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GENE：ALDH1B1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ALDH1B1
FullNmae aldehyde dehydrogenase 1 family member B1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:407
EnsembleID ENSG00000137124
Uniprot P30837

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ALDH1B1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ALDH1B1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ALDH1B1 GO:0004029,GO:0005654,GO:0005739,GO:0005759,GO:0005829,GO:0005975,GO:0006068,GO:0043878,GO:0051287

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ALDH1B1 hsa:219 path:hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa00053 Ascorbate and aldarate metabolism - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa00071 Fatty acid degradation - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa00310 Lysine degradation - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa00330 Arginine and proline metabolism - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa00340 Histidine metabolism - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa00380 Tryptophan metabolism - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa00410 beta-Alanine metabolism - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa00561 Glycerolipid metabolism - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa00620 Pyruvate metabolism - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa00770 Pantothenate and CoA biosynthesis - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)
ALDH1B1 hsa:219 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ADRB2 ALDH1B1 23180781 23798571 physical association affinity chromatography technology InnateDB

Source Target Pmid Interactiontype Methods Database
AR ALDH1B1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 ALDH1B1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ALDH1B1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ALDH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ALDH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ALDH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ALDH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ALDH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ALDH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ALDH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ALDH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ALDH1B1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002971AB ALDH1B1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002C0FCB ALDH1B1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 ALDH1B1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005FDE70 ALDH1B1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C308D ALDH1B1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 ALDH1B1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000237E04 ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F ALDH1B1 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FABP2 ALDH1B1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LDHB ALDH1B1 25348397 N/A physical interaction ComPPI
LDHA ALDH1B1 25348397 N/A physical interaction ComPPI
KEAP1 ALDH1B1 25348397 N/A physical interaction ComPPI
MAP1LC3B ALDH1B1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PDCD10 ALDH1B1 25348397 N/A physical interaction ComPPI
JUN ALDH1B1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
SUFU ALDH1B1 25348397 N/A physical interaction ComPPI
CUL3 ALDH1B1 25348397 N/A physical interaction ComPPI
UBC ALDH1B1 25348397 N/A physical interaction ComPPI
PGM1 ALDH1B1 25348397 N/A physical interaction ComPPI
NTRK1 ALDH1B1 25348397 N/A physical interaction ComPPI
STIP1 ALDH1B1 25348397 N/A physical interaction ComPPI
XRN2 ALDH1B1 25348397 N/A physical interaction ComPPI
MYC ALDH1B1 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CFTR ALDH1B1 25348397 N/A physical interaction ComPPI
ECT2 ALDH1B1 25348397 N/A physical interaction ComPPI
EXOSC10 ALDH1B1 25348397 N/A physical interaction ComPPI
MAP1LC3A ALDH1B1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UQCRC2 ALDH1B1 25348397 N/A physical interaction ComPPI
PDK1 ALDH1B1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PDCD6IP ALDH1B1 25348397 N/A physical interaction ComPPI
RPL6 ALDH1B1 25348397 N/A physical interaction ComPPI
FEM1B ALDH1B1 25348397 N/A physical interaction ComPPI
OAT ALDH1B1 25348397 N/A physical interaction ComPPI
FAF2 ALDH1B1 25348397 N/A physical interaction ComPPI
HSPD1 ALDH1B1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
UQCRB ALDH1B1 25348397 N/A physical interaction ComPPI
LLGL1 ALDH1B1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UQCRFS1 ALDH1B1 25348397 N/A physical interaction ComPPI
SOD2 ALDH1B1 25348397 N/A physical interaction ComPPI
MGST3 ALDH1B1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
OFD1 ALDH1B1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
XPNPEP1 ALDH1B1 25348397 N/A physical interaction ComPPI
UQCRQ ALDH1B1 25348397 N/A physical interaction ComPPI
KSR1 ALDH1B1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
FBXO6 ALDH1B1 25348397 N/A physical interaction ComPPI
ETFA ALDH1B1 25348397 N/A physical interaction ComPPI
FH ALDH1B1 25348397 N/A physical interaction ComPPI
ALDH5A1 ALDH1B1 25348397 N/A physical interaction ComPPI
HEXB ALDH1B1 25348397 N/A physical interaction ComPPI
FN1 ALDH1B1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
HDAC1 ALDH1B1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SGO1 ALDH1B1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIBADH ALDH1B1 25348397 N/A physical interaction ComPPI
SRP68 ALDH1B1 25348397 N/A physical interaction ComPPI
ESD ALDH1B1 25348397 N/A physical interaction ComPPI
ZNF746 ALDH1B1 25348397 N/A physical interaction ComPPI
ALDH1B1 OGFOD1 25348397 N/A physical interaction ComPPI
ALDH1B1 TATDN1 25348397 N/A physical interaction ComPPI
ALDH1B1 DHRS4 25348397 N/A physical interaction ComPPI
ALDH1B1 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ALDH1B1 ATL3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ALDH1B1 MRPL58 20186120 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UBR7 ALDH1B1 25348397 N/A physical interaction ComPPI
ALDH1B1 ZNF341 24234451 30021884 physical association cross-linking study IntAct
ALDH1B1 PITPNM3 24234451 30021884 physical association cross-linking study IntAct
ALDH1B1 COL6A6 24234451 30021884 physical association cross-linking study IntAct
ALDH1B1 C7ORF50 24234451 30021884 physical association cross-linking study IntAct
ALDH1B1 TOP1 24234451 30021884 physical association cross-linking study IntAct

Visualization










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