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GENE：ALOXE3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ALOXE3
FullNmae arachidonate lipoxygenase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13743
EnsembleID ENSG00000179148
Uniprot Q9BYJ1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ALOXE3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ALOXE3 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ALOXE3 GO:0005506,GO:0005515,GO:0005829,GO:0006665,GO:0016702,GO:0019233,GO:0019369,GO:0019369,GO:0019372,GO:0019372,GO:0019372,GO:0034440,GO:0035357,GO:0043651,GO:0043651,GO:0045444,GO:0046513,GO:0050486,GO:0051120,GO:0051120,GO:0051120,GO:0051122,GO:0051122,GO:0061436,GO:0106255,GO:0106256

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ALOXE3 hsa:59344 path:hsa00590 Arachidonic acid metabolism - Homo sapiens (human)
ALOXE3 hsa:59344 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ALOXE3 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 ALOXE3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF ALOXE3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ALOXE3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ALOXE3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ALOXE3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ALOXE3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 ALOXE3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ALOXE3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
HSPA8 ALOXE3 25348397 N/A physical interaction ComPPI
NECTIN2 ALOXE3 25348397 N/A physical interaction ComPPI
GLYR1 ALOXE3 25348397 N/A physical interaction ComPPI
SRC ALOXE3 25348397 N/A physical interaction ComPPI
VEGFB ALOXE3 25348397 N/A physical interaction ComPPI
TGM1 ALOXE3 22622417 24234451 25348397 physical association proximity ligation assay ComPPI,IntAct
HSPD1 ALOXE3 25348397 N/A physical interaction ComPPI

Visualization










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