16L2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ATG16L2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ATG16L2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ATG16L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATG16L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATG16L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ATG16L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ATG16L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATG16L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATG16L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR ATG16L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ATG16L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ATG16L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 ATG16L2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 ATG16L2 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
TK1 ATG16L2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAP1LC3B ATG16L2 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
FBXW7 ATG16L2 25348397 N/A physical interaction ComPPI
XPO1 ATG16L2 25348397 N/A physical interaction ComPPI
GABARAP ATG16L2 20562859 24234451 25348397 N/A pull down ComPPI,IntAct
CHUK ATG16L2 25348397 N/A physical interaction ComPPI
ATG5 ATG16L2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
IKBIP ATG16L2 24234451 30021884 physical association cross-linking study IntAct
ATG12 ATG16L2 10406794 11897782 17986448 27898060 N/A N/A OmniPath
ATG5 ATG16L2 10406794 17012802 17192262 17986448 19889643 21575909 23064152 27898060 N/A N/A OmniPath

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