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GENE：SPNS1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPNS1
FullNmae SPNS lysolipid transporter 1, lysophospholipid
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30621
EnsembleID ENSG00000169682
Uniprot Q9H2V7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPNS1 lysosomal_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SPNS1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SPNS1 GO:0005215,GO:0005515,GO:0005743,GO:0005765,GO:0016020,GO:0022857,GO:0033700,GO:0035751,GO:0051977,GO:0055085

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NLRX1 SPNS1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
UNC93B1 SPNS1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 SPNS1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SPNS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SPNS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SPNS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SPNS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SPNS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00006DE17B SPNS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000F6E49 SPNS1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000272039 SPNS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC SPNS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000023F008 SPNS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A SPNS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000585553 SPNS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BE495 SPNS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D SPNS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 SPNS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 SPNS1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B SPNS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A SPNS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 SPNS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 SPNS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 SPNS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED SPNS1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BCL2L1 SPNS1 25361965 interaction type N/A PTMCode2
SPNS1 BCL2L1 25361965 interaction type N/A PTMCode2
CYCS SPNS1 25361965 interaction type N/A PTMCode2
SPNS1 CYCS 25361965 interaction type N/A PTMCode2
SPNS1 BCL2 25361965 interaction type N/A PTMCode2
BCL2 SPNS1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CYCS SPNS1 12815463 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
BCL2L1 SPNS1 12815463 14525934 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,confocal microscopy ComPPI,HPRD,IntAct
BCL2 SPNS1 12815463 14525934 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,confocal microscopy ComPPI,HPRD,IntAct
SPNS1 NLRX1 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPNS1 UNC93B1 25348397 N/A physical interaction ComPPI
SPNS1 CLN5 25348397 N/A physical interaction ComPPI
SPNS1 TES 25348397 N/A physical interaction ComPPI
SPNS1 SDHB 12815463 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
SPNS1 USP19 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
HSCB SPNS1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
SPNS1 HTR2C 24234451 28298427 physical association ubiquitin reconstruction IntAct
SPNS1 ADORA2A 24234451 28298427 physical association ubiquitin reconstruction IntAct
SPNS1 BDKRB2 24234451 28298427 physical association ubiquitin reconstruction IntAct
SPNS1 CCR8 24234451 28298427 physical association ubiquitin reconstruction IntAct
SPNS1 CCR9 24234451 28298427 physical association ubiquitin reconstruction IntAct
SPNS1 CHRM5 24234451 28298427 physical association ubiquitin reconstruction IntAct
SPNS1 BCL2L1 12815463 27898060 inhibition N/A OmniPath
SPNS1 BCL2 12815463 27898060 inhibition N/A OmniPath
NLRX1 SPNS1 21903422 27898060 N/A N/A OmniPath

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