Gene Information gene info

GENE:CERS4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CERS4
FullNmae ceramide synthase 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23747
EnsembleID ENSG00000090661
Uniprot Q9HA82

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CERS4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CERS4 GO:0003677,GO:0005515,GO:0005789,GO:0030148,GO:0046513,GO:0046513,GO:0050291,GO:0050291,GO:0050291

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CERS4 hsa:79603 path:hsa00600 Sphingolipid metabolism - Homo sapiens (human)
CERS4 hsa:79603 path:hsa01100 Metabolic pathways - Homo sapiens (human)
CERS4 hsa:79603 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 CERS4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CERS4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CERS4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CERS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CERS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CERS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CERS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CERS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CERS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CERS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CERS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CERS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 CERS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 CERS4 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS0000544FF1 CERS4 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 CERS4 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 CERS4 19536157 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 CERS4 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 CERS4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB CERS4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 CERS4 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000008A99 CERS4 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00004CCA62 CERS4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A92 CERS4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 CERS4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF CERS4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 CERS4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075A513 CERS4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000010F787 CERS4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000009A9A2 CERS4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA CERS4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00002152A8 CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000AB32B CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000027352D CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003D4175 CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075A760 CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001481F9 CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001496AE CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075BDAA CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075B538 CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000259AE4 CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000EC1BE CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000512C88 CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000041FA2C CERS4 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 CERS4 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
UPK1B CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
JAGN1 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SERP2 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LHFPL5 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FATE1 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLC7A1 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN9 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX8 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NEU1 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX7 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLP2 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MS4A1 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ITGAM CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SCD CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CYB5R3 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NAT8 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SCAMP5 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FXYD6 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLC35F6 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LPAR1 CERS4 25348397 N/A physical interaction ComPPI
GPR151 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IER3IP1 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMIM11A CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IPPK CERS4 25348397 N/A physical interaction ComPPI
TMEM176A CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCL4L1 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CLEC1A CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLC35A1 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TOMM6 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CERS4 SLC13A4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CERS4 TMEM254 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CERS4 TMEM72 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

Visualization