GENE：APOA5
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | APOA5 |
| FullNmae | apolipoprotein A5 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17288 |
| EnsembleID | ENSG00000110243 |
| Uniprot | Q6Q788 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| APOA5 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| APOA5 | GO:0005515,GO:0005543,GO:0005576,GO:0005576,GO:0005615,GO:0005769,GO:0005770,GO:0005788,GO:0005794,GO:0006641,GO:0006641,GO:0006869,GO:0008047,GO:0008201,GO:0008289,GO:0010898,GO:0010898,GO:0010902,GO:0019433,GO:0019899,GO:0031210,GO:0031210,GO:0033344,GO:0033700,GO:0034361,GO:0034364,GO:0034364,GO:0034372,GO:0035473,GO:0042157,GO:0042246,GO:0042627,GO:0042627,GO:0042632,GO:0042632,GO:0045723,GO:0045723,GO:0048260,GO:0050750,GO:0050996,GO:0051006,GO:0051006,GO:0055090,GO:0055090,GO:0060228,GO:0060229,GO:0060230,GO:0070325,GO:0070328,GO:0070328,GO:0070328 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| APOA5 | hsa:116519 | path:hsa03320 | PPAR signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| YBX1 | APOA5 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| USF1 | APOA5 | 15684402 18572192 20054229 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | APOA5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | APOA5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | APOA5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | APOA5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | APOA5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | APOA5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PPARA | APOA5 | 16448983 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PPARGC1A | APOA5 | 16891307 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RORA | APOA5 | 16448983 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SREBF1 | APOA5 | 15317819 16448983 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| USF2 | APOA5 | 15684402 18572192 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000006372A | APOA5 | 24387992 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS00002CEB74 | APOA5 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CE046 | APOA5 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000157FBE | APOA5 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004818BD | APOA5 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SMARCD1 | APOA5 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| LPL | APOA5 | 15178420 24234451 25348397 | N/A | surface plasmon resonance,surface plasmon resonance array | ComPPI,IntAct |
| RAB5B | APOA5 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| SELENOS | APOA5 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| FAS | APOA5 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| TTPA | APOA5 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| APOA5 | MORN4 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| APOA5 | LPL | 15178420 21773006 27898060 | stimulant | N/A | OmniPath |