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GENE：CREB3L4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CREB3L4
FullNmae cAMP responsive element binding protein 3 like 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18854
EnsembleID ENSG00000143578
Uniprot Q8TEY5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CREB3L4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CREB3L4 GO:0000139,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0005515,GO:0005634,GO:0005654,GO:0005739,GO:0005783,GO:0005789,GO:0005794,GO:0006357,GO:0006986,GO:0007283,GO:0031965,GO:0045944,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CREB3L4 hsa:148327 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04152 AMPK signaling pathway - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04211 Longevity regulating pathway - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04714 Thermogenesis - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04725 Cholinergic synapse - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04728 Dopaminergic synapse - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04911 Insulin secretion - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04915 Estrogen signaling pathway - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04916 Melanogenesis - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04918 Thyroid hormone synthesis - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04922 Glucagon signaling pathway - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04926 Relaxin signaling pathway - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04927 Cortisol synthesis and secretion - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04931 Insulin resistance - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04934 Cushing syndrome - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04935 Growth hormone synthesis, secretion and action - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa04962 Vasopressin-regulated water reabsorption - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa05016 Huntington disease - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa05020 Prion disease - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa05030 Cocaine addiction - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa05031 Amphetamine addiction - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa05034 Alcoholism - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa05161 Hepatitis B - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
CREB3L4 hsa:148327 path:hsa05215 Prostate cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 CREB3L4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CREB3L4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CREB3L4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CREB3L4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CREB3L4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CREB3L4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
GET3 CREB3L4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SOX9 CREB3L4 25348397 N/A physical interaction ComPPI
CREB3 CREB3L4 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
GANAB CREB3L4 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CREM CREB3L4 25348397 N/A physical interaction ComPPI
NXF1 CREB3L4 25348397 N/A physical interaction ComPPI
MOV10 CREB3L4 25348397 N/A physical interaction ComPPI

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