Gene Information gene info

GENE:CACNA2D2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CACNA2D2
FullNmae calcium voltage-gated channel auxiliary subunit alpha2delta 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1400
EnsembleID ENSG00000007402
Uniprot Q9NY47

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CACNA2D2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CACNA2D2 GO:0005245,GO:0005886,GO:0005891,GO:0034765,GO:0046872,GO:0070588

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CACNA2D2 hsa:9254 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
CACNA2D2 hsa:9254 path:hsa04260 Cardiac muscle contraction - Homo sapiens (human)
CACNA2D2 hsa:9254 path:hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)
CACNA2D2 hsa:9254 path:hsa04921 Oxytocin signaling pathway - Homo sapiens (human)
CACNA2D2 hsa:9254 path:hsa05410 Hypertrophic cardiomyopathy - Homo sapiens (human)
CACNA2D2 hsa:9254 path:hsa05412 Arrhythmogenic right ventricular cardiomyopathy - Homo sapiens (human)
CACNA2D2 hsa:9254 path:hsa05414 Dilated cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 CACNA2D2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C CACNA2D2 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 CACNA2D2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CACNA2D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CACNA2D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CACNA2D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CACNA2D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 CACNA2D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CACNA2D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CACNA2D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CACNA2D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005FDE70 CACNA2D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002004E0 CACNA2D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D15B CACNA2D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000192A75 CACNA2D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF CACNA2D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC0F4 CACNA2D2 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HNRNPL CACNA2D2 25348397 N/A physical interaction ComPPI
TAZ CACNA2D2 25348397 N/A physical interaction ComPPI
DEFA1 CACNA2D2 25348397 N/A physical interaction ComPPI
USP2 CACNA2D2 25348397 N/A physical interaction ComPPI
PON2 CACNA2D2 25348397 N/A physical interaction ComPPI
PTPRK CACNA2D2 25348397 N/A physical interaction ComPPI
PTCH1 CACNA2D2 25348397 N/A physical interaction ComPPI
CACNA2D2 IGHA1 15174051 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
TANK CACNA2D2 24234451 30561431 association virotrap IntAct
TNIP1 CACNA2D2 24234451 30561431 association virotrap IntAct

Visualization